ATE94164T1 - Benzimidazol-derivate und verfahren zu deren herstellung. - Google Patents

Benzimidazol-derivate und verfahren zu deren herstellung.

Info

Publication number
ATE94164T1
ATE94164T1 AT88401866T AT88401866T ATE94164T1 AT E94164 T1 ATE94164 T1 AT E94164T1 AT 88401866 T AT88401866 T AT 88401866T AT 88401866 T AT88401866 T AT 88401866T AT E94164 T1 ATE94164 T1 AT E94164T1
Authority
AT
Austria
Prior art keywords
hydrogen
methyl
manufacture
benzimidazole derivatives
acetyl
Prior art date
Application number
AT88401866T
Other languages
English (en)
Inventor
Philippe Manoury
Guy Rossey
Jean Binet
Gerard Defosse
Najib Jabri
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of ATE94164T1 publication Critical patent/ATE94164T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Liquid Developers In Electrophotography (AREA)
AT88401866T 1987-07-23 1988-07-20 Benzimidazol-derivate und verfahren zu deren herstellung. ATE94164T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8710409A FR2618435B1 (fr) 1987-07-23 1987-07-23 Derives de benzimidazole, leur preparation et leur application en therapeutique
EP88401866A EP0304353B1 (de) 1987-07-23 1988-07-20 Benzimidazol-Derivate und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ATE94164T1 true ATE94164T1 (de) 1993-09-15

Family

ID=9353449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88401866T ATE94164T1 (de) 1987-07-23 1988-07-20 Benzimidazol-derivate und verfahren zu deren herstellung.

Country Status (19)

Country Link
US (1) US4857536A (de)
EP (1) EP0304353B1 (de)
JP (1) JP2690749B2 (de)
KR (1) KR890002111A (de)
AT (1) ATE94164T1 (de)
AU (1) AU602418B2 (de)
CA (1) CA1310010C (de)
DE (1) DE3883891T2 (de)
DK (1) DK413188A (de)
ES (1) ES2059550T3 (de)
FI (1) FI883484A7 (de)
FR (1) FR2618435B1 (de)
HU (1) HUT47266A (de)
IE (1) IE61824B1 (de)
IL (1) IL87174A (de)
NO (1) NO883263L (de)
NZ (1) NZ225528A (de)
PT (1) PT88089B (de)
ZA (1) ZA885367B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658823B1 (fr) * 1990-02-27 1992-04-30 Adir Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .
FI932687A7 (fi) * 1990-12-14 1993-06-11 Merrell Dow Pharma Allergianvastaisia yhdisteitä
FR2674853B1 (fr) * 1991-04-03 1995-01-20 Synthelabo Derives de piperidinylguanidine, leur preparation et leur application en therapeutique.
US5223704A (en) * 1992-03-31 1993-06-29 At&T Bell Laboratories Planar buried quantum well photodetector
FR2693194B1 (fr) * 1992-07-03 1994-09-23 Synthelabo Dérivés d'alcanecarboxamide, leur préparation et leur application thérapeutique.
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
CA3079081A1 (en) 2017-10-19 2019-04-25 Michael D. Bartberger Benzimidazole derivatives and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3528991A (en) * 1964-02-19 1970-09-15 Sterling Drug Inc 1h- and 2h-benzotriazolyl-lower-alkyl-amidoximes,-amidines,and -guanidines
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
US4347856A (en) * 1980-05-20 1982-09-07 United States Tobacco Company Method and apparatus for removing cigar wrappers from the web of a bobbin
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
FR2587029B1 (fr) * 1985-09-11 1987-10-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES2059550T3 (es) 1994-11-16
IE61824B1 (en) 1994-11-30
EP0304353B1 (de) 1993-09-08
IE882257L (en) 1989-01-23
FI883484L (fi) 1989-01-24
NO883263D0 (no) 1988-07-22
FR2618435B1 (fr) 1989-10-27
AU1971688A (en) 1989-01-27
CA1310010C (en) 1992-11-10
AU602418B2 (en) 1990-10-11
FR2618435A1 (fr) 1989-01-27
DK413188A (da) 1989-01-24
DE3883891T2 (de) 1994-04-14
US4857536A (en) 1989-08-15
ZA885367B (en) 1989-06-28
KR890002111A (ko) 1989-04-08
JPS6434978A (en) 1989-02-06
JP2690749B2 (ja) 1997-12-17
PT88089A (pt) 1989-06-30
HUT47266A (en) 1989-02-28
PT88089B (pt) 1995-03-01
NZ225528A (en) 1990-05-28
FI883484A7 (fi) 1989-01-24
FI883484A0 (fi) 1988-07-22
IL87174A (en) 1993-02-21
DE3883891D1 (de) 1993-10-14
DK413188D0 (da) 1988-07-22
NO883263L (no) 1989-01-24
EP0304353A1 (de) 1989-02-22
IL87174A0 (en) 1988-12-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee