ATE90792T1 - Diagnostische verfahren zum nachweis von lymphomen bei menschen. - Google Patents
Diagnostische verfahren zum nachweis von lymphomen bei menschen.Info
- Publication number
- ATE90792T1 ATE90792T1 AT87305863T AT87305863T ATE90792T1 AT E90792 T1 ATE90792 T1 AT E90792T1 AT 87305863 T AT87305863 T AT 87305863T AT 87305863 T AT87305863 T AT 87305863T AT E90792 T1 ATE90792 T1 AT E90792T1
- Authority
- AT
- Austria
- Prior art keywords
- translocation
- humans
- detecting
- diagnostic methods
- gene
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57575—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/883,687 US5015568A (en) | 1986-07-09 | 1986-07-09 | Diagnostic methods for detecting lymphomas in humans |
| EP87305863A EP0252685B1 (de) | 1986-07-09 | 1987-07-02 | Diagnostische Verfahren zum Nachweis von Lymphomen bei Menschen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE90792T1 true ATE90792T1 (de) | 1993-07-15 |
Family
ID=25383120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87305863T ATE90792T1 (de) | 1986-07-09 | 1987-07-02 | Diagnostische verfahren zum nachweis von lymphomen bei menschen. |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US5015568A (de) |
| EP (1) | EP0252685B1 (de) |
| JP (1) | JPS63100379A (de) |
| AT (1) | ATE90792T1 (de) |
| AU (1) | AU602704B2 (de) |
| CA (1) | CA1340827C (de) |
| DE (2) | DE252685T1 (de) |
| ES (1) | ES2003064T3 (de) |
| GR (1) | GR880300131T1 (de) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| US5831066A (en) | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| US6841541B1 (en) | 1992-02-21 | 2005-01-11 | The Trustees Of The University Of Pennsylvania | Regulation of BCL-2-gene expression |
| AU5932790A (en) * | 1989-07-03 | 1991-01-17 | Temple University | Tcl-5 gene rearrangement involved in t-cell leukemia and melanoma |
| WO1991009974A1 (en) * | 1989-12-27 | 1991-07-11 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Diagnostic probe for detecting human stomach cancer |
| EP0515573A1 (de) * | 1990-02-23 | 1992-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Transkriptionsfaktoren mit einer pathogenen rolle in humanen neoplasias |
| IT1255770B (it) * | 1992-05-22 | 1995-11-15 | Consiglio Nazionale Ricerche | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi |
| US6902732B2 (en) | 1992-06-12 | 2005-06-07 | Massachusetts Institute Of Technology | Identification and characterization of a gene which protects cells from programmed cell death and uses therefor |
| WO1993025683A1 (en) * | 1992-06-12 | 1993-12-23 | Massachusetts Institute Of Technology | A gene which prevents programmed cell death |
| US5501952A (en) * | 1992-07-17 | 1996-03-26 | Aprogenex, Inc. | Analogues of reporter groups as background reducers in hybridization assays |
| US5641672A (en) * | 1993-06-09 | 1997-06-24 | The Trustees Of Columbia University In The City Of New York | Cloning and uses of the genetic locus bcl-6 |
| US5646008A (en) * | 1993-06-22 | 1997-07-08 | The Regent Of The University Of Michigan | Vertebrate apoptosis gene: compositions and methods |
| US5622852A (en) * | 1994-10-31 | 1997-04-22 | Washington University | Bcl-x/Bcl-2 associated cell death regulator |
| US5529925A (en) | 1993-12-03 | 1996-06-25 | St. Jude Children's Research Hospital | Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma |
| US6696548B2 (en) | 1993-12-03 | 2004-02-24 | St. Jude Children's Research Hospital | Antibodies for recognition of alk protein tyrosine/kinase receptor |
| US5672686A (en) * | 1994-08-09 | 1997-09-30 | Immunogen, Inc. | Bcl-Y - specific antibodies |
| US5985598A (en) * | 1994-10-27 | 1999-11-16 | Thomas Jefferson University | TCL-1 gene and protein and related methods and compositions |
| US7175995B1 (en) | 1994-10-27 | 2007-02-13 | Thomas Jefferson University | TCL-1 protein and related methods |
| US5789389A (en) * | 1995-03-17 | 1998-08-04 | Board Of Trustees Of University Of Illinois | BCL2 derived genetic elements associated with sensitivity to chemotherapeutic drugs |
