ATE82588T1 - Zuchtverfahren fuer leukocyten. - Google Patents

Zuchtverfahren fuer leukocyten.

Info

Publication number
ATE82588T1
ATE82588T1 AT87903509T AT87903509T ATE82588T1 AT E82588 T1 ATE82588 T1 AT E82588T1 AT 87903509 T AT87903509 T AT 87903509T AT 87903509 T AT87903509 T AT 87903509T AT E82588 T1 ATE82588 T1 AT E82588T1
Authority
AT
Austria
Prior art keywords
leukocytes
culturing
cultivation procedure
cultivation
procedure
Prior art date
Application number
AT87903509T
Other languages
English (en)
Inventor
Georgiann B Melink
Raji A Shankar
Original Assignee
Endotronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endotronics Inc filed Critical Endotronics Inc
Application granted granted Critical
Publication of ATE82588T1 publication Critical patent/ATE82588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT87903509T 1986-04-28 1987-04-27 Zuchtverfahren fuer leukocyten. ATE82588T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85682786A 1986-04-28 1986-04-28
EP87903509A EP0302894B1 (de) 1986-04-28 1987-04-27 Zuchtverfahren für leukocyten
PCT/US1987/000924 WO1987006610A1 (en) 1986-04-28 1987-04-27 Method of culturing leukocytes

Publications (1)

Publication Number Publication Date
ATE82588T1 true ATE82588T1 (de) 1992-12-15

Family

ID=25324599

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87903509T ATE82588T1 (de) 1986-04-28 1987-04-27 Zuchtverfahren fuer leukocyten.

Country Status (6)

Country Link
US (2) US5541105A (de)
EP (1) EP0302894B1 (de)
JP (1) JP2529321B2 (de)
AT (1) ATE82588T1 (de)
DE (1) DE3782736T2 (de)
WO (1) WO1987006610A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263634B1 (de) * 1986-09-29 1993-08-11 Suzuki Shokan Co. Ltd. Verfahren für die Zuführung von Kulturmedium und Kultursystem
AU2925789A (en) * 1987-12-17 1989-07-19 Browning's Clinical Pathology Services Limited Lymphokine activation of cells for adoptive immunotherapy, e.g. of hiv infection
US4999298A (en) * 1988-04-27 1991-03-12 W. R. Grace & Co.-Conn. Hollow fiber bioreactor culture system and method
CA2015294A1 (en) * 1989-04-28 1990-10-28 John J. Rinehart Generation and expansion of lak cells
GR1001034B (el) * 1989-07-21 1993-03-31 Ortho Pharma Corp Μεθοδος διεγερσης του πολλαπλασιασμου λεμφοκυτταρων περιφερειακου αιματος.
JPH05502369A (ja) * 1989-09-14 1993-04-28 セルコ、インコーポレイテッド 養子免疫療法に用いられる生体外増殖リンパ性細胞の製造方法
AU7954191A (en) * 1990-05-30 1991-12-31 Cellco, Inc. Culturing bone marrow cells for adoptive immunotherapy
WO1993001277A1 (en) * 1991-07-04 1993-01-21 Japan Tobacco Inc. Process for culturing t precursor cell line
AP1261A (en) 1998-02-24 2004-03-19 Sisters Of Providence In Oregon Composition containing an OX-40 receptor binding agent or a nucleic acid encoding the same and methods for enhancing antigen-specific immune response.
DE19945162A1 (de) * 1999-09-21 2001-04-26 Herbert Maerkl Verfahren zur Kultivierung von Zellen, Membranmodul, Verwendung eines Membranmoduls und Reaktionssystem zur Kultivierung von Zellen
EP2029722B1 (de) 2006-05-22 2019-10-16 Biovest International, Inc. Verfahren und system zur zellproduktion
JP2010519937A (ja) 2007-03-05 2010-06-10 カリディアンビーシーティー、インコーポレーテッド 細胞増殖システムおよび使用方法
ES2665024T3 (es) * 2007-03-05 2018-04-24 Terumo Bct, Inc. Métodos para controlar el movimiento celular en biorreactores de fibra hueca
JP5524824B2 (ja) * 2007-04-06 2014-06-18 テルモ ビーシーティー、インコーポレーテッド 改良されたバイオリアクタ表面
WO2008128165A2 (en) * 2007-04-13 2008-10-23 Caridianbct, Inc. Cell expansion system and methods of use
EP2566951B1 (de) 2010-05-05 2020-03-04 Terumo BCT, Inc. Verfahren zur neuaussaat von in einem hohlfaser-bioreaktorsystem gezüchteten adhärenten zellen
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
WO2012171026A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Methods for high yield virus production
DE102011106914B4 (de) 2011-07-08 2015-08-27 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen
AU2012327878A1 (en) 2011-10-28 2014-05-29 Patrys Limited PAT-LM1 epitopes and methods for using same
CN104540933A (zh) 2012-08-20 2015-04-22 泰尔茂比司特公司 在细胞扩增系统的生物反应器中加载和分配细胞的方法
EP2909302A4 (de) 2012-08-28 2016-07-27 Biovest Int Inc Bioherstellungssuite und verfahren zur herstellung grosser mengen von zellen, viren und biomolekülen
WO2014036488A1 (en) 2012-08-31 2014-03-06 Biovest International, Inc. Methods for producing high-fidelity autologous idiotype vaccines
WO2014117220A1 (en) 2013-02-01 2014-08-07 Transbio Ltd Anti-cd83 antibodies and use thereof
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
US10077421B2 (en) 2014-04-24 2018-09-18 Terumo Bct, Inc. Measuring flow rate
EP3198006B1 (de) 2014-09-26 2021-03-24 Terumo BCT, Inc. Geplante fütterung
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515894A (en) * 1979-03-20 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human T cells
US4515895A (en) * 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human helper T cells
US4515893A (en) * 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
JPS5642584A (en) * 1979-09-18 1981-04-20 Asahi Chem Ind Co Ltd Cell cultivation method
US4364932A (en) * 1979-09-18 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to human cytotoxic and suppressor T cells and methods of preparing same
US4444887A (en) * 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4464355A (en) * 1981-03-26 1984-08-07 Hooper Trading Co. Serum-free and mitogen-free T-cell growth factor and process for making same
US4401756A (en) * 1981-04-14 1983-08-30 Immunex Corporation Process for preparing human interleukin 2
US4473642A (en) * 1981-04-29 1984-09-25 Immunex Corporation Constitutive production of interleukin 2 by a T cell hybridoma
US4407945A (en) * 1981-04-29 1983-10-04 Immunex Corporation Constitutive production of interleukin 2 by a T cell hybridoma
US4544632A (en) * 1981-06-12 1985-10-01 Yuichi Yamamura Human T cell lines and method of producing same
US4404280A (en) * 1981-07-16 1983-09-13 Steven Gillis Process for preparing murine interleukin 2 in the presence of interleukin 1 from an interleukin 2 nonproducer malignant cell line and cell line therefor
US4490289A (en) * 1982-09-16 1984-12-25 Hoffmann-La Roche Inc. Homogeneous human interleukin 2
JPS60137284A (ja) * 1983-12-23 1985-07-20 Sumitomo Chem Co Ltd 抗体産生細胞の取得方法、及びそれを用いた抗体の製造方法
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
JPS61280270A (ja) * 1985-06-03 1986-12-10 Teijin Ltd 細胞培養装置
US4690915A (en) * 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans

Also Published As

Publication number Publication date
JP2529321B2 (ja) 1996-08-28
DE3782736D1 (de) 1992-12-24
EP0302894A4 (de) 1989-02-06
US5541105A (en) 1996-07-30
EP0302894A1 (de) 1989-02-15
WO1987006610A1 (en) 1987-11-05
DE3782736T2 (de) 1993-06-09
US5631006A (en) 1997-05-20
JPH01502315A (ja) 1989-08-17
EP0302894B1 (de) 1992-11-19

Similar Documents

Publication Publication Date Title
ATE82588T1 (de) Zuchtverfahren fuer leukocyten.
FR2605185B1 (fr) Procede de culture des plantes
ATE85361T1 (de) Molekulare zuechtung.
ATE31549T1 (de) Verfahren zur zuechtung von zellkulturen.
EP0270615A4 (de) TRANSFORMATION UND EXPRESSION EINES FREMDEN GENS IN -i(BRASSICA) SPEZIES.
EP0283942A3 (en) Basal nutrient medium for cell culture
DE68914582D1 (de) Endothelin-DNA und ihre Verwendung.
NO872395D0 (no) Fremgangsmaate for fremstilling av biologisk aktiv plasminogenaktivator.
ATE67787T1 (de) Verfahren zur herstellung von proteinen mittels induzierbarer expressionssysteme in in-vivovermehrten, genetisch modifizierten eukaryotischen wirtszellen.
BG49719A3 (bg) Метод за получаване на варианти на хирудина и приложението им
RU94045882A (ru) Способ получения нового типа растений с азотфиксирующей способностью в листьях
ATE15693T1 (de) Zellkultur-verfahren.
ES8601300A1 (es) Procedimiento para preparar celulas de cultivo en suspension de plantas de girasol.
ES2043610T3 (es) Procedimiento para la produccion de un polipeptido hibrido del tipo activador de plasminogeno.
FR2396083A1 (fr) Procede de culture de virus
IT1228210B (it) Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali.
DE3666458D1 (en) Method and device for the _i(in vitro) culture of plant cells and organs, as well as for the micropropagation and regeneration of complete plants
IT1114284B (it) Procedimento per mantenere attiva la cultura di fermenti
IT8567141A0 (it) Procedimento per la coltura di cellule mediante dispersione di gas
BG44029A3 (en) Method for preparing of n- dimethyl morphinanic derivatives
DE3669826D1 (de) Schutz von nutzpflanzenkulturen vor boden- und samenbuertigen pflanzenkrankheiten durch saatgutbehandlung mit mikroorganismen-kulturen.
FR2595902B1 (fr) Bac de semis et de culture de plantes et procede de realisation
EP0299067A4 (de) Zuchtmedium für pflanzen.
Lalitha et al. Culture and phagocytic characteristics of Schwann cells in vitro. A possible model substrate for cultivation of M. leprae
FR2572251B3 (fr) Dispositif pour la culture de plantes