ATE83378T1 - Verwendung von 3'-azido-deoxythymidin zur herstellung eines arzneimittels zur behandlung von humanen brustcarzinomen. - Google Patents

Verwendung von 3'-azido-deoxythymidin zur herstellung eines arzneimittels zur behandlung von humanen brustcarzinomen.

Info

Publication number: ATE83378T1
Authority: AT; Austria
Prior art keywords: deoxythymidine; azido; treatment; medication; manufacture
Prior art date: 1988-01-07

Application number

AT89300099T

Other languages

English (en)

Inventor

Charles Anthony Hart

Kevin Mccarthy

Samuel John Leinster

Christopher Douglas Green

Ayad Mohamed Khala Al-Sumidaie

Original Assignee

Univ Liverpool

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-07

Filing date

1989-01-06

Publication date

1993-01-15

1989-01-06 Application filed by Univ Liverpool filed Critical Univ Liverpool

1993-01-15 Application granted granted Critical

1993-01-15 Publication of ATE83378T1 publication Critical patent/ATE83378T1/de

Links

206010006187 Breast cancer Diseases 0.000 title abstract 2
208000026310 Breast neoplasm Diseases 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
UJQBOUAGWGVOTI-XSSZXYGBSA-N 1-[(2r,4s,5r)-4-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@](O)(N=[N+]=[N-])C1 UJQBOUAGWGVOTI-XSSZXYGBSA-N 0.000 title 1
201000008275 breast carcinoma Diseases 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
201000009030 Carcinoma Diseases 0.000 abstract 1
IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Natural products O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
239000003419 rna directed dna polymerase inhibitor Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)

AT89300099T 1988-01-07 1989-01-06 Verwendung von 3'-azido-deoxythymidin zur herstellung eines arzneimittels zur behandlung von humanen brustcarzinomen. ATE83378T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888800276A GB8800276D0 (en)	1988-01-07	1988-01-07	Medical treatment
EP89300099A EP0327200B1 (de)	1988-01-07	1989-01-06	Verwendung von 3'-Azido-deoxythymidin zur Herstellung eines Arzneimittels zur Behandlung von humanen Brustcarzinomen

Publications (1)

Publication Number	Publication Date
ATE83378T1 true ATE83378T1 (de)	1993-01-15

Family

ID=10629601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89300099T ATE83378T1 (de)	1988-01-07	1989-01-06	Verwendung von 3'-azido-deoxythymidin zur herstellung eines arzneimittels zur behandlung von humanen brustcarzinomen.

Country Status (15)

