AU711207B2 - Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haemopoietic cell system - Google Patents

Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haemopoietic cell system Download PDF

Info

Publication number: AU711207B2
Authority: AU; Australia
Prior art keywords: flupirtine; cells; prophylaxis; impairment; cell system
Prior art date: 1995-11-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU17165/97A

Other languages

English (en)

Other versions

AU1716597A (en

Inventor

Werner E. G. Muller

Gabriela Pergande

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Meda Pharma GmbH and Co KG

Original Assignee

Asta Medica GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-07

Filing date

1996-10-23

Publication date

1999-10-07

1996-10-23 Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH

1997-05-29 Publication of AU1716597A publication Critical patent/AU1716597A/en

1999-10-07 Application granted granted Critical

1999-10-07 Publication of AU711207B2 publication Critical patent/AU711207B2/en

2002-03-28 Assigned to VIATRIS GMBH & CO. KG reassignment VIATRIS GMBH & CO. KG Alteration of Name(s) in Register under S187 Assignors: ASTA MEDICA AKTIENGESELLSCHAFT

2016-10-23 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Virology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Polyurethanes Or Polyureas (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyridine Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AU17165/97A 1995-11-07 1996-10-23 Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haemopoietic cell system Ceased AU711207B2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19541405A DE19541405A1 (de)	1995-11-07	1995-11-07	Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
DE19541405		1995-11-07
PCT/DE1996/002009 WO1997017072A2 (de)	1995-11-07	1996-10-23	Verwendung von flupirtin zur prophylaxe und therapie von erkrankungen, die mit einer beeinträchtigung des hämatopoetischen zellsystems einhergehen

Publications (2)

Publication Number	Publication Date
AU1716597A AU1716597A (en)	1997-05-29
AU711207B2 true AU711207B2 (en)	1999-10-07

Family

ID=7776799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU17165/97A Ceased AU711207B2 (en)	1995-11-07	1996-10-23	Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haemopoietic cell system

Country Status (26)

Country	Link
US (2)	US6034111A (de)
EP (1)	EP0859613B1 (de)
JP (1)	JPH11514652A (de)
KR (1)	KR100512673B1 (de)
CN (1)	CN1116037C (de)
AT (1)	ATE316789T1 (de)
AU (1)	AU711207B2 (de)
BG (1)	BG63149B1 (de)
BR (1)	BR9611588A (de)
CA (1)	CA2189705C (de)
CZ (1)	CZ298115B6 (de)
DE (2)	DE19541405A1 (de)
DK (1)	DK0859613T3 (de)
ES (1)	ES2257755T3 (de)
HU (1)	HU225742B1 (de)
MX (1)	MX9803610A (de)
NO (1)	NO315074B1 (de)
NZ (1)	NZ330414A (de)
PL (1)	PL186537B1 (de)
PT (1)	PT859613E (de)
RU (1)	RU2200555C2 (de)
SK (1)	SK284601B6 (de)
TW (1)	TW393317B (de)
UA (1)	UA51682C2 (de)
WO (1)	WO1997017072A2 (de)
ZA (1)	ZA968783B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19625582A1 (de) *	1996-06-27	1998-01-02	Asta Medica Ag	Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen
US6821995B1 (en)	1999-12-01	2004-11-23	Duke University	Method of treating batten disease
DE10327674A1 (de)	2003-06-20	2005-01-05	Awd.Pharma Gmbh & Co. Kg	Injizierbare Darreichungsform von Flupirtin
EP1688141A1 (de) *	2005-01-31	2006-08-09	elbion AG	Verwendung von Flupirtine zur Behandlung der hyperaktiven Blase und damit zusammenhängender Erkrankungen und zur Behandlung des Reizdarmsyndroms
US20080279930A1 (en) *	2007-05-07	2008-11-13	Bernd Terhaag	Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
DE102009023162B4 (de) *	2009-05-29	2011-07-07	Corden PharmaChem GmbH, 68305	Verfahren zur Herstellung von Flupirtin
JP5650739B2 (ja) *	2009-08-07	2015-01-07	スウエイジロク・カンパニー	低真空下での低温浸炭
DE102010030053A1 (de)	2010-06-14	2011-12-15	Awd.Pharma Gmbh & Co.Kg	Injizierbare Darreichungsform von Flupirtin
CN104302277A (zh) *	2012-03-02	2015-01-21	Meda制药有限及两合公司	含有氟吡汀的药物制剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7652894A (en) *	1993-08-17	1995-03-14	Meda Pharma Gmbh & Co. Kg	The primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN172468B (de) *	1990-07-14	1993-08-14	Asta Medica Ag

1995
- 1995-11-07 DE DE19541405A patent/DE19541405A1/de not_active Ceased
1996
- 1996-10-18 ZA ZA968783A patent/ZA968783B/xx unknown
- 1996-10-23 EP EP96945822A patent/EP0859613B1/de not_active Expired - Lifetime
- 1996-10-23 UA UA98062946A patent/UA51682C2/uk unknown
- 1996-10-23 RU RU98111152/14A patent/RU2200555C2/ru not_active IP Right Cessation
- 1996-10-23 PL PL96326629A patent/PL186537B1/pl not_active IP Right Cessation
- 1996-10-23 PT PT96945822T patent/PT859613E/pt unknown
- 1996-10-23 DK DK96945822T patent/DK0859613T3/da active
- 1996-10-23 HU HU9901659A patent/HU225742B1/hu not_active IP Right Cessation
- 1996-10-23 JP JP9517734A patent/JPH11514652A/ja active Pending
- 1996-10-23 AT AT96945822T patent/ATE316789T1/de active
- 1996-10-23 KR KR10-1998-0703376A patent/KR100512673B1/ko not_active Expired - Fee Related
- 1996-10-23 CN CN96198131A patent/CN1116037C/zh not_active Expired - Fee Related
- 1996-10-23 ES ES96945822T patent/ES2257755T3/es not_active Expired - Lifetime
- 1996-10-23 DE DE59611327T patent/DE59611327D1/de not_active Expired - Lifetime
- 1996-10-23 WO PCT/DE1996/002009 patent/WO1997017072A2/de not_active Ceased
- 1996-10-23 SK SK586-98A patent/SK284601B6/sk not_active IP Right Cessation
- 1996-10-23 AU AU17165/97A patent/AU711207B2/en not_active Ceased
- 1996-10-23 CZ CZ0128398A patent/CZ298115B6/cs not_active IP Right Cessation
- 1996-10-23 NZ NZ330414A patent/NZ330414A/en unknown
- 1996-10-23 BR BR9611588A patent/BR9611588A/pt not_active Application Discontinuation
- 1996-11-04 TW TW085113437A patent/TW393317B/zh not_active IP Right Cessation
- 1996-11-06 CA CA002189705A patent/CA2189705C/en not_active Expired - Fee Related
- 1996-11-07 US US08/744,953 patent/US6034111A/en not_active Expired - Lifetime
1998
- 1998-04-16 US US09/061,099 patent/US6034112A/en not_active Expired - Lifetime
- 1998-04-24 BG BG102404A patent/BG63149B1/bg unknown
- 1998-04-27 NO NO19981898A patent/NO315074B1/no not_active IP Right Cessation
- 1998-05-07 MX MX9803610A patent/MX9803610A/es not_active IP Right Cessation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7652894A (en) *	1993-08-17	1995-03-14	Meda Pharma Gmbh & Co. Kg	The primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EUR. JNL. OF PHAR. VOL317 NO1 12/12/96 PROVIC ETAL PP.157-64 *
SOC. FOR NEUROSCIENCE ABST. VOL20 NO1-2 '94 MULLER ETAL P451 *

Also Published As

Publication number	Publication date
RU2200555C2 (ru)	2003-03-20
DE19541405A1 (de)	1997-05-15
KR19990067366A (ko)	1999-08-16
BG63149B1 (bg)	2001-05-31
NO981898D0 (no)	1998-04-27
HUP9901659A2 (hu)	1999-09-28
WO1997017072A2 (de)	1997-05-15
CZ128398A3 (cs)	1998-09-16
EP0859613A2 (de)	1998-08-26
CZ298115B6 (cs)	2007-06-27
DK0859613T3 (da)	2006-06-06
ZA968783B (en)	1997-05-27
BG102404A (en)	1998-12-30
PL326629A1 (en)	1998-10-12
MX9803610A (es)	1998-09-30
ES2257755T3 (es)	2006-08-01
SK58698A3 (en)	1998-09-09
NZ330414A (en)	1999-10-28
NO981898L (no)	1998-04-27
AU1716597A (en)	1997-05-29
KR100512673B1 (ko)	2005-12-09
CA2189705A1 (en)	1997-05-08
HU225742B1 (en)	2007-07-30
UA51682C2 (uk)	2002-12-16
JPH11514652A (ja)	1999-12-14
DE59611327D1 (de)	2006-04-13
HK1016508A1 (en)	1999-11-05
ATE316789T1 (de)	2006-02-15
PL186537B1 (pl)	2004-01-30
BR9611588A (pt)	1999-04-06
US6034112A (en)	2000-03-07
HUP9901659A3 (en)	2001-04-28
CN1201391A (zh)	1998-12-09
SK284601B6 (sk)	2005-07-01
CN1116037C (zh)	2003-07-30
WO1997017072A3 (de)	1997-07-24
US6034111A (en)	2000-03-07
CA2189705C (en)	2005-08-09
PT859613E (pt)	2006-06-30
EP0859613B1 (de)	2006-02-01
TW393317B (en)	2000-06-11
NO315074B1 (no)	2003-07-07

Legal Events

Date

Code

Title

Description

2002-03-28

PC

Assignment registered

Owner name: VIATRIS GMBH AND CO. KG

Free format text: FORMER OWNER WAS: ASTA MEDICA AKTIENGESELLSCHAFT

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DK175582B1 (da)	2004-12-13	Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion
Huang et al.	2000	Effects of extracellular human immunodeficiency virus type 1 vpr protein in primary rat cortical cell cultures
US6034111A (en)	2000-03-07	Use of flupirtine for the prophylaxis and therapy of diseases associated with an impairment of the haematopoetic cell system
WO2000044381A1 (en)	2000-08-03	Treatment of lymphomas, leukemias, and leiomyomas
Fantini et al.	1990	Suramin inhibits proliferation of rat glioma cells and alters N‐cam cell surface expression
SK24098A3 (en)	1998-09-09	Combinatory composition for the treatment of dementia
WO1997017072A9 (de)	1997-08-21	Verwendung von flupirtin zur prophylaxe und therapie von erkrankungen, die mit einer beeinträchtigung des hämatopoetischen zellsystems einhergehen
FR2791891A1 (fr)	2000-10-13	Utilisation de la tianeptine pour l'obtention de medicaments destines au traitement des pathologies de la neurodegenerescence
EP3989961B1 (de)	2023-11-22	Pharmazeutische kombination aus einer artemisinin-verbindung und einem häme-synthese-modulator zur behandlung von krebs
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Müller et al.	1997	Flupirtine protects both neuronal cells and lymphocytes against induced apoptosis in vitro: implications for treatment of AIDS patients
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MXPA98008661A (en)	1999-04-27	Benzamide treatment of associated dementia the infection for the virus of the acquired immunodeficiency syndrome (human immunodeficiency virus)
CA2041884A1 (en)	1991-11-05	Process for the selective modulation of the expression and function of a determinant on the cell surface by means of appropriate chemical agents