ATE84706T1 - Spheroiden. - Google Patents

Spheroiden.

Info

Publication number: ATE84706T1
Authority: AT; Austria
Prior art keywords: release; hours; film coated; alkylxanthine; spheroids
Prior art date: 1986-12-02

Application number

AT87310427T

Other languages

English (en)

Inventor

Stewart Thomas Leslie

Sandra Therese Antoi Malkowska

Joanne Marchant

Philip John Neale

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-02

Filing date

1987-11-26

Publication date

1993-02-15

1987-11-26 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

1993-02-15 Application granted granted Critical

1993-02-15 Publication of ATE84706T1 publication Critical patent/ATE84706T1/de

Links

XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
239000003795 chemical substances by application Substances 0.000 abstract 2
ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical group O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
239000012062 aqueous buffer Substances 0.000 abstract 1
238000013270 controlled release Methods 0.000 abstract 1
238000004090 dissolution Methods 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
239000008108 microcrystalline cellulose Substances 0.000 abstract 1
229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229960000278 theophylline Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT87310427T 1986-12-02 1987-11-26 Spheroiden. ATE84706T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB868628728A GB8628728D0 (en)	1986-12-02	1986-12-02	Spheroids
EP87310427A EP0270305B1 (de)	1986-12-02	1987-11-26	Spheroiden

Publications (1)

Publication Number	Publication Date
ATE84706T1 true ATE84706T1 (de)	1993-02-15

Family

ID=10608274

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87310427T ATE84706T1 (de)	1986-12-02	1987-11-26	Spheroiden.

Country Status (12)

Country	Link
US (1)	US4844910A (de)
EP (1)	EP0270305B1 (de)
JP (1)	JP2568230B2 (de)
AT (1)	ATE84706T1 (de)
AU (1)	AU596249B2 (de)
CA (1)	CA1296254C (de)
DE (1)	DE3783739T2 (de)
DK (1)	DK630287A (de)
ES (1)	ES2053567T3 (de)
GB (1)	GB8628728D0 (de)
IE (1)	IE59942B1 (de)
ZA (1)	ZA878601B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8813064D0 (en) *	1988-06-02	1988-07-06	Euro Celtique Sa	Controlled release dosage forms having defined water content
CA2007055A1 (en) *	1989-01-06	1990-07-06	Garth Boehm	Theophylline dosage form
US5202128A (en) *	1989-01-06	1993-04-13	F. H. Faulding & Co. Limited	Sustained release pharmaceutical composition
US5196203A (en) *	1989-01-06	1993-03-23	F. H. Faulding & Co. Limited	Theophylline dosage form
DE3929864A1 (de) *	1989-09-08	1991-03-14	Nordmark Arzneimittel Gmbh	Verfahren zur herstellung von theophyllin-pellets
EP0418596A3 (en) *	1989-09-21	1991-10-23	American Cyanamid Company	Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
EP0418597A3 (en) *	1989-09-21	1991-11-27	American Cyanamid Company	Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
SE9002017D0 (sv) *	1990-06-06	1990-06-06	Kabivitrum Ab	Process for manufacture of matrices
GB9016885D0 (en) *	1990-08-01	1990-09-12	Scras	Sustained release pharmaceutical compositions
US5160742A (en) *	1991-12-31	1992-11-03	Abbott Laboratories	System for delivering an active substance for sustained release
SE9301220D0 (sv) *	1993-04-14	1993-04-14	Kabi Pharmacia Ab	Manufacturing matrices
US5569467A (en) *	1993-05-15	1996-10-29	Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.)	Process for the preparation of microballs and microballs thus obtained
US5413690A (en) *	1993-07-23	1995-05-09	Boehringer Mannheim Corporation	Potentiometric biosensor and the method of its use
US5945125A (en) *	1995-02-28	1999-08-31	Temple University	Controlled release tablet
US6375957B1 (en)	1997-12-22	2002-04-23	Euro-Celtique, S.A.	Opioid agonist/opioid antagonist/acetaminophen combinations
JP2001526228A (ja)	1997-12-22	2001-12-18	ユーロ−セルティーク，エス．エイ．	オピオイド作動薬／拮抗薬の併用
CA2314896C (en) *	1997-12-22	2005-09-13	Euro-Celtique, S.A.	A method of preventing abuse of opioid dosage forms
HU229705B1 (en)	2000-02-08	2014-05-28	Euro Celtique Sa	Tamper-resistant oral opioid agonist formulations
GB0025208D0 (en)	2000-10-13	2000-11-29	Euro Celtique Sa	Delayed release pharmaceutical formulations
CN1525851A (zh)	2001-05-11	2004-09-01	��ҩ��޹�˾	抗滥用阿片样物质控释剂型
SI1416842T1 (sl)	2001-07-18	2009-06-30	Euro Celtique Sa	Farmacevtske kombinacije oksikodona in naloksona
ATE431738T1 (de)	2001-08-06	2009-06-15	Euro Celtique Sa	Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist
AU2002324624A1 (en)	2001-08-06	2003-02-24	Euro-Celtique S.A.	Sequestered antagonist formulations
US20030044458A1 (en)	2001-08-06	2003-03-06	Curtis Wright	Oral dosage form comprising a therapeutic agent and an adverse-effect agent
EP1492505B1 (de)	2002-04-05	2015-06-03	Euro-Celtique S.A.	Pharmazeutische zubereitung enthaltend oxycodon und naloxon
KR100628263B1 (ko) *	2002-08-21	2006-09-27	엘지.필립스 엘시디 주식회사	액정표시소자
US7815934B2 (en)	2002-09-20	2010-10-19	Alpharma Pharmaceuticals, Llc	Sequestering subunit and related compositions and methods
US20040202717A1 (en)	2003-04-08	2004-10-14	Mehta Atul M.	Abuse-resistant oral dosage forms and method of use thereof
MY135852A (en)	2003-04-21	2008-07-31	Euro Celtique Sa	Pharmaceutical products
US8802139B2 (en)	2003-06-26	2014-08-12	Intellipharmaceutics Corp.	Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
EP1604666A1 (de)	2004-06-08	2005-12-14	Euro-Celtique S.A.	Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
US8394409B2 (en)	2004-07-01	2013-03-12	Intellipharmaceutics Corp.	Controlled extended drug release technology
US10624858B2 (en)	2004-08-23	2020-04-21	Intellipharmaceutics Corp	Controlled release composition using transition coating, and method of preparing same
EP1848292B1 (de) *	2005-02-04	2015-10-14	Philip Morris Products S.A.	Zigarette und filter mit cellulosischem geschmackszusatz
EP1702558A1 (de) *	2005-02-28	2006-09-20	Euro-Celtique S.A.	Verfahren und Vorrichtung zur Darmtätigkeitserfassung
US10064828B1 (en)	2005-12-23	2018-09-04	Intellipharmaceutics Corp.	Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP5457830B2 (ja) *	2006-04-03	2014-04-02	オディディ，イサ	オルガノゾル被膜を含む制御放出送達デバイス
US10960077B2 (en)	2006-05-12	2021-03-30	Intellipharmaceutics Corp.	Abuse and alcohol resistant drug composition
SI2719378T1 (sl)	2006-06-19	2016-11-30	Alpharma Pharmaceuticals Llc	Farmacevtski sestavki
US8623418B2 (en)	2007-12-17	2014-01-07	Alpharma Pharmaceuticals Llc	Pharmaceutical composition
MY152279A (en)	2009-03-10	2014-09-15	Euro Celtique Sa	Immediate release pharmaceutical compositions comprising oxycodone and naloxone
US10071089B2 (en)	2013-07-23	2018-09-11	Euro-Celtique S.A.	Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
CN105193738B (zh) *	2015-09-21	2018-09-04	珠海市东辰制药有限公司	一种微晶纤维素丸芯的制备工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3492397A (en) *	1967-04-07	1970-01-27	Warner Lambert Pharmaceutical	Sustained release dosage in the pellet form and process thereof
US3576759A (en) *	1968-04-12	1971-04-27	Ncr Co	Process for en masse production of spherules by desiccation
US3965256A (en) *	1972-05-16	1976-06-22	Synergistics	Slow release pharmaceutical compositions
JPS56122311A (en) *	1980-02-29	1981-09-25	Eisai Co Ltd	Lasting theophylline pharmaceutical composition
US4587118A (en) *	1981-07-15	1986-05-06	Key Pharmaceuticals, Inc.	Dry sustained release theophylline oral formulation
FR2535202B1 (fr) *	1982-11-03	1985-08-09	Fabre Sa Pierre	Comprimes de theophylline a liberation controlee et leur procede de fabrication
HU187215B (en) *	1983-01-26	1985-11-28	Egyt Gyogyszervegyeszeti Gyar	Method for producing pharmaceutical product of high actor content and prolonged effect
DE3306250A1 (de) *	1983-02-23	1984-08-23	Basf Ag, 6700 Ludwigshafen	Sphaerische einkristalle fuer pharmazeutische zwecke
IE55745B1 (en) *	1983-04-06	1991-01-02	Elan Corp Plc	Sustained absorption pharmaceutical composition
ATE29392T1 (de) *	1983-06-22	1987-09-15	Univ Ohio State Res Found	Herstellung eines feinteiligen materials und verkapselung.
IE58246B1 (en) *	1984-12-21	1993-08-11	Byk Gulden Lomberg Chem Fab	Theophylline sustained release formulation
ZA859645B (en) *	1984-12-21	1986-08-27	Byk Gulden Lomberg Chem Fab	Theophylline sustained release formulation
EP0222883A1 (de) *	1985-05-15	1987-05-27	Riker Laboratories, Inc.	Theophyllinarzneimittel mit verzögerter freigabe sowie verfahren zu deren herstellung
GB8628359D0 (en) *	1986-11-27	1986-12-31	Zyma Sa	Galenical formulation

1986
- 1986-12-02 GB GB868628728A patent/GB8628728D0/en active Pending
1987
- 1987-11-17 ZA ZA878601A patent/ZA878601B/xx unknown
- 1987-11-18 IE IE310587A patent/IE59942B1/en not_active IP Right Cessation
- 1987-11-19 US US07/122,747 patent/US4844910A/en not_active Expired - Lifetime
- 1987-11-26 AT AT87310427T patent/ATE84706T1/de not_active IP Right Cessation
- 1987-11-26 EP EP87310427A patent/EP0270305B1/de not_active Expired - Lifetime
- 1987-11-26 ES ES87310427T patent/ES2053567T3/es not_active Expired - Lifetime
- 1987-11-26 DE DE8787310427T patent/DE3783739T2/de not_active Expired - Lifetime
- 1987-11-30 CA CA000553129A patent/CA1296254C/en not_active Expired - Fee Related
- 1987-12-01 DK DK630287A patent/DK630287A/da not_active Application Discontinuation
- 1987-12-01 JP JP62304397A patent/JP2568230B2/ja not_active Expired - Lifetime
- 1987-12-02 AU AU81997/87A patent/AU596249B2/en not_active Ceased

Also Published As

Publication number	Publication date
DE3783739D1 (en)	1993-03-04
CA1296254C (en)	1992-02-25
AU8199787A (en)	1988-06-02
IE59942B1 (en)	1994-05-04
ZA878601B (en)	1988-05-11
DK630287A (da)	1988-06-03
EP0270305B1 (de)	1993-01-20
JPS63154620A (ja)	1988-06-27
US4844910A (en)	1989-07-04
AU596249B2 (en)	1990-04-26
JP2568230B2 (ja)	1996-12-25
IE873105L (en)	1988-06-02
ES2053567T3 (es)	1994-08-01
GB8628728D0 (en)	1987-01-07
DK630287D0 (da)	1987-12-01
DE3783739T2 (de)	1993-05-13
EP0270305A2 (de)	1988-06-08
EP0270305A3 (en)	1990-10-10

Legal Events

Date	Code	Title	Description
1993-07-15	UEP	Publication of translation of european patent specification
2003-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE84706T1 (de)	1993-02-15	Spheroiden.
DE3750145D1 (de)	1994-08-04	Zusammensetzung mit kontrollierter Freisetzung von Dihydrocodein.
ATE67933T1 (de)	1991-10-15	Hydromorphon-zusammensetzung mit gesteuerter wirkstofffreisetzung.
KR0136279B1 (ko)	1998-04-25	일정수분을 함유하는 서방형 제제
BE901359A (fr)	1985-04-16	Composition pharmaceutique a absorption reglee.
BE901328A (fr)	1985-04-16	Composition pharmaceutique a absorption reglee.
EP0377517A3 (de)	1990-10-24	Theophyllin-Dosisform
NZ216622A (en)	1988-05-30	Solid, stable dosage forms with an elastic film coating which decomposes in aqueous solution
ATE241987T1 (de)	2003-06-15	Diltiazem-zusammensetzungen mit kontrollierter wirkstoffabsorption
YU20050411A (sh)	2006-08-17	Komopzicije oksikodona sa kontrolisanim oslobadanjem
YU20050410A (sh)	2006-05-25	Kompozicije oksikodona sa kontrolisanim oslobađanjem