Country	Link
US (1)	US5223490A (de)
EP (1)	EP0327200B1 (de)
JP (1)	JP2761420B2 (de)
KR (1)	KR900700110A (de)
CN (1)	CN1034134A (de)
AT (1)	ATE83378T1 (de)
AU (1)	AU626284B2 (de)
CA (1)	CA1331138C (de)
DE (1)	DE68903840T2 (de)
DK (1)	DK173766B1 (de)
GB (1)	GB8800276D0 (de)
IE (1)	IE63788B1 (de)
MY (1)	MY104462A (de)
WO (1)	WO1989006132A1 (de)
ZA (1)	ZA8993B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8823353D0 (en) *	1988-10-05	1988-11-09	Wellcome Found	Therapeutic nucleosides
FR2649982B1 (fr) *	1989-07-20	1991-09-27	Inst Nat Sante Rech Med	Membrane biologique artificielle
US5405837A (en) *	1993-05-18	1995-04-11	Indiana University Foundation	Method for the treatment of neoplastic disease utilizing tiazofurin and ribavirin
US5576177A (en) *	1994-03-09	1996-11-19	St. Jude Children's Research Hospital	Bioassay for reverse transcriptase inhibitors
EP1174141A3 (de) *	1996-01-23	2003-04-23	ICN Pharmaceuticals, Inc.	Regulierung der TH1/TH2 Cytokinexpression durch Ribavirin and Ribavirinanaloge in activierten T-Lymphocyten
HUP0100433A3 (en) *	1997-12-22	2003-01-28	Schering Corp	Orally administrable solid ribavirin dosage forms and process for producing them
US7351542B2 (en)	2002-05-20	2008-04-01	The Regents Of The University Of California	Methods of modulating tubulin deacetylase activity
US20050203156A1 (en) *	2004-03-12	2005-09-15	Wyeth	Hydantoins having RNase modulatory activity
WO2005090299A2 (en) *	2004-03-12	2005-09-29	Wyeth	Carbamates as hiv anti-viral agents
WO2005090320A2 (en) *	2004-03-12	2005-09-29	Wyeth	Triazole derivatives and method of using the same to treat hiv infections
US7553967B2 (en) *	2004-03-12	2009-06-30	Wyeth	1,2-Dihydroquinoline derivatives and method for using the same to treat HIV infections
US8497292B2 (en)	2005-12-28	2013-07-30	Translational Therapeutics, Inc.	Translational dysfunction based therapeutics
WO2007123579A2 (en) *	2005-12-28	2007-11-01	Translational Therapeutics	Translational dysfunction based therapeutics
US7725227B2 (en) *	2006-12-15	2010-05-25	Gm Global Technology Operations, Inc.	Method, system, and apparatus for providing enhanced steering pull compensation
WO2022066882A1 (en) *	2020-09-23	2022-03-31	Oncolinea Pharmaceuticals, Inc.	Method for treating cancer with a reverse transcriptase inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8506869D0 (en) *	1985-03-16	1985-04-17	Wellcome Found	Antiviral compound
IE73219B1 (en) *	1985-03-16	1997-05-07	Wellcome Found	Therapeutic nucleosides
WO1987001284A1 (en) *	1985-08-26	1987-03-12	United States Of America, Represented By The Unite	Inhibition of in vitro infectivity and cytopathic effect of htlv-iii/lav by 2',3'-dideoxynosine, 2',3'-dideoxyguanosine, or 2',3'-dideoxyadenosine
DD251984A5 (de) *	1985-09-17	1987-12-02	The Wellcome Foundation Limited,Gb	Verfahren zur herstellung von 3'-azidonucleosiden und pharmazeutisch vertraeglichen derivaten davon

1988
- 1988-01-07 GB GB888800276A patent/GB8800276D0/en active Pending
1989
- 1989-01-04 MY MYPI89000008A patent/MY104462A/en unknown
- 1989-01-04 CA CA000587506A patent/CA1331138C/en not_active Expired - Fee Related
- 1989-01-05 ZA ZA8993A patent/ZA8993B/xx unknown
- 1989-01-06 JP JP1501527A patent/JP2761420B2/ja not_active Expired - Lifetime
- 1989-01-06 WO PCT/GB1989/000010 patent/WO1989006132A1/en not_active Ceased
- 1989-01-06 AU AU29498/89A patent/AU626284B2/en not_active Ceased
- 1989-01-06 AT AT89300099T patent/ATE83378T1/de active
- 1989-01-06 EP EP89300099A patent/EP0327200B1/de not_active Expired - Lifetime
- 1989-01-06 US US07/536,669 patent/US5223490A/en not_active Expired - Lifetime
- 1989-01-06 IE IE3689A patent/IE63788B1/en not_active IP Right Cessation
- 1989-01-06 DE DE8989300099T patent/DE68903840T2/de not_active Expired - Lifetime
- 1989-01-06 KR KR1019890701666A patent/KR900700110A/ko not_active Withdrawn
- 1989-01-07 CN CN89100192A patent/CN1034134A/zh active Pending
1990
- 1990-07-05 DK DK199001621A patent/DK173766B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1034134A (zh)	1989-07-26
CA1331138C (en)	1994-08-02
IE63788B1 (en)	1995-06-14
IE890036L (en)	1989-07-07
DK162190D0 (da)	1990-07-05
AU626284B2 (en)	1992-07-30
DK173766B1 (da)	2001-09-24
EP0327200A1 (de)	1989-08-09
JP2761420B2 (ja)	1998-06-04
DK162190A (da)	1990-07-05
MY104462A (en)	1994-04-30
ZA8993B (en)	1989-10-25
EP0327200B1 (de)	1992-12-16
GB8800276D0 (en)	1988-02-10
WO1989006132A1 (en)	1989-07-13
DE68903840D1 (de)	1993-01-28
DE68903840T2 (de)	1993-06-17
US5223490A (en)	1993-06-29
KR900700110A (ko)	1990-08-11
AU2949889A (en)	1989-08-01
JPH03503049A (ja)	1991-07-11

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