AU2005295595C1 - Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders - Google Patents

Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders Download PDF

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Publication number
AU2005295595C1
AU2005295595C1 AU2005295595A AU2005295595A AU2005295595C1 AU 2005295595 C1 AU2005295595 C1 AU 2005295595C1 AU 2005295595 A AU2005295595 A AU 2005295595A AU 2005295595 A AU2005295595 A AU 2005295595A AU 2005295595 C1 AU2005295595 C1 AU 2005295595C1
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Prior art keywords
antibody
cells
seq
cell
binding
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AU2005295595A
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AU2005295595B2 (en
AU2005295595A1 (en
Inventor
Che-Leung Law
Julie Mcearchern
Alan F. Wahl
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Seagen Inc
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Seattle Genetics Inc
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Priority to AU2012200923A priority Critical patent/AU2012200923B2/en
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Publication of AU2005295595C1 publication Critical patent/AU2005295595C1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
AU2005295595A 2004-10-15 2005-10-14 Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders Ceased AU2005295595C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012200923A AU2012200923B2 (en) 2004-10-15 2012-02-17 Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61901804P 2004-10-15 2004-10-15
US60/619,018 2004-10-15
US64535505P 2005-01-19 2005-01-19
US60/645,355 2005-01-19
PCT/US2005/036994 WO2006044643A2 (en) 2004-10-15 2005-10-14 Anti-cd70 antibody and its use for the treatment and prevention of cancer and immune disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012200923A Division AU2012200923B2 (en) 2004-10-15 2012-02-17 Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders

Publications (3)

Publication Number Publication Date
AU2005295595A1 AU2005295595A1 (en) 2006-04-27
AU2005295595B2 AU2005295595B2 (en) 2011-11-17
AU2005295595C1 true AU2005295595C1 (en) 2012-06-21

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AU2005295595A Ceased AU2005295595C1 (en) 2004-10-15 2005-10-14 Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders

Country Status (6)

Country Link
US (4) US7491390B2 (2)
EP (1) EP1799262A4 (2)
JP (2) JP5222559B2 (2)
AU (1) AU2005295595C1 (2)
CA (1) CA2583208C (2)
WO (1) WO2006044643A2 (2)

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US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US20080025989A1 (en) * 2003-02-20 2008-01-31 Seattle Genetics, Inc. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
JP5356648B2 (ja) 2003-02-20 2013-12-04 シアトル ジェネティックス， インコーポレイテッド 抗ｃｄ７０抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
US8337838B2 (en) 2004-10-15 2012-12-25 Seattle Genetics, Inc. Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
US7641903B2 (en) * 2004-10-15 2010-01-05 Seattle Genetics, Inc. Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
WO2006044643A2 (en) 2004-10-15 2006-04-27 Seattle Genetics, Inc. Anti-cd70 antibody and its use for the treatment and prevention of cancer and immune disorders
JP5122441B2 (ja) 2005-04-19 2013-01-16 シアトル ジェネティックス， インコーポレイテッド ヒト化抗ｃｄ７０結合剤およびその使用
ES2708763T3 (es) 2005-07-07 2019-04-11 Seattle Genetics Inc Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
NZ566395A (en) * 2005-09-26 2012-03-30 Medarex Inc Human monoclonal antibodies to CD70
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ES2700141T3 (es) 2007-08-02 2019-02-14 Gilead Biologics Inc Anticuerpos inhibidores LOXL2 y usos de los mismos
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WO2012047732A2 (en) * 2010-09-29 2012-04-12 Genentech, Inc. Antibody compositions and methods of use
KR101847523B1 (ko) 2011-01-24 2018-05-28 연세대학교 산학협력단 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도
EP2686347B1 (en) 2011-03-16 2018-05-02 argenx BVBA Antibodies to cd70
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