AU718436B2 - Synthetic peptides and pharmaceutical compositions comprising them - Google Patents

Synthetic peptides and pharmaceutical compositions comprising them Download PDF

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Publication number
AU718436B2
AU718436B2 AU59095/96A AU5909596A AU718436B2 AU 718436 B2 AU718436 B2 AU 718436B2 AU 59095/96 A AU59095/96 A AU 59095/96A AU 5909596 A AU5909596 A AU 5909596A AU 718436 B2 AU718436 B2 AU 718436B2
Authority
AU
Australia
Prior art keywords
peptide
seq
amino acid
response
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU59095/96A
Other languages
English (en)
Other versions
AU5909596A (en
Inventor
Edna Mozes
Michael Sela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of AU5909596A publication Critical patent/AU5909596A/en
Application granted granted Critical
Publication of AU718436B2 publication Critical patent/AU718436B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
AU59095/96A 1995-06-07 1996-06-06 Synthetic peptides and pharmaceutical compositions comprising them Ceased AU718436B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/475577 1995-06-07
US08/475,577 US6066621A (en) 1989-12-10 1995-06-07 Synthetic peptides for the treatment of myasthenia gravis
PCT/IL1996/000005 WO1996040777A2 (fr) 1995-06-07 1996-06-06 Peptides synthetiques et compositions pharmaceutiques contenant ces peptides

Publications (2)

Publication Number Publication Date
AU5909596A AU5909596A (en) 1996-12-30
AU718436B2 true AU718436B2 (en) 2000-04-13

Family

ID=23888200

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59095/96A Ceased AU718436B2 (en) 1995-06-07 1996-06-06 Synthetic peptides and pharmaceutical compositions comprising them

Country Status (9)

Country Link
US (1) US6066621A (fr)
EP (1) EP0832127B1 (fr)
JP (1) JP4065322B2 (fr)
AT (1) ATE192164T1 (fr)
AU (1) AU718436B2 (fr)
CA (1) CA2221646A1 (fr)
DE (1) DE69607962T2 (fr)
IL (1) IL122443A (fr)
WO (1) WO1996040777A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911526B2 (en) * 1996-07-22 2005-06-28 The Trustees Of Columbia University In The City Of New York Compounds that inhibit the interaction between signal-transducing proteins and the GLGF (PDZ/DHR) domain and uses thereof
WO2000005249A2 (fr) 1998-07-23 2000-02-03 The President And Fellows Of Harvard College Peptides synthetiques et procedes d'utilisation de ceux-ci dans des therapies de maladies auto-immunes
CA2405484A1 (fr) * 2000-03-31 2001-10-11 Corixa Corporation Identification de peptides immunodominants potentiels de sous-unites alpha du recepteur de l'acetylcholine
US7273722B2 (en) * 2000-11-29 2007-09-25 Allergan, Inc. Neurotoxins with enhanced target specificity
IL141647A0 (en) * 2001-02-26 2002-03-10 Yeda Res & Dev Synthetic human peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
WO2022260579A2 (fr) 2021-06-07 2022-12-15 Toleranzia Ab Protéine de fusion dans la myasthénie grave
TW202444434A (zh) * 2023-03-24 2024-11-16 美商庫爾製藥發展公司股份有限公司 用於重症肌無力治療之免疫修飾奈米粒子之處理

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340012C (fr) * 1987-08-17 1998-08-25 Trustees Of Leland Stanford Jr. University Determinant peptidique associe a l'immunite
IL92629A0 (en) * 1989-12-10 1990-08-31 Yeda Res & Dev Direct binding of t-cell epitopes to mhc gene products on intact living antigen presenting cells and the use thereof for identifying epitopes causing autoimmune diseases and pharmaceutical compositions for treating such diseases
US5116944A (en) * 1989-12-29 1992-05-26 Neorx Corporation Conjugates having improved characteristics for in vivo administration
IL122445A0 (en) * 1992-06-18 1998-06-15 Yeda Res & Dev Peptide polymers and pharmaceutical compositions comprising them for treatment of myasthenia gravis

Also Published As

Publication number Publication date
WO1996040777A3 (fr) 1997-01-23
EP0832127B1 (fr) 2000-04-26
US6066621A (en) 2000-05-23
JP4065322B2 (ja) 2008-03-26
DE69607962T2 (de) 2000-12-07
DE69607962D1 (de) 2000-05-31
EP0832127A2 (fr) 1998-04-01
WO1996040777A2 (fr) 1996-12-19
IL122443A0 (en) 1998-06-15
CA2221646A1 (fr) 1996-12-19
JPH11507620A (ja) 1999-07-06
IL122443A (en) 2007-10-31
AU5909596A (en) 1996-12-30
ATE192164T1 (de) 2000-05-15

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Legal Events

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FGA Letters patent sealed or granted (standard patent)