ATE83376T1 - Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten. - Google Patents
Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten.Info
- Publication number
- ATE83376T1 ATE83376T1 AT87902015T AT87902015T ATE83376T1 AT E83376 T1 ATE83376 T1 AT E83376T1 AT 87902015 T AT87902015 T AT 87902015T AT 87902015 T AT87902015 T AT 87902015T AT E83376 T1 ATE83376 T1 AT E83376T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrazoles
- treatment
- medication
- hypersensitive
- quinolinyl ether
- Prior art date
Links
- KJUGUADJHNHALS-UHFFFAOYSA-N 1H-tetrazole Substances C=1N=NNN=1 KJUGUADJHNHALS-UHFFFAOYSA-N 0.000 title abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 title abstract 2
- -1 QUINOLINYL ETHER TETRAZOLES Chemical class 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- GSUKVTZXJFHNEU-UHFFFAOYSA-N 2-quinolin-2-yloxyquinoline Chemical compound C1=CC=CC2=NC(OC=3N=C4C=CC=CC4=CC=3)=CC=C21 GSUKVTZXJFHNEU-UHFFFAOYSA-N 0.000 abstract 1
- 239000000867 Lipoxygenase Inhibitor Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/20—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D309/22—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/839,410 US4839369A (en) | 1985-04-16 | 1986-03-13 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
| US06/911,028 US4868193A (en) | 1986-09-24 | 1986-09-24 | Styryl tetrazoles and anti-allergic use thereof |
| PCT/US1987/000560 WO1987005510A1 (en) | 1986-03-13 | 1987-03-11 | Quinolinyl ether or thioether tetrazoles as agents for the treatment of hypersensitive ailments |
| EP87902015A EP0260305B1 (de) | 1986-03-13 | 1987-03-11 | Chinolinyläther tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE83376T1 true ATE83376T1 (de) | 1993-01-15 |
Family
ID=27126105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87902015T ATE83376T1 (de) | 1986-03-13 | 1987-03-11 | Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0260305B1 (de) |
| JP (1) | JPS63503139A (de) |
| AT (1) | ATE83376T1 (de) |
| AU (1) | AU612569B2 (de) |
| CA (1) | CA1324142C (de) |
| DE (1) | DE3783105T2 (de) |
| WO (1) | WO1987005510A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4962203A (en) * | 1985-06-18 | 1990-10-09 | Merck Frost Canada, Inc. | 2-substituted quinolines useful as leukotriene antagonists |
| MA20977A1 (fr) * | 1986-05-19 | 1987-12-31 | Ciba Geigy Ag | Plantes tolerant les herbicides contenant le gene de gluthathione S-Transferase |
| EP0271287A3 (de) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Chinolindicarbonsäuren und ihre Amide |
| US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920133A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US5104882A (en) * | 1987-11-25 | 1992-04-14 | Merck Frosst Canada, Inc. | Diarylstrylquinoline diacids and pharmaceutical compositions thereof |
| US5204358A (en) * | 1987-11-25 | 1993-04-20 | Merck Frosst Canada, Inc. | Hetaryl styryl quinolines as leukotriene inhibitors |
| EP0318093A3 (de) * | 1987-11-25 | 1990-12-05 | Merck Frosst Canada Inc. | Diarylchinolindicarbonsäure und ihre Verwendung als Arzneimittel |
| US5232916A (en) * | 1988-06-27 | 1993-08-03 | Merck Frosst Canada, Inc. | Quinoline ether alkanoic acids |
| NZ229761A (en) * | 1988-07-12 | 1991-10-25 | Ici Pharma | Substituted thiazole derivatives for use as inhibitors of enzyme 5-lipoxygenase; pharmaceutical compositions and preparatory processes |
| US5089495A (en) * | 1989-01-30 | 1992-02-18 | Imperial Chemical Industries Plc | Heterocyclic thiazole derivatives and pharmaceutical compositions comprising said derivatives |
| EP0412848B1 (de) * | 1989-08-11 | 1995-01-18 | Zeneca Limited | Chinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
| FR2665159B1 (fr) * | 1990-07-24 | 1992-11-13 | Rhone Poulenc Sante | Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| US5246944A (en) * | 1991-08-13 | 1993-09-21 | Merck & Co., Inc. | Quinoline angiotensin ii antagonists incorporating a substituted benzyl element |
| DE4129742A1 (de) * | 1991-09-06 | 1993-03-11 | Bayer Ag | Heterocyclisch substituierte chinolylmethoxy-phenylacetamide |
| YU72201A (sh) * | 1999-04-28 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | Derivati di-aril kiseline kao ppar receptorski ligandi |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4202985A (en) * | 1978-10-25 | 1980-05-13 | E. R. Squibb & Sons, Inc. | Imidazolylethoxy derivatives of quinoline-3-methanols |
| DE3275295D1 (en) * | 1981-11-12 | 1987-03-05 | Fisons Plc | Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them |
| US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
| US4661499A (en) * | 1985-06-18 | 1987-04-28 | Merck Frosst Canada, Inc. | 2-[(substituted)-phenoxymethyl]quinolines |
-
1987
- 1987-03-11 JP JP62501942A patent/JPS63503139A/ja active Pending
- 1987-03-11 AU AU71623/87A patent/AU612569B2/en not_active Ceased
- 1987-03-11 EP EP87902015A patent/EP0260305B1/de not_active Expired - Lifetime
- 1987-03-11 WO PCT/US1987/000560 patent/WO1987005510A1/en not_active Ceased
- 1987-03-11 DE DE8787902015T patent/DE3783105T2/de not_active Expired - Fee Related
- 1987-03-11 AT AT87902015T patent/ATE83376T1/de active
- 1987-03-13 CA CA000532055A patent/CA1324142C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0260305A4 (de) | 1988-07-04 |
| DE3783105T2 (de) | 1993-04-22 |
| CA1324142C (en) | 1993-11-09 |
| JPS63503139A (ja) | 1988-11-17 |
| EP0260305A1 (de) | 1988-03-23 |
| AU612569B2 (en) | 1991-07-18 |
| EP0260305B1 (de) | 1992-12-16 |
| DE3783105D1 (de) | 1993-01-28 |
| AU7162387A (en) | 1987-10-09 |
| WO1987005510A1 (en) | 1987-09-24 |
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