ATE98230T1 - Indolderivate. - Google Patents

Indolderivate.

Info

Publication number
ATE98230T1
ATE98230T1 AT90301419T AT90301419T ATE98230T1 AT E98230 T1 ATE98230 T1 AT E98230T1 AT 90301419 T AT90301419 T AT 90301419T AT 90301419 T AT90301419 T AT 90301419T AT E98230 T1 ATE98230 T1 AT E98230T1
Authority
AT
Austria
Prior art keywords
compounds
disclosed
group
headache
migraine
Prior art date
Application number
AT90301419T
Other languages
English (en)
Inventor
Peter Charles North
Martin Johnson
Alexander William Oxford
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE98230T1 publication Critical patent/ATE98230T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90301419T 1989-02-10 1990-02-09 Indolderivate. ATE98230T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898903036A GB8903036D0 (en) 1989-02-10 1989-02-10 Chemical compounds
EP90301419A EP0382570B1 (de) 1989-02-10 1990-02-09 Indolderivate

Publications (1)

Publication Number Publication Date
ATE98230T1 true ATE98230T1 (de) 1993-12-15

Family

ID=10651482

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90301419T ATE98230T1 (de) 1989-02-10 1990-02-09 Indolderivate.

Country Status (16)

Country Link
US (1) US5001135A (de)
EP (1) EP0382570B1 (de)
JP (1) JP2941333B2 (de)
KR (1) KR900012925A (de)
CN (1) CN1058778A (de)
AT (1) ATE98230T1 (de)
AU (1) AU4931590A (de)
CA (1) CA2009745A1 (de)
DE (1) DE69004989T2 (de)
FI (1) FI900641A7 (de)
GB (1) GB8903036D0 (de)
IL (1) IL93337A0 (de)
NO (1) NO900636L (de)
NZ (1) NZ232449A (de)
PT (1) PT93112A (de)
ZA (1) ZA90974B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH24976A (en) * 1987-08-13 1990-12-26 Glaxo Group Ltd Indole derivatives
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
FR2701026B1 (fr) * 1993-02-02 1995-03-31 Adir Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
GB9320115D0 (en) * 1993-09-29 1993-11-17 Glaxo Group Ltd Process
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
KR19980703048A (ko) * 1995-03-20 1998-09-05 피터쥐.스트링거 5-치환-3-(1,2,3,6-테트라히드로피리딘-4-일)- 및 3-(피페리딘-4-일)-1ｈ-인돌: 신규한 5-ｈｔ1ｆ 아고니스트
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2183235A (en) * 1935-03-08 1939-12-12 Ici Ltd Automatic control of variable physical characteristics
US3409626A (en) * 1963-09-17 1968-11-05 Neisler Lab Inc Indolylethyl pyridinium quaternary ammonium compounds
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
US3217811A (en) * 1964-12-16 1965-11-16 United Aircraft Corp Rotor head fairing for high speed vehicle
GB1410783A (en) * 1972-01-20 1975-10-22 Wyeth John & Brother Ltd N-substituted 4-amidopyridines tetrahydropyridines and piperidines
GR79215B (de) * 1982-06-07 1984-10-22 Glaxo Group Ltd
US4785016A (en) * 1984-12-04 1988-11-15 Glaxo Group Limited Indole derivatives
DE3518300A1 (de) * 1985-05-22 1986-11-27 Horst E. 7240 Horb Dreier Schaltgeraet fuer rechnergesteuerte werkzeugmaschinen und messanordnung unter dessen verwendung
GB8601959D0 (en) * 1986-01-28 1986-03-05 Glaxo Group Ltd Indole derivatives
PH24976A (en) * 1987-08-13 1990-12-26 Glaxo Group Ltd Indole derivatives

Also Published As

Publication number Publication date
KR900012925A (ko) 1990-09-03
IL93337A0 (en) 1990-11-29
FI900641A7 (fi) 1990-08-11
CA2009745A1 (en) 1990-08-10
ZA90974B (en) 1991-10-30
AU4931590A (en) 1990-08-16
NO900636D0 (no) 1990-02-09
NZ232449A (en) 1991-07-26
NO900636L (no) 1990-08-13
DE69004989T2 (de) 1994-03-24
GB8903036D0 (en) 1989-03-30
JP2941333B2 (ja) 1999-08-25
JPH02300184A (ja) 1990-12-12
EP0382570B1 (de) 1993-12-08
EP0382570A1 (de) 1990-08-16
DE69004989D1 (de) 1994-01-20
US5001135A (en) 1991-03-19
CN1058778A (zh) 1992-02-19
PT93112A (pt) 1990-08-31
FI900641A0 (fi) 1990-02-09

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties