AU2003235525B2 - New GDF-9 and GDF-9B (BMP-15) sequences for altering mammalian ovarian function and ovulation rate - Google Patents

New GDF-9 and GDF-9B (BMP-15) sequences for altering mammalian ovarian function and ovulation rate Download PDF

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Publication number
AU2003235525B2
AU2003235525B2 AU2003235525A AU2003235525A AU2003235525B2 AU 2003235525 B2 AU2003235525 B2 AU 2003235525B2 AU 2003235525 A AU2003235525 A AU 2003235525A AU 2003235525 A AU2003235525 A AU 2003235525A AU 2003235525 B2 AU2003235525 B2 AU 2003235525B2
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AU
Australia
Prior art keywords
gdf
nucleic acid
mutated
dna
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003235525A
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English (en)
Other versions
AU2003235525A1 (en
Inventor
George Henry Davis
Susan Mary Galloway
Scott Michael Gregan
James Patrick Hanrahan
Jennifer Lee Juengel
Kenneth Pattrick Mcnatty
Philippe Mulsant
Richard Patrick Powell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Ireland Galway NUI
New Zealand Institute for Bioeconomy Science Ltd
Original Assignee
National University of Ireland Galway NUI
AgResearch Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Ireland Galway NUI, AgResearch Ltd filed Critical National University of Ireland Galway NUI
Publication of AU2003235525A1 publication Critical patent/AU2003235525A1/en
Assigned to HANRAHAN, JAMES, OVITA LIMITED, MULSANT, PHILIPPE, NATIONAL UNIVERSITY OF IRELAND, GALWAY reassignment HANRAHAN, JAMES Request for Assignment Assignors: HANRAHAN, JAMES, MULSANT, PHILIPPE, OVITA LIMITED, POWELL, RICHARD
Assigned to AGRESEARCH LIMITED, HANRAHAN, JAMES, NATIONAL UNIVERSITY OF IRELAND, GALWAY, MULSANT, PHILIPPE reassignment AGRESEARCH LIMITED Alteration of Name(s) of Applicant(s)/Patentee(s) Assignors: HANRAHAN, JAMES, MULSANT, PHILIPPE, NATIONAL UNIVERSITY OF IRELAND, GALWAY, OVITA LIMITED
Application granted granted Critical
Publication of AU2003235525B2 publication Critical patent/AU2003235525B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003235525A 2002-05-30 2003-05-30 New GDF-9 and GDF-9B (BMP-15) sequences for altering mammalian ovarian function and ovulation rate Ceased AU2003235525B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ51933002A NZ519330A (en) 2002-05-30 2002-05-30 New sequences for altering mammalian ovarian function and ovulation rate
NZ519330 2002-05-30
PCT/NZ2003/000109 WO2003102199A1 (fr) 2002-05-30 2003-05-30 Nouvelles sequences gdf-9 et gdf-9b (bmp-15) destinees a modifier la fonction ovarienne et la vitesse d'ovulation chez des mammiferes

Publications (2)

Publication Number Publication Date
AU2003235525A1 AU2003235525A1 (en) 2003-12-19
AU2003235525B2 true AU2003235525B2 (en) 2008-09-11

Family

ID=29707820

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003235525A Ceased AU2003235525B2 (en) 2002-05-30 2003-05-30 New GDF-9 and GDF-9B (BMP-15) sequences for altering mammalian ovarian function and ovulation rate

Country Status (7)

Country Link
EP (1) EP1551973A4 (fr)
JP (1) JP2006510345A (fr)
AU (1) AU2003235525B2 (fr)
BR (1) BR0311465A (fr)
CA (1) CA2490051A1 (fr)
NZ (1) NZ519330A (fr)
WO (1) WO2003102199A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0518900A2 (pt) * 2004-12-02 2008-12-16 Agres Ltd modulaÇço de ovulaÇço
JP2008521891A (ja) * 2004-12-02 2008-06-26 アグリサーチ・リミテッド 排卵の調節
WO2006130022A1 (fr) * 2005-05-30 2006-12-07 Agresearch Limited Modulation de l'ovulation au moyen d'agonistes et d'antagonistes de bmprii
ATE487800T1 (de) * 2005-09-13 2010-11-15 Neocodex S L Verfahren zum in-vitro-nachweis einer veranlagung zur entwicklung von veränderungen der ovarienfunktion
ES2338960B1 (es) * 2007-11-23 2011-04-19 Carnes Oviaragon S.C.L. Procedimiento de mejora de la productividad en ganado ovino.
BRPI0706173C1 (pt) * 2007-11-23 2011-02-22 Brasil Pesquisa Agropec metodo para identificação massal de animais com aumento na prolificidade
WO2014018404A1 (fr) * 2012-07-21 2014-01-30 Baylor College Of Medicine Hétérodimères gdf9/bmp15 pour augmenter la fertilité
CN104774836A (zh) * 2015-04-15 2015-07-15 兰州大学 一种提高绵羊产羔数多基因聚合早期选种的方法
EP3577457A4 (fr) * 2017-02-01 2021-01-20 Robert Bruce Gilchrist Facteurs de croissance sécrétés par les gamètes
CN112601756A (zh) * 2018-05-09 2021-04-02 莫拿什大学 用于增强生育力的剂和方法
CN116649285A (zh) * 2023-05-12 2023-08-29 上海市老年医学中心 一种早发性卵巢功能不全小鼠模型的构建方法及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085926A2 (fr) * 2000-05-05 2001-11-15 Agresearch Limited Sequences nucleotidiques associees a l'augmentation ou a la reduction du taux d'ovulation mammalien
WO2001096393A2 (fr) * 2000-06-15 2001-12-20 Agresearch Limited Sequences de nucleotides et d'acides amines de facteurs derives d'ovocytes permettant de modifier la croissance folliculaire ovarienne in vivoet in vitro

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030617A (en) * 1993-01-12 2000-02-29 The Johns Hopkins University School Of Medicine Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation
EP1181041A2 (fr) * 1999-04-30 2002-02-27 Curis, Inc. Augmentation de fertilite induite par des morphogenes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085926A2 (fr) * 2000-05-05 2001-11-15 Agresearch Limited Sequences nucleotidiques associees a l'augmentation ou a la reduction du taux d'ovulation mammalien
WO2001096393A2 (fr) * 2000-06-15 2001-12-20 Agresearch Limited Sequences de nucleotides et d'acides amines de facteurs derives d'ovocytes permettant de modifier la croissance folliculaire ovarienne in vivoet in vitro

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Accession Data Base number AF078545 *

Also Published As

Publication number Publication date
WO2003102199A1 (fr) 2003-12-11
BR0311465A (pt) 2005-04-05
EP1551973A4 (fr) 2006-06-07
JP2006510345A (ja) 2006-03-30
EP1551973A1 (fr) 2005-07-13
NZ519330A (en) 2004-12-24
CA2490051A1 (fr) 2003-12-11
AU2003235525A1 (en) 2003-12-19

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: OVITA LIMITED; NATIONAL UNIVERSITY OF IRELAND, GAL

Free format text: FORMER APPLICANT(S): OVITA LIMITED; HANRAHAN, JAMES; MULSANT, PHILIPPE; POWELL, RICHARD

PC1 Assignment before grant (sect. 113)

Owner name: NATIONAL UNIVERSITY OF IRELAND, GALWAY; HANRAHAN,

Free format text: FORMER APPLICANT(S): OVITA LIMITED; NATIONAL UNIVERSITY OF IRELAND, GALWAY; HANRAHAN, JAMES; MULSANT, PHILIPPE

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired