ATE89567T1 - Konjugate von vinblastin und seine derivate, verfahren zur herstellung derselben und diese konjugate enthaltende pharmazeutische zusammensetzungen. - Google Patents
Konjugate von vinblastin und seine derivate, verfahren zur herstellung derselben und diese konjugate enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE89567T1 ATE89567T1 AT86870042T AT86870042T ATE89567T1 AT E89567 T1 ATE89567 T1 AT E89567T1 AT 86870042 T AT86870042 T AT 86870042T AT 86870042 T AT86870042 T AT 86870042T AT E89567 T1 ATE89567 T1 AT E89567T1
- Authority
- AT
- Austria
- Prior art keywords
- conjugates
- vinblastine
- image
- derivatives
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid
Landscapes
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU86157A LU86157A1 (fr) | 1985-11-12 | 1985-11-12 | Nouveau procede de fabrication de conjugues de la vinblastine et de ses derives |
| EP86870042A EP0222722B1 (fr) | 1985-11-12 | 1986-04-08 | Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE89567T1 true ATE89567T1 (de) | 1993-06-15 |
Family
ID=26106792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86870042T ATE89567T1 (de) | 1985-11-12 | 1986-04-08 | Konjugate von vinblastin und seine derivate, verfahren zur herstellung derselben und diese konjugate enthaltende pharmazeutische zusammensetzungen. |
Country Status (6)
| Country | Link |
|---|---|
| AT (1) | ATE89567T1 (fr) |
| AU (1) | AU577206B2 (fr) |
| DK (1) | DK164107C (fr) |
| GR (1) | GR862436B (fr) |
| HU (1) | HU196217B (fr) |
| OA (1) | OA08424A (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2508905B1 (fr) * | 1981-07-01 | 1984-01-27 | Roussel Uclaf | |
| EP0178683B1 (fr) * | 1984-10-19 | 1989-08-09 | Nihon Medi-Physics Co., Ltd. | Essai immunologique pour estriol-3-sulfate |
| IL82579A0 (en) * | 1986-05-27 | 1987-11-30 | Lilly Co Eli | Immunoglobulin conjugates |
| US5094849A (en) * | 1988-08-08 | 1992-03-10 | Eli Lilly And Company | Cytotoxic antibody conjugates of hydrazide derivatized vinca analogs via simple organic linkers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR81790B (fr) * | 1983-04-29 | 1984-12-12 | Omnichem Sa |
-
1986
- 1986-04-08 AT AT86870042T patent/ATE89567T1/de not_active IP Right Cessation
- 1986-09-24 GR GR862436A patent/GR862436B/el unknown
- 1986-09-30 AU AU63401/86A patent/AU577206B2/en not_active Ceased
- 1986-10-03 DK DK473286A patent/DK164107C/da not_active IP Right Cessation
- 1986-10-06 HU HU864190A patent/HU196217B/hu not_active IP Right Cessation
- 1986-10-07 OA OA58971A patent/OA08424A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU196217B (en) | 1988-10-28 |
| AU577206B2 (en) | 1988-09-15 |
| DK473286D0 (da) | 1986-10-03 |
| GR862436B (en) | 1986-12-23 |
| AU6340186A (en) | 1988-04-14 |
| OA08424A (fr) | 1988-06-30 |
| HUT42493A (en) | 1987-07-28 |
| DK473286A (da) | 1987-05-13 |
| DK164107B (da) | 1992-05-11 |
| DK164107C (da) | 1992-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |