AU1331702A - Improved process for water soluble azole compounds - Google Patents

Improved process for water soluble azole compounds

Info

Publication number: AU1331702A
Authority: AU; Australia
Prior art keywords: improved process; water soluble; azole compounds; soluble azole; triazole antifungal
Prior art date: 2000-11-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

AU1331702A

Other languages

English (en)

Inventor

Chung-Pin Chen

Timothy Paul Connolly

Laxima Reddy Kolla

John D Matiskella

Richard H Mueller

Yadagiri Rendri

Dejah T Petsch

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-20

Filing date

2001-10-18

Publication date

2002-06-03

2001-10-18 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2002-06-03 Publication of AU1331702A publication Critical patent/AU1331702A/xx

Status Pending legal-status Critical Current

Links

150000003851 azoles Chemical class 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
230000000843 anti-fungal effect Effects 0.000 abstract 3
229940121375 antifungal agent Drugs 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
150000003852 triazoles Chemical class 0.000 abstract 3
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6518—Five-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preventing Corrosion Or Incrustation Of Metals (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AU1331702A 2000-11-20 2001-10-18 Improved process for water soluble azole compounds Pending AU1331702A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US25200100P	2000-11-20	2000-11-20
PCT/US2001/032382 WO2002042283A1 (en)	2000-11-20	2001-10-18	Improved process for water soluble azole compounds

Publications (1)

Publication Number	Publication Date
AU1331702A true AU1331702A (en)	2002-06-03

Family

ID=22954236

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU1331702A Pending AU1331702A (en)	2000-11-20	2001-10-18	Improved process for water soluble azole compounds
AU2002213317A Ceased AU2002213317B2 (en)	2000-11-20	2001-10-18	Improved process for water soluble azole compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2002213317A Ceased AU2002213317B2 (en)	2000-11-20	2001-10-18	Improved process for water soluble azole compounds

Country Status (18)

