ATE85796T1 - Antiparasit-derivate. - Google Patents

Antiparasit-derivate.

Info

Publication number: ATE85796T1
Authority: AT; Austria
Prior art keywords: alkyl; substituted; double bond; group; absent
Prior art date: 1987-11-14

Application number

AT88310458T

Other languages

English (en)

Inventor

Christopher James Dr Dutton

Shih-Jen Edward Dr Lee

Stephen Paul Dr Gibson

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-14

Filing date

1988-11-07

Publication date

1993-03-15

1988-11-07 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

1993-03-15 Application granted granted Critical

1993-03-15 Publication of ATE85796T1 publication Critical patent/ATE85796T1/de

Links

230000002141 anti-parasite Effects 0.000 title 1
125000005843 halogen group Chemical group 0.000 abstract 5
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
125000000081 (C5-C8) cycloalkenyl group Chemical group 0.000 abstract 2
125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 2
125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
239000005864 Sulphur Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
239000000642 acaricide Substances 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000005082 alkoxyalkenyl group Chemical group 0.000 abstract 1
125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
230000000507 anthelmentic effect Effects 0.000 abstract 1
239000000921 anthelmintic agent Substances 0.000 abstract 1
229940124339 anthelmintic agent Drugs 0.000 abstract 1
239000003096 antiparasitic agent Substances 0.000 abstract 1
229940125687 antiparasitic agent Drugs 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000013057 ectoparasiticide Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000002917 insecticide Substances 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT88310458T 1987-11-14 1988-11-07 Antiparasit-derivate. ATE85796T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878726730A GB8726730D0 (en)	1987-11-14	1987-11-14	Antiparasitic agents
EP88310458A EP0317148B1 (de)	1987-11-14	1988-11-07	Antiparasit-Derivate

Publications (1)

Publication Number	Publication Date
ATE85796T1 true ATE85796T1 (de)	1993-03-15

Family

ID=10626990

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88310458T ATE85796T1 (de)	1987-11-14	1988-11-07	Antiparasit-derivate.

Country Status (10)

Country	Link
US (2)	US5702924A (de)
EP (1)	EP0317148B1 (de)
JP (1)	JP2854869B2 (de)
AT (1)	ATE85796T1 (de)
DE (1)	DE3878535T2 (de)
DK (1)	DK170343B1 (de)
ES (1)	ES2053764T3 (de)
GB (1)	GB8726730D0 (de)
IE (1)	IE61513B1 (de)
PT (1)	PT88991B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8813760D0 (en) *	1988-06-10	1988-07-13	American Cyanamid Co	Chemical process
GB8815967D0 (en) *	1988-07-05	1988-08-10	Pfizer Ltd	Antiparasitic agents
US5055454A (en) *	1989-10-30	1991-10-08	Merck & Co., Inc.	13-epi-avermectin derivatives useful as antiparasitic agents
US5192671A (en) *	1991-06-26	1993-03-09	Merck & Co., Inc.	Process for the glycosylation of avermectin compounds
GB9205007D0 (en) *	1992-03-07	1992-04-22	Pfizer Ltd	Antiparasitic agents
US6103504A (en) *	1992-03-25	2000-08-15	Pfizer Inc.	Process for production of avermectins and cultures therefor
GB9316129D0 (en) *	1993-08-04	1993-09-22	Pfizer Ltd	Antiprasatic agents
DE4427766A1 (de) *	1994-08-05	1996-02-08	Basf Ag	Verfahren zur Herstellung flüssigkristalliner Mischungen
AP1060A (en)	1998-01-02	2002-04-23	Pfizer Prod Inc	Novel erythromycin derivatives.
GB9825402D0 (en) *	1998-11-19	1999-01-13	Pfizer Ltd	Antiparasitic formulations
IL160619A0 (en)	2001-09-17	2004-07-25	Lilly Co Eli	Pesticidal formulations pesticidal formulations
US20120196821A1 (en)	2009-10-19	2012-08-02	Roger Mervyn Sargent	Method and formulation for the control of parasites

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE434277B (sv) *	1976-04-19	1984-07-16	Merck & Co Inc	Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) *	1977-04-11	1979-01-16	Merck & Co., Inc.	Carbohydrate derivatives of milbemycin and processes therefor
NZ186851A (en) *	1977-04-11	1984-12-14	Merck & Co Inc	Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4199569A (en) *	1977-10-03	1980-04-22	Merck & Co., Inc.	Selective hydrogenation products of C-076 compounds and derivatives thereof
PH15982A (en) *	1977-10-03	1983-05-18	Merck & Co Inc	Selective hydrogenation producta of c-076 compounds and derivatives thereof
IL56149A (en) *	1977-12-19	1989-09-28	Merck & Co Inc	13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4200581A (en) *	1978-08-04	1980-04-29	Merck & Co., Inc.	Alkyl derivatives of C-076 compounds
US4429042A (en) *	1978-09-08	1984-01-31	Merck & Co., Inc.	Strain of Streptomyces for producing antiparasitic compounds
US4328335A (en) *	1979-08-13	1982-05-04	Merck & Co., Inc.	Process for the interconversion of C-076 compounds
US4285963A (en) *	1980-08-07	1981-08-25	Merck & Co., Inc.	Novel derivatives of C-076 compounds
US4378353A (en) *	1981-02-17	1983-03-29	Merck & Co., Inc.	Novel C-076 compounds
US4333925A (en) *	1981-05-11	1982-06-08	Merck & Co., Inc.	Derivatives of C-076 compounds
US4423209A (en) *	1982-02-26	1983-12-27	Merck & Co., Inc.	Processes for the interconversion of avermectin compounds
CH666690A5 (de) *	1984-09-14	1988-08-15	Glaxo Group Ltd	Antibiotisch wirkende verbindungen der makrolidgruppe aus streptomyces-mikroorganismen, ihre herstellung und verwendung.
HUT39739A (en) *	1984-12-04	1986-10-29	Ciba Geigy Ag	Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB8502925D0 (en) *	1985-02-05	1985-03-06	Ici Plc	Macrocyclic lactones
IL78621A (en) *	1985-04-30	1991-06-30	American Cyanamid Co	Mylbemycin analogs,their preparation and pesticidal compositions containing them
ES8800986A1 (es) *	1985-07-27	1987-12-01	Pfizer	Un procedimiento para la produccion de un nuevo derivado de avermectina
EP0215654B1 (de) *	1985-09-13	1995-03-15	American Cyanamid Company	Makrolide Antibiotika und Verfahren zu deren Herstellung
EP0235085A1 (de) *	1986-02-20	1987-09-02	Ciba-Geigy Ag	13-Beta-Zuckerderivate von Milbemycinen, deren Herstellung und Verwendung gegen Ekto-und Endoparasiten am Nutztier oder an der Nutzpflanze
GB8606120D0 (en) *	1986-03-12	1986-04-16	Glaxo Group Ltd	Process
US4831016A (en) *	1986-10-31	1989-05-16	Merck & Co., Inc.	Reduced avermectin derivatives
JPH0725765B2 (ja) *	1987-03-17	1995-03-22	三共株式会社	抗生物質ミルベマイシン化合物およびその製造法
EP0319142B1 (de) *	1987-11-03	1994-04-06	Beecham Group Plc	Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung
CA1340771C (en) *	1987-11-09	1999-09-28	Shih-Jen Edward Lee	Ethylated avermectins
US5244879A (en) *	1992-03-18	1993-09-14	Merck & Co., Inc.	23-nor-23-oxa avermectin analogs are active anthelmintic agents

1987
- 1987-11-14 GB GB878726730A patent/GB8726730D0/en active Pending
1988
- 1988-11-07 AT AT88310458T patent/ATE85796T1/de not_active IP Right Cessation
- 1988-11-07 ES ES88310458T patent/ES2053764T3/es not_active Expired - Lifetime
- 1988-11-07 DE DE8888310458T patent/DE3878535T2/de not_active Expired - Fee Related
- 1988-11-07 EP EP88310458A patent/EP0317148B1/de not_active Expired - Lifetime
- 1988-11-10 DK DK627088A patent/DK170343B1/da not_active IP Right Cessation
- 1988-11-11 IE IE339988A patent/IE61513B1/en not_active IP Right Cessation
- 1988-11-11 PT PT88991A patent/PT88991B/pt not_active IP Right Cessation
- 1988-11-14 JP JP63287511A patent/JP2854869B2/ja not_active Expired - Fee Related
1991
- 1991-01-25 US US07/647,674 patent/US5702924A/en not_active Expired - Fee Related
1995
- 1995-06-05 US US08/465,625 patent/US6362168B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IE883399L (en)	1989-05-14
DE3878535T2 (de)	1993-06-03
US5702924A (en)	1997-12-30
EP0317148A3 (en)	1990-11-28
GB8726730D0 (en)	1987-12-16
US6362168B1 (en)	2002-03-26
JP2854869B2 (ja)	1999-02-10
DE3878535D1 (de)	1993-03-25
EP0317148B1 (de)	1993-02-17
DK627088D0 (da)	1988-11-10
ES2053764T3 (es)	1994-08-01
IE61513B1 (en)	1994-11-16
DK627088A (da)	1989-06-22
JPH01160983A (ja)	1989-06-23
PT88991B (pt)	1993-02-26
DK170343B1 (da)	1995-08-07
EP0317148A2 (de)	1989-05-24
PT88991A (pt)	1988-12-01

Legal Events

Date	Code	Title	Description
2005-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ZA793993B (en)	1981-03-25	Alkyl derivatives of c-076 compounds
IE37638B1 (en)	1977-09-14	Herbicidal compositions containing 4-phenoxy-phenoxy-propionic acid derivatives
DE3878535D1 (de)	1993-03-25	Antiparasit-derivate.
BR8800374A (pt)	1988-09-20	Composicoes fungicida derivado de acido,amida de acido,hidrazida de acido,processos para a preparacao de derivados de acido,para a preparacao de uma composicao e para o combate ou inibicao de uma infestacao e emprego
MY105950A (en)	1995-02-28	4-acyloxyquinoline derivatives and insecticidal or acaricidal compositions containing same.
ATE155792T1 (de)	1997-08-15	Ungesatigte 17-beta-substituierte-3-carboxy steroide
SE7710395L (sv)	1978-03-18	Bekempningsmedel mot skadegorare
ES397598A1 (es)	1975-04-01	Procedimiento para preparar compuestos organicos de azufre.
ES444870A1 (es)	1977-09-01	Procedimiento para preparar derivados de oxadiazolinona.
ES403303A1 (es)	1975-05-01	Procedimiento para la preparacion de agentes pesticidas.
SE8103471L (sv)	1981-12-04	Nya kinoxalin-2-yl-etenyl-ketoner jemte sett for deras framstellning
DK140782A (da)	1982-09-28	Antimikrobielle triazolderivater
EP0308145A3 (de)	1990-11-22	Mylbemycin-Derivate mit antiparasitärer Wirkung
ES8500269A1 (es)	1984-10-01	Procedimiento para la fabricacion de un derivado de azolcarboxamida n,n-subsitutida.
ATE11221T1 (de)	1985-02-15	Antibaktierielle zusammensetzungen, die eine beta-lactam-verbindung und eine 3-substituiertes propenoat enthalten.
GB1340889A (en)	1973-12-19	Pesticidal phosphorus-containing barbiturates
ES8206485A1 (es)	1982-08-16	Procedimiento para la obtencion de derivados pirazolicos de la oximinociano-acetamida de efecto fungicida.
GB1337269A (en)	1973-11-14	Phosphorus and thiophosphorus acid ester derivatives of substituted hydantoins
IE38834L (en)	1974-08-09	Fungicidal agents
ES452592A1 (es)	1977-11-16	Procedimiento para preparar esteres organicos de acidos fos-foricos.
ES8802413A1 (es)	1988-06-01	Procedimiento para preparar una composicion herbicida a base de carbamoiloxi-fenilcarbamato y aceite mineral de petroleo
ES452591A1 (es)	1977-11-16	Procedimiento para preparar esteres organicos de acidos fos-foricos.
GB1094977A (en)	1967-12-13	Oxadiazolone compounds
GB1358183A (en)	1974-06-26	Organic phosphorus pesticides
GB1109141A (en)	1968-04-10	Lincosamine derivatives