| US5695944A (en) * | 1995-05-05 | 1997-12-09 | Thomas Jefferson University | Modulation of bcl-2 phosphorylation |
| US5656725A (en) * | 1995-05-12 | 1997-08-12 | Apoptosis Technology, Inc. | Peptides and compositions which modulate apoptosis |
| US6221615B1 (en) * | 1995-05-12 | 2001-04-24 | Apoptosis Technology, Inc. | Peptides and compositions which modulate apoptosis |
| US5789201A (en) * | 1996-02-23 | 1998-08-04 | Cocensys, Inc. | Genes coding for bcl-y a bcl-2 homologue |
| AUPN896596A0 (en) | 1996-03-27 | 1996-04-26 | Walter And Eliza Hall Institute Of Medical Research, The | Therapeutic molecules |
| AU728863B2 (en) * | 1996-03-27 | 2001-01-18 | Walter And Eliza Hall Institute Of Medical Research, The | A novel mammalian gene, bcl-w, belongs to the bcl-2 family of apoptosis-controlling genes |
| US5821082A (en) | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
| US6977244B2 (en) | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
| US5837838A (en) | 1997-03-14 | 1998-11-17 | The Burnham Institute | Bax inhibitor proteins |
| US6337184B1 (en) | 1997-04-01 | 2002-01-08 | Jeffrey B. Miller | Molecular marker for muscle stem cells |
| EP0878552A1 (de) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molekularer Nachweis von chromosomalen Veränderungen |
| US6849400B1 (en) | 1997-07-23 | 2005-02-01 | Gen-Probe Incorporated | Methods for detecting and measuring spliced nucleic acids |
| US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
| US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
| US20010041342A1 (en) * | 1998-04-01 | 2001-11-15 | The General Hospital Corporation, A Massachusetts Corporation | Molecular marker for muscle stem cells |
| WO1999057309A1 (en) * | 1998-05-04 | 1999-11-11 | Dako A/S | Method and probes for the detection of chromosome aberrations |
| ATE291737T1 (de) * | 2000-01-14 | 2005-04-15 | Migenix Corp | Screening-assays unter verwendung von intramitochondrialem kalzium |
| WO2001052639A1 (en) * | 2000-01-21 | 2001-07-26 | Beth Israel Deaconess Medical Center | Use of pro-apoptotic factors in treatment of atherosclerosis |
| US7795232B1 (en) * | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| US20030044803A1 (en) * | 2000-09-22 | 2003-03-06 | Pedersen Finn Skou | Methods for diagnosis and treatment of diseases associated with altered expression of JAK1 |
| US20030077590A1 (en) * | 2000-09-22 | 2003-04-24 | Pedersen Finn Skou | Methods for diagnosis and treatment of diseases associated with altered expression of neurogranin |
| US20040147473A1 (en) * | 2000-11-10 | 2004-07-29 | Warrell Raymond P. | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| US20070098728A1 (en) * | 2001-09-24 | 2007-05-03 | Pedersen Finn S | Novel compositions and methods in cancer |
| DK3115470T3 (en) * | 2002-03-13 | 2018-11-05 | Genomic Health Inc | Gene Expression Profiling in Tumor Tissue Biopsies |
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| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
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| DK1641810T4 (en) | 2003-06-24 | 2017-07-03 | Genomic Health Inc | Predicting the likelihood of cancer recurrence |
| ES2905579T3 (es) * | 2003-07-10 | 2022-04-11 | Genomic Health Inc | Algoritmo del perfil de expresión y prueba para el pronóstico de la recaída del cáncer de mama |
| EP1699936B1 (de) | 2003-12-23 | 2011-02-09 | Genomic Health, Inc. | Universelle vervielfältigung von fragmentierter rns |
| EP1737980A2 (de) | 2004-04-09 | 2007-01-03 | Fondazione IRCCS Istituto Nazionale dei Tumori | Genexpressionsmarker zur vorhersage des ansprechens auf chemotherapie |
| EP1789581A4 (de) * | 2004-07-12 | 2008-06-11 | Sbarro Health Res Organization | Verfahren zur bestimmung des vorliegens von krebs durch analyse der expression von cdk9 und/oder cyclin t1 in lymphoidgewebe |
| EP2527837A1 (de) * | 2004-10-04 | 2012-11-28 | University of Washington | Verfahren zur Verhinderung von Zelltod oder -entzündung bei Säugetieren |
| WO2006052731A2 (en) | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| CA2585571C (en) * | 2004-11-05 | 2020-01-21 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| CN101341259B (zh) * | 2005-08-01 | 2011-12-21 | 俄亥俄州立大学研究基金会 | 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物 |
| EP1937280B1 (de) * | 2005-09-12 | 2014-08-27 | The Ohio State University Research Foundation | Zusammensetzungen zur Therapie von Bcl2-assoziierten Tumoren |
| CA2624531A1 (en) * | 2005-10-05 | 2007-04-19 | Carlo M. Croce | Wwox gene, vectors containing the same, and uses in treatment of cancer |
| ES2429404T3 (es) | 2006-01-05 | 2013-11-14 | The Ohio State University Research Foundation | Procedimientos basados en los microARN para el diagnóstico y el pronóstico del cáncer de pulmón |
| EP2487261B1 (de) | 2006-01-05 | 2015-07-01 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von festen Krebsen |
| JP5490413B2 (ja) | 2006-01-05 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常 |
| CN101384903A (zh) | 2006-02-09 | 2009-03-11 | 南佛罗里达大学 | 利用bcl-2水平的增高检测癌肿 |
| CA2646051A1 (en) | 2006-03-20 | 2007-09-27 | Carlo M. Croce | Microrna fingerprints during human megakaryocytopoiesis |
| WO2008008430A2 (en) * | 2006-07-13 | 2008-01-17 | The Ohio State University Research Foundation | Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases |
| US8071292B2 (en) * | 2006-09-19 | 2011-12-06 | The Ohio State University Research Foundation | Leukemia diagnostic methods |
| EP2087135B8 (de) | 2006-11-01 | 2013-07-24 | The Ohio State University Research Foundation | Mikro-rna-expressionssignatur zur vorhersage des überlebens und von metastasen bei hepatozellulärem karzinom |
| CN103555825B (zh) * | 2007-01-31 | 2015-09-30 | 俄亥俄州立大学研究基金会 | 用于急性髓细胞白血病(aml)的诊断、预后和治疗的基于微rna的方法和组合物 |
| WO2008136971A1 (en) * | 2007-04-30 | 2008-11-13 | The Ohio State University Research Foundation | Methods for differentiating pancreatic cancer from normal pancreatic function and/or chronic pancreatitis |
| ES2527648T3 (es) * | 2007-06-08 | 2015-01-28 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Métodos para determinar el subtipo de carcinoma hepatocelular |
| US8053186B2 (en) * | 2007-06-15 | 2011-11-08 | The Ohio State University Research Foundation | Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing |
| CA2695184A1 (en) * | 2007-07-31 | 2009-02-05 | The Ohio State University Research Foundation | Methods for reverting methylation by targeting dnmt3a and dnmt3b |
| ES2570359T3 (es) * | 2007-08-03 | 2016-05-18 | Univ Ohio State Res Found | Regiones ultraconservadas que codifican ARNnc |
| EP3028708A1 (de) * | 2007-08-22 | 2016-06-08 | The Ohio State University Research Foundation | Verfahren und zusammensetzungen zur induzierung von epha7-deregulierung und erk-phosphorlylierung bei humaner akuter leukämie |
| AU2008296022B2 (en) * | 2007-09-06 | 2014-01-23 | The Ohio State University Research Foundation | MicroRNA signatures in human ovarian cancer |
| CA2702241A1 (en) * | 2007-10-11 | 2009-04-16 | The Ohio State University Research Foundation | Methods and compositions for the diagnosis and treatment of esophageal adenocarcinomas |
| JP2011504093A (ja) | 2007-10-26 | 2011-02-03 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 脆弱性ヒスチジン三連構造(fhit)相互作用を同定するための方法およびその使用 |
| US20100323357A1 (en) * | 2007-11-30 | 2010-12-23 | The Ohio State University Research Foundation | MicroRNA Expression Profiling and Targeting in Peripheral Blood in Lung Cancer |
| EP2260109A4 (de) * | 2008-02-28 | 2011-06-08 | Univ Ohio State Res Found | Verfahren und zusammensetzungen auf microrna-basis zur diagnose, prognose und behandlung von erkrankungen in verbindung mit der prostata |
| EP2254668A4 (de) * | 2008-02-28 | 2012-08-15 | Univ Ohio State Res Found | Mit menschlicher chronisch lymphozytischer leukämie (cll) assoziierte microrna-signaturen und ihre verwendung |
| CN102149827B (zh) | 2008-06-11 | 2014-08-20 | 由卫生与公众服务部代表的美利坚合众国政府 | MiR-26家族作为肝细胞癌和对治疗的应答性的预测性标志物的用途 |
| US9569912B2 (en) | 2008-06-26 | 2017-02-14 | Shopatm Bv (Sarl) | Article storage and retrieval apparatus and vending machine |
| JP5960060B2 (ja) | 2009-11-23 | 2016-08-02 | ジ・オハイオ・ステート・ユニバーシティ | 腫瘍細胞の増殖、遊走および浸潤に影響を与えるために有用な物質および方法 |
| CA2816603A1 (en) | 2010-11-12 | 2012-05-18 | The Ohio State University Research Foundation | Materials and methods related to microrna-21, mismatch repair, and colorectal cancer |
| EP2640368B1 (de) | 2010-11-15 | 2020-12-30 | The Ohio State University Research Foundation | Mukoadhäsive systeme mit kontrollierter freisetzung |
| EP2683387A4 (de) | 2011-03-07 | 2014-09-03 | Univ Ohio State | Durch mikro-rna-155 (mir-155) induzierte mutatorgenaktivität gegen entzündungen und krebs |
| CN104364390B (zh) | 2011-10-14 | 2016-08-24 | 俄亥俄州立大学 | 与卵巢癌相关的方法和材料 |
| EP2790735A4 (de) | 2011-12-13 | 2015-12-09 | Ohio State Innovation Foundation | Verfahren und zusammensetzungen im zusammenhang mit mir-21 und mir-29a, exosomerhemmung und krebsmetastasen |
| CN104685065B (zh) | 2012-01-20 | 2017-02-22 | 俄亥俄州立大学 | 浸润性和预后的乳腺癌生物标志物标签 |
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| US4513088A (en) * | 1983-03-30 | 1985-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Assay for monoclonal antibody against surface Ig of a human B cell tumor |
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| US4701409A (en) * | 1984-11-15 | 1987-10-20 | The Wistar Institute | Detection of B-cell neoplasms |
| US4692405A (en) * | 1985-03-05 | 1987-09-08 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies to antigen on activated human B-cells and assay therefor, protein antigenic determinant therefor and method of making same |
| IL79755A0 (en) * | 1985-08-21 | 1986-11-30 | Oncogene Science Inc | Immunoassay for detection of ras encoded protein |
| US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| IT1244983B (it) * | 1991-04-29 | 1994-09-13 | Raggio Italgene Spa | Procedimento per rivelare sequenze di acidi nucleici e kit per la sua utilizzazione. |
-
1986
- 1986-07-09 US US06/883,687 patent/US5015568A/en not_active Expired - Lifetime
-
1987
- 1987-07-02 ES ES87305863T patent/ES2003064T3/es not_active Expired - Lifetime
- 1987-07-02 DE DE198787305863T patent/DE252685T1/de active Pending
- 1987-07-02 DE DE87305863T patent/DE3786200T2/de not_active Expired - Lifetime
- 1987-07-02 AT AT87305863T patent/ATE90792T1/de not_active IP Right Cessation
- 1987-07-02 EP EP87305863A patent/EP0252685B1/de not_active Expired - Lifetime
- 1987-07-08 AU AU75328/87A patent/AU602704B2/en not_active Expired
- 1987-07-08 CA CA000541606A patent/CA1340827C/en not_active Expired - Lifetime
- 1987-07-09 JP JP62172023A patent/JPS63100379A/ja active Pending
-
1988
- 1988-12-16 GR GR88300131T patent/GR880300131T1/el unknown
-
1992
- 1992-12-23 US US07/994,941 patent/US5595869A/en not_active Expired - Lifetime
-
1994
- 1994-04-18 US US08/228,704 patent/US5459251A/en not_active Expired - Lifetime
-
1995
- 1995-05-05 US US08/435,181 patent/US5523393A/en not_active Expired - Lifetime
- 1995-05-05 US US08/435,193 patent/US5506344A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5595869A (en) | 1997-01-21 |
| DE252685T1 (de) | 1988-06-30 |
| ES2003064T3 (es) | 1994-09-01 |
| EP0252685A3 (en) | 1990-07-11 |
| US5015568A (en) | 1991-05-14 |
| US5459251A (en) | 1995-10-17 |
| AU7532887A (en) | 1988-02-18 |
| US5523393A (en) | 1996-06-04 |
| DE3786200D1 (de) | 1993-07-22 |
| EP0252685A2 (de) | 1988-01-13 |
| JPS63100379A (ja) | 1988-05-02 |
| US5506344A (en) | 1996-04-09 |
| EP0252685B1 (de) | 1993-06-16 |
| CA1340827C (en) | 1999-11-23 |
| DE3786200T2 (de) | 1993-10-07 |
| ES2003064A4 (es) | 1988-10-16 |
| AU602704B2 (en) | 1990-10-25 |
| GR880300131T1 (en) | 1988-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |