AU3353293A - Tie, a novel endothelial cell receptor tyrosine kinase - Google Patents

Tie, a novel endothelial cell receptor tyrosine kinase

Info

Publication number
AU3353293A
AU3353293A AU33532/93A AU3353293A AU3353293A AU 3353293 A AU3353293 A AU 3353293A AU 33532/93 A AU33532/93 A AU 33532/93A AU 3353293 A AU3353293 A AU 3353293A AU 3353293 A AU3353293 A AU 3353293A
Authority
AU
Australia
Prior art keywords
tie
leu
nucleotide
gly
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU33532/93A
Other languages
English (en)
Inventor
Kari Alitalo
Elina Armstrong
Jaana Korhonen
Tomi P Makela
Juha Partanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HELSINKI UNIVERSITY HOLDING Ltd
Original Assignee
Helsinki University Holding Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinki University Holding Ltd filed Critical Helsinki University Holding Ltd
Publication of AU3353293A publication Critical patent/AU3353293A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU33532/93A 1992-01-09 1993-01-08 Tie, a novel endothelial cell receptor tyrosine kinase Abandoned AU3353293A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81780092A 1992-01-09 1992-01-09
US817800 1992-01-09

Publications (1)

Publication Number Publication Date
AU3353293A true AU3353293A (en) 1993-08-03

Family

ID=25223909

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33532/93A Abandoned AU3353293A (en) 1992-01-09 1993-01-08 Tie, a novel endothelial cell receptor tyrosine kinase

Country Status (8)

Country Link
EP (1) EP0620826A1 (fr)
JP (1) JPH07506242A (fr)
KR (1) KR940703857A (fr)
AU (1) AU3353293A (fr)
CA (1) CA2127540A1 (fr)
FI (1) FI943275L (fr)
HU (1) HUT69792A (fr)
WO (1) WO1993014124A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010197A1 (fr) * 1992-10-30 1994-05-11 Ludwig Institute For Cancer Research Nouvelle proteine tyrosine-kinase

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955291A (en) * 1992-01-09 1999-09-21 Alitalo; Kari Antibodies recognizing tie receptor tyrosine kinase and uses thereof
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US6107046A (en) * 1992-10-09 2000-08-22 Orion Corporation Antibodies to Flt4, a receptor tyrosine kinase and uses thereof
US5776755A (en) * 1992-10-09 1998-07-07 Helsinki University Licensing, Ltd. FLT4, a receptor tyrosine kinase
CA2175893C (fr) 1993-11-23 2010-06-22 Paul J. Godowski Tyrosine kinases proteiques appelees rse
US6001621A (en) * 1993-11-23 1999-12-14 Genetech, Inc. Protein tyrosine kinases
US5536641A (en) * 1994-05-17 1996-07-16 Memorial Sloane Kittering Cancer Center Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof for detection of, and isolation of, vascular endothelial cells
US5585269A (en) * 1994-06-02 1996-12-17 The University Of North Carolina At Chapel Hill Isolated DNA encoding c-mer protooncogene
AU694524B2 (en) * 1994-06-09 1998-07-23 Helsinki University Licensing Ltd Oy Flt4 receptor tyrosine kinase and its use in diagnosis and therapy
JPH10506011A (ja) * 1994-09-22 1998-06-16 ヘルシンキ、ユニバーシティ、ライセンシング、リミテッド、オサケ、ユキチュア レセプターチロシンキナーゼ、ｔｉｅのプロモーター
US5722638A (en) * 1995-10-20 1998-03-03 Vemco Corporation Valve with means to block relative rotation of parts during assembly
US5972338A (en) 1997-09-19 1999-10-26 Genentech, Inc. Tie ligands homologues
US6057435A (en) * 1997-09-19 2000-05-02 Genentech, Inc. Tie ligand homologues
US6350450B1 (en) 1997-09-19 2002-02-26 Genentech, Inc. TIE ligand homologue antibody
US6348350B1 (en) 1997-09-19 2002-02-19 Genentech, Inc. Ligand homologues
US6030831A (en) * 1997-09-19 2000-02-29 Genetech, Inc. Tie ligand homologues
US6365154B1 (en) * 1998-09-28 2002-04-02 Smithkline Beecham Corporation Tie2 agonist antibodies
ATE489108T1 (de) 1998-10-09 2010-12-15 Vegenics Ltd Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
US7396810B1 (en) 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US7625859B1 (en) 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
ATE324444T1 (de) 1999-06-07 2006-05-15 Immunex Corp Tek-antagonisten
US6521424B2 (en) 1999-06-07 2003-02-18 Immunex Corporation Recombinant expression of Tek antagonists
DE60043367D1 (de) 1999-06-15 2009-12-31 Genentech Inc Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
CA2435503C (fr) 2001-01-19 2011-02-22 Ludwig Institute For Cancer Research Flt4 (vegfr-3) utilise comme cible pour l'imagerie des tumeurs et le traitement antitumoral
US7871610B2 (en) 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
AU2004266242A1 (en) 2003-08-12 2005-03-03 Dyax Corp. Tie1-binding ligands
US7485297B2 (en) 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody
RS60026B1 (sr) 2013-02-18 2020-04-30 Vegenics Pty Ltd Molekuli koji vezuju ligande i njihove upotrebe

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010197A1 (fr) * 1992-10-30 1994-05-11 Ludwig Institute For Cancer Research Nouvelle proteine tyrosine-kinase

Also Published As

Publication number Publication date
HUT69792A (en) 1995-09-28
WO1993014124A1 (fr) 1993-07-22
JPH07506242A (ja) 1995-07-13
FI943275A0 (fi) 1994-07-08
KR940703857A (ko) 1994-12-12
CA2127540A1 (fr) 1993-07-22
FI943275A7 (fi) 1994-07-11
FI943275L (fi) 1994-07-11
HU9402057D0 (en) 1994-09-28
EP0620826A1 (fr) 1994-10-26

Similar Documents

Publication Publication Date Title
AU3353293A (en) Tie, a novel endothelial cell receptor tyrosine kinase
Partanen et al. A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains
US5776755A (en) FLT4, a receptor tyrosine kinase
AU700915B2 (en) Lung cancer marker
EP0842273B1 (fr) Facteur de croissance endothelial vasculaire (vegf-c) en tant que ligand de recepteur
US5607918A (en) Vascular endothelial growth factor-B and DNA coding therefor
Treves et al. Molecular cloning, expression, functional characterization, chromosomal localization, and gene structure of junctate, a novel integral calcium binding protein of sarco (endo) plasmic reticulum membrane
AU2163592A (en) A novel receptor-type tyrosine kinase and use thereof
US7297493B2 (en) Fibroblast growth factor receptor activating gene 1 and related compositions and methods
WO1999007893A1 (fr) ISOLEMENT D'UN NOUVEAU GENE p23 DU FACTEUR DE SENESCENCE
WO1997032020A9 (fr) Proteines shc
EP0996628A2 (fr) Proteine de mammifere de type facteur de croissance nerveuse
US6340575B1 (en) Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity
US6005089A (en) Platelet glycoprotein V gene and uses
Halford et al. Genomic structure and expression of the mouse growth factor receptor related to tyrosine kinases (Ryk)
US6107472A (en) Receptor-type tyrosine kinase-like molecules
CA2101632A1 (fr) Recepteurs pour facteur de croissance d'origine plaquettaire
US5912142A (en) Gene product over expressed in cancer cells
EP0707648A1 (fr) Gene de la glycoproteine v des plaquettes et utilisations de ce gene
AU3373299A (en) Mammalian blood loss-induced gene, kd312
US20030228587A1 (en) Nucleic acid molecule encoding IWU-1
HK1014984B (en) Receptor ligand vegf-c
AU2007202554A1 (en) Receptor Ligand VEGF-C
HUP0002541A2 (hu) Emlőscitokin-szerű 7-es faktor