Country	Link
US (1)	US6448401B1 (cs)
EP (1)	EP1345915B1 (cs)
JP (1)	JP4579496B2 (cs)
KR (1)	KR100734456B1 (cs)
CN (1)	CN1279033C (cs)
AT (1)	ATE353079T1 (cs)
AU (2)	AU1331702A (cs)
BR (1)	BR0115448A (cs)
CA (1)	CA2429378C (cs)
CZ (1)	CZ20031388A3 (cs)
DE (1)	DE60126425T2 (cs)
ES (1)	ES2280405T3 (cs)
HU (1)	HUP0301917A3 (cs)
IL (2)	IL155612A0 (cs)
MX (1)	MXPA03004332A (cs)
NO (1)	NO20032241D0 (cs)
PL (1)	PL361003A1 (cs)
WO (1)	WO2002042283A1 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6362172B2 (en) *	2000-01-20	2002-03-26	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
TWI329105B (en)	2002-02-01	2010-08-21	Rigel Pharmaceuticals Inc	2,4-pyrimidinediamine compounds and their uses
ES2421139T3 (es) *	2003-07-30	2013-08-29	Rigel Pharmaceuticals, Inc.	Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias
US20060047135A1 (en) *	2004-08-30	2006-03-02	Chadwick Scott T	Process for preparing chloromethyl di-tert-butylphosphate
US7449458B2 (en)	2005-01-19	2008-11-11	Rigel Pharmaceuticals, Inc.	Prodrugs of 2,4-pyrimidinediamine compounds and their uses
JO2691B1 (en) *	2005-05-03	2013-03-03	ايساي آر آند دي مانجمنت كو.، ليمتد	Monolysine salts for azole compounds
CN101282979B (zh) *	2005-09-13	2011-09-21	卫材R&D管理有限公司	稳定性被改善的含有磷酸氯甲酯衍生物的组合物及其制备方法
EP1964843B1 (en) *	2005-12-20	2013-08-28	Eisai R&D Management Co., Ltd.	Process for production of water-soluble azole prodrug
KR101250632B1 (ko)	2006-02-22	2013-04-03	에자이 알앤드디 매니지먼트 가부시키가이샤	안정화 의약 조성물
CN101622263B (zh)	2007-03-06	2013-05-29	卫材R&D管理有限公司	稳定性被改善的含有磷酸氯甲酯衍生物的组合物及其制备方法
FI20070574A0 (fi) *	2007-07-30	2007-07-30	Kuopion Yliopisto	Vesiliukoinen propofolin etylideenifosfaatti-aihiolääke
EP2723452A2 (en)	2011-06-22	2014-04-30	Vyome Biosciences Pvt Ltd	Conjugate-based antifungal and antibacterial prodrugs
US11116722B2 (en) *	2016-10-14	2021-09-14	Pulmatrix Operating Company, Inc.	Antifungal dry powders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO310238B1 (no)	1992-12-24	2001-06-11	Bristol Myers Squibb Co	Kjemiske forbindelser og farmasöytisk preparat samt anvendelse av slike preparater
CA2129288C (en)	1993-08-17	2000-05-16	Jerzy Golik	Phosphonooxymethyl esters of taxane derivatives
DK0736030T3 (da)	1993-12-21	2001-10-29	Schering Corp	Fungicide tetrahydrofuraner
SG48386A1 (en) *	1994-01-24	1998-04-17	Janssen Pharmaceutica Nv	Watersoluble azole antifungals
NZ270418A (en) *	1994-02-07	1997-09-22	Eisai Co Ltd	Polycyclic triazole & imidazole derivatives, antifungal compositions
ES2199291T3 (es)	1995-06-02	2004-02-16	Schering Corporation	Antifungicos de tetrahidrofurano.
GB9602080D0 (en) *	1996-02-02	1996-04-03	Pfizer Ltd	Pharmaceutical compounds
EP0829478A3 (en)	1996-09-09	1998-03-25	F. Hoffmann-La Roche Ag	N-Benzylimidazolium and N-benzyltriazolium derivatives, their preparation and their use as antifungal and antimycotic agents
DK1056754T3 (da)	1998-01-29	2004-02-16	Bristol Myers Squibb Co	Phosphatderivater af diaryl-1,3,4-oxadiazolon
US5883097A (en)	1998-04-16	1999-03-16	Schering Corporation	Soluble azole antifungal salt
US6265584B1 (en)	1998-05-22	2001-07-24	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
US6204257B1 (en) *	1998-08-07	2001-03-20	Universtiy Of Kansas	Water soluble prodrugs of hindered alcohols
WO2000030655A1 (en) *	1998-11-20	2000-06-02	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
US6362172B2 (en) *	2000-01-20	2002-03-26	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds

2001
- 2001-10-16 US US09/982,199 patent/US6448401B1/en not_active Expired - Lifetime
- 2001-10-18 PL PL01361003A patent/PL361003A1/xx not_active Application Discontinuation
- 2001-10-18 ES ES01981688T patent/ES2280405T3/es not_active Expired - Lifetime
- 2001-10-18 WO PCT/US2001/032382 patent/WO2002042283A1/en not_active Ceased
- 2001-10-18 AU AU1331702A patent/AU1331702A/xx active Pending
- 2001-10-18 AU AU2002213317A patent/AU2002213317B2/en not_active Ceased
- 2001-10-18 DE DE60126425T patent/DE60126425T2/de not_active Expired - Lifetime
- 2001-10-18 CA CA002429378A patent/CA2429378C/en not_active Expired - Lifetime
- 2001-10-18 KR KR1020037006747A patent/KR100734456B1/ko not_active Expired - Fee Related
- 2001-10-18 EP EP01981688A patent/EP1345915B1/en not_active Expired - Lifetime
- 2001-10-18 CZ CZ20031388A patent/CZ20031388A3/cs unknown
- 2001-10-18 MX MXPA03004332A patent/MXPA03004332A/es unknown
- 2001-10-18 BR BR0115448-6A patent/BR0115448A/pt not_active IP Right Cessation
- 2001-10-18 IL IL15561201A patent/IL155612A0/xx unknown
- 2001-10-18 AT AT01981688T patent/ATE353079T1/de not_active IP Right Cessation
- 2001-10-18 HU HU0301917A patent/HUP0301917A3/hu unknown
- 2001-10-18 JP JP2002544418A patent/JP4579496B2/ja not_active Expired - Lifetime
- 2001-10-18 CN CNB018191665A patent/CN1279033C/zh not_active Expired - Fee Related
2003
- 2003-04-28 IL IL155612A patent/IL155612A/en not_active IP Right Cessation
- 2003-05-19 NO NO20032241A patent/NO20032241D0/no unknown

Also Published As

Publication number	Publication date
HUP0301917A3 (en)	2005-11-28
CN1279033C (zh)	2006-10-11
IL155612A (en)	2010-05-31
KR20040020865A (ko)	2004-03-09
JP4579496B2 (ja)	2010-11-10
EP1345915A1 (en)	2003-09-24
CA2429378C (en)	2008-03-18
EP1345915A4 (en)	2005-08-03
EP1345915B1 (en)	2007-01-31
KR100734456B1 (ko)	2007-07-03
CZ20031388A3 (cs)	2003-08-13
DE60126425T2 (de)	2007-10-18
CA2429378A1 (en)	2002-05-30
DE60126425D1 (de)	2007-03-22
IL155612A0 (en)	2003-11-23
JP2004518640A (ja)	2004-06-24
US20020062028A1 (en)	2002-05-23
WO2002042283A1 (en)	2002-05-30
AU2002213317B2 (en)	2007-03-15
ATE353079T1 (de)	2007-02-15
ES2280405T3 (es)	2007-09-16
CN1474817A (zh)	2004-02-11
BR0115448A (pt)	2004-02-17
PL361003A1 (en)	2004-09-20
HUP0301917A2 (hu)	2003-09-29
MXPA03004332A (es)	2004-05-04
US6448401B1 (en)	2002-09-10
NO20032241D0 (no)	2003-05-19

Publication	Publication Date	Title
IL150798A0 (en)	2003-02-12	Water soluble prodrugs of azole compounds
EP1345915A4 (en)	2005-08-03	IMPROVED METHOD FOR WATER SOLUBLE AZOL COMPOUNDS
WO2001066519A3 (es)	2002-01-31	Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica
ZA200102070B (en)	2002-09-13	Process for preparing resorcinol derivatives.
SG82073A1 (en)	2001-07-24	Improved shallow trench isolation process
AU2001277576A1 (en)	2002-01-21	Hydraulic turbine feed tank
WO2002016322A3 (en)	2002-06-06	Process for the preparation of 2-aminoethylpyridines
ZA200108623B (en)	2002-06-07	Process for preparing imidachloprid.
SI1325022T1 (sl)	2007-04-30	Metoda za pripravo 21-hidroksi-6,19-oksidoprogesterona (21oh-6op)
AU2001259516A1 (en)	2001-11-20	Preparation of secondary aminoisobutylalkoxysilanes
WO2000046210A3 (en)	2000-12-14	New process for preparing pesticidal intermediates
IN187760B (cs)	2002-06-15
AU2001286477A1 (en)	2002-02-25	Process for the preparation of water soluble polypyrrole
HU0203193D0 (cs)	2002-10-28
IL148161A0 (en)	2002-09-12	Process for the preparation of 2-cyanopyridines
AU1915500A (en)	2000-06-13	Water soluble prodrugs of azole compounds
WO2002051845A3 (en)	2002-10-10	Triazolopyrimidines
MY125989A (en)	2006-09-29	Water soluble prodrugs of azole compounds
AU2001280244A1 (en)	2002-03-13	Novel process for preparing 3-aminomethyl-4-z-methoxyiminopyrrolidine
HK1057554A (en)	2004-04-08	Improved process for water soluble azole compounds
ECSP993227A (es)	1999-12-23	Prodrogas hidrosolubles de compuesto azole
WO2002020490A3 (en)	2002-06-13	Process to produce halo-4-phenoxyquinolines
WO2002018364A3 (en)	2002-05-10	Process for preparing 2-phenyl-3-aminobenzothiophenes
AU2002214170A1 (en)	2002-05-06	Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds
AU2001261564A1 (en)	2001-11-26	Process for preparing cis-aminochromanols