ATE90393T1 - Differentialbindung von potentialsempfindlichen materialien durch lymphocyten. - Google Patents
Differentialbindung von potentialsempfindlichen materialien durch lymphocyten.Info
- Publication number
- ATE90393T1 ATE90393T1 AT88900054T AT88900054T ATE90393T1 AT E90393 T1 ATE90393 T1 AT E90393T1 AT 88900054 T AT88900054 T AT 88900054T AT 88900054 T AT88900054 T AT 88900054T AT E90393 T1 ATE90393 T1 AT E90393T1
- Authority
- AT
- Austria
- Prior art keywords
- lymphocytes
- pulses
- fluorescence intensity
- mps
- intensity
- Prior art date
Links
- 210000004698 lymphocyte Anatomy 0.000 title abstract 6
- 239000000463 material Substances 0.000 title abstract 3
- 239000000975 dye Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 230000036210 malignancy Effects 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 230000002902 bimodal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 239000007850 fluorescent dye Substances 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Virology (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Measurement Of Radiation (AREA)
- Radar Systems Or Details Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/933,982 US4835103A (en) | 1986-11-24 | 1986-11-24 | Differential binding of membrane potential sensitive materials to lymphocytes |
| PCT/US1987/003054 WO1988003955A1 (en) | 1986-11-24 | 1987-11-20 | Differential binding of potential sensitive materials by lymphocytes |
| EP88900054A EP0339028B1 (de) | 1986-11-24 | 1987-11-20 | Differentialbindung von potentialsempfindlichen materialien durch lymphocyten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE90393T1 true ATE90393T1 (de) | 1993-06-15 |
Family
ID=25464748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88900054T ATE90393T1 (de) | 1986-11-24 | 1987-11-20 | Differentialbindung von potentialsempfindlichen materialien durch lymphocyten. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4835103A (de) |
| EP (1) | EP0339028B1 (de) |
| JP (1) | JPH02501975A (de) |
| AT (1) | ATE90393T1 (de) |
| AU (1) | AU611877B2 (de) |
| CA (1) | CA1312537C (de) |
| DE (1) | DE3786175T2 (de) |
| DK (1) | DK169565B1 (de) |
| FI (1) | FI92076C (de) |
| NO (1) | NO173409C (de) |
| WO (1) | WO1988003955A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260186A (en) * | 1986-03-10 | 1993-11-09 | Boris Cercek | Provision of density specific blood cells for the structuredness of the cytoplasmic matrix (SCM) test |
| JP2549665B2 (ja) * | 1987-07-31 | 1996-10-30 | 東亜医用電子株式会社 | フロ−サイトメトリ用網状赤血球測定試薬 |
| JPH03503763A (ja) * | 1988-03-11 | 1991-08-22 | サーセク・ボリス | 一般的な癌‐関連scm‐認識因子、調製品及び使用方法 |
| JPH03122553A (ja) * | 1989-10-04 | 1991-05-24 | Olympus Optical Co Ltd | 光センサー |
| US5355215A (en) * | 1992-09-30 | 1994-10-11 | Environmental Research Institute Of Michigan | Method and apparatus for quantitative fluorescence measurements |
| US6800452B1 (en) | 1994-08-08 | 2004-10-05 | Science Applications International Corporation | Automated methods for simultaneously performing a plurality of signal-based assays |
| US6944493B2 (en) * | 1999-09-10 | 2005-09-13 | Akora, Inc. | Indocyanine green (ICG) compositions and related methods of use |
| US6351663B1 (en) | 1999-09-10 | 2002-02-26 | Akorn, Inc. | Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation |
| US6443976B1 (en) | 1999-11-30 | 2002-09-03 | Akorn, Inc. | Methods for treating conditions and illnesses associated with abnormal vasculature |
| US7994485B2 (en) * | 2008-04-08 | 2011-08-09 | Carestream Health, Inc. | Apparatus and method for fluorescence measurements using spatially structured illumination |
| US20150182518A1 (en) | 2012-10-26 | 2015-07-02 | Canon Kabushiki Kaisha | Cancer cell inhibitory drug and cancer stem-cell detection probe |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4173136A (en) * | 1977-11-17 | 1979-11-06 | Schroth Wilhelm Heinrich | Method and apparatus for producing multiple groove V-belt pulleys |
| DE2962866D1 (en) * | 1978-03-09 | 1982-07-08 | Merck Patent Gmbh | Method for determining leukaemic cells |
| US4343782A (en) * | 1978-04-20 | 1982-08-10 | Shapiro Howard M | Cytological assay procedure |
| US4424201A (en) * | 1978-11-28 | 1984-01-03 | Rockefeller University | Employment of a mereyanine dye for the detection of malignant leukocytic cells |
| US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
-
1986
- 1986-11-24 US US06/933,982 patent/US4835103A/en not_active Expired - Fee Related
-
1987
- 1987-11-20 JP JP63500465A patent/JPH02501975A/ja active Pending
- 1987-11-20 EP EP88900054A patent/EP0339028B1/de not_active Expired - Lifetime
- 1987-11-20 DE DE8888900054T patent/DE3786175T2/de not_active Expired - Fee Related
- 1987-11-20 WO PCT/US1987/003054 patent/WO1988003955A1/en not_active Ceased
- 1987-11-20 AT AT88900054T patent/ATE90393T1/de not_active IP Right Cessation
- 1987-11-20 AU AU10413/88A patent/AU611877B2/en not_active Ceased
- 1987-11-23 CA CA000552502A patent/CA1312537C/en not_active Expired - Fee Related
-
1988
- 1988-07-22 NO NO883260A patent/NO173409C/no unknown
- 1988-07-22 FI FI883489A patent/FI92076C/fi not_active IP Right Cessation
- 1988-07-22 DK DK413688A patent/DK169565B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3786175D1 (de) | 1993-07-15 |
| FI92076C (fi) | 1994-09-26 |
| FI883489A0 (fi) | 1988-07-22 |
| WO1988003955A1 (en) | 1988-06-02 |
| DK169565B1 (da) | 1994-11-28 |
| AU1041388A (en) | 1988-06-16 |
| FI92076B (fi) | 1994-06-15 |
| AU611877B2 (en) | 1991-06-27 |
| JPH02501975A (ja) | 1990-07-05 |
| DK413688D0 (da) | 1988-07-22 |
| FI883489L (fi) | 1988-07-22 |
| NO883260L (no) | 1988-09-23 |
| EP0339028A1 (de) | 1989-11-02 |
| DE3786175T2 (de) | 1993-09-23 |
| NO883260D0 (no) | 1988-07-22 |
| DK413688A (da) | 1988-09-21 |
| US4835103A (en) | 1989-05-30 |
| CA1312537C (en) | 1993-01-12 |
| NO173409B (no) | 1993-08-30 |
| NO173409C (no) | 1993-12-08 |
| EP0339028B1 (de) | 1993-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |