AU555961B2 - 1-substituted n-(8alpha-ergolinyl)-n:,n:-diethylureas - Google Patents

1-substituted n-(8alpha-ergolinyl)-n:,n:-diethylureas

Info

Publication number
AU555961B2
AU555961B2 AU12167/83A AU1216783A AU555961B2 AU 555961 B2 AU555961 B2 AU 555961B2 AU 12167/83 A AU12167/83 A AU 12167/83A AU 1216783 A AU1216783 A AU 1216783A AU 555961 B2 AU555961 B2 AU 555961B2
Authority
AU
Australia
Prior art keywords
diethylureas
ergolinyl
8alpha
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU12167/83A
Other languages
English (en)
Other versions
AU1216783A (en
Inventor
Antonin Cerny
Jiri Krepelka
Karel Rezabek
Miroslav Seda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Original Assignee
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Podniky Pro Zdravotnickou Vyrobu, Spofa Vereinigte Pharma Werke filed Critical Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Publication of AU1216783A publication Critical patent/AU1216783A/en
Application granted granted Critical
Publication of AU555961B2 publication Critical patent/AU555961B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU12167/83A 1982-03-12 1983-03-08 1-substituted n-(8alpha-ergolinyl)-n:,n:-diethylureas Ceased AU555961B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Publications (2)

Publication Number Publication Date
AU1216783A AU1216783A (en) 1983-09-15
AU555961B2 true AU555961B2 (en) 1986-10-16

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12167/83A Ceased AU555961B2 (en) 1982-03-12 1983-03-08 1-substituted n-(8alpha-ergolinyl)-n:,n:-diethylureas

Country Status (15)

Country Link
JP (1) JPS58180484A (da)
AT (1) AT383349B (da)
AU (1) AU555961B2 (da)
BE (1) BE896122A (da)
CA (1) CA1203531A (da)
CH (1) CH652125A5 (da)
CS (1) CS231214B1 (da)
DE (1) DE3308719A1 (da)
DK (1) DK84683A (da)
FI (1) FI830754A7 (da)
FR (1) FR2523131B1 (da)
GB (1) GB2116548B (da)
IT (1) IT1161209B (da)
NL (1) NL8300829A (da)
SE (1) SE452321B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3623503A1 (de) * 1986-07-09 1988-01-21 Schering Ag 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne
CN103476402A (zh) * 2010-11-11 2013-12-25 西诺克萨医药有限公司 用于预防和/或治疗纤维化病变的麦角乙脲、特麦角脲及其衍生物
JP6856532B2 (ja) 2015-01-20 2021-04-07 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ エルゴリン化合物およびその使用
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
EP3630758A1 (en) 2017-06-01 2020-04-08 Xoc Pharmaceuticals, Inc Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
AT231082B (de) * 1960-10-12 1964-01-10 Sandoz Ag Verfahren zur Herstellung von neuen Harnstoff-Derivaten
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
CH652125A5 (de) 1985-10-31
GB2116548A (en) 1983-09-28
AT383349B (de) 1987-06-25
CS231214B1 (en) 1984-10-15
FI830754L (fi) 1983-09-13
IT8319935A0 (it) 1983-03-07
FI830754A0 (fi) 1983-03-07
CA1203531A (en) 1986-04-22
DK84683D0 (da) 1983-02-24
FR2523131A1 (fr) 1983-09-16
GB8305735D0 (en) 1983-04-07
ATA72783A (de) 1986-11-15
DK84683A (da) 1983-09-13
AU1216783A (en) 1983-09-15
GB2116548B (en) 1985-03-20
BE896122A (fr) 1983-07-01
SE8301257D0 (sv) 1983-03-08
IT1161209B (it) 1987-03-18
SE8301257L (sv) 1983-09-13
FR2523131B1 (fr) 1987-08-28
NL8300829A (nl) 1983-10-03
SE452321B (sv) 1987-11-23
DE3308719A1 (de) 1983-09-22
JPS58180484A (ja) 1983-10-21
FI830754A7 (fi) 1983-09-13

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