ATE85078T1 - Regulierung von gen-expression durch translationshemmung unter verwendung von m-rns hinderndem komplementaer-rns. - Google Patents

Regulierung von gen-expression durch translationshemmung unter verwendung von m-rns hinderndem komplementaer-rns.

Info

Publication number
ATE85078T1
ATE85078T1 AT84112647T AT84112647T ATE85078T1 AT E85078 T1 ATE85078 T1 AT E85078T1 AT 84112647 T AT84112647 T AT 84112647T AT 84112647 T AT84112647 T AT 84112647T AT E85078 T1 ATE85078 T1 AT E85078T1
Authority
AT
Austria
Prior art keywords
rna
regulation
gene expression
translation inhibition
inhibiting complementary
Prior art date
Application number
AT84112647T
Other languages
English (en)
Inventor
Masayori Inouye
Takeshi Mizuno
Mei-Yin Chou
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Priority claimed from EP84112647A external-priority patent/EP0140308B2/de
Application granted granted Critical
Publication of ATE85078T1 publication Critical patent/ATE85078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
AT84112647T 1983-10-20 1984-10-19 Regulierung von gen-expression durch translationshemmung unter verwendung von m-rns hinderndem komplementaer-rns. ATE85078T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54352883A 1983-10-20 1983-10-20
US58528284A 1984-03-01 1984-03-01
EP84112647A EP0140308B2 (de) 1983-10-20 1984-10-19 Regulierung von Gen-Expression durch Translationshemmung unter Verwendung von m-RNS hinderndem Komplementär-RNS

Publications (1)

Publication Number Publication Date
ATE85078T1 true ATE85078T1 (de) 1993-02-15

Family

ID=27226930

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84112647T ATE85078T1 (de) 1983-10-20 1984-10-19 Regulierung von gen-expression durch translationshemmung unter verwendung von m-rns hinderndem komplementaer-rns.

Country Status (1)

Country Link
AT (1) ATE85078T1 (de)

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