AU8399801A - Tetrazolyl-phenyl acetamide glucokinase activators - Google Patents

Tetrazolyl-phenyl acetamide glucokinase activators

Info

Publication number: AU8399801A
Authority: AU; Australia
Prior art keywords: tetrazolyl; glucokinase activators; phenyl acetamide; acetamide glucokinase; phenyl
Prior art date: 2000-08-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

AU8399801A

Other languages

English (en)

Inventor

Achyutharao Sidduri

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-15

Filing date

2001-08-09

Publication date

2002-02-25

2001-08-09 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2002-02-25 Publication of AU8399801A publication Critical patent/AU8399801A/xx

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU8399801A 2000-08-15 2001-08-09 Tetrazolyl-phenyl acetamide glucokinase activators Pending AU8399801A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22549400P	2000-08-15	2000-08-15
PCT/EP2001/009207 WO2002014312A1 (en)	2000-08-15	2001-08-09	Tetrazolyl-phenyl acetamide glucokinase activators

Publications (1)

Publication Number	Publication Date
AU8399801A true AU8399801A (en)	2002-02-25

Family

ID=22845106

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU8399801A Pending AU8399801A (en)	2000-08-15	2001-08-09	Tetrazolyl-phenyl acetamide glucokinase activators
AU2001283998A Ceased AU2001283998B2 (en)	2000-08-15	2001-08-09	Tetrazolyl-phenyl acetamide glucokinase activators

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2001283998A Ceased AU2001283998B2 (en)	2000-08-15	2001-08-09	Tetrazolyl-phenyl acetamide glucokinase activators

Country Status (20)

Country	Link
US (3)	US6369232B1 (2)
EP (1)	EP1311504B1 (2)
JP (1)	JP3961948B2 (2)
KR (1)	KR100518061B1 (2)
CN (1)	CN1209362C (2)
AR (1)	AR031718A1 (2)
AT (1)	ATE297921T1 (2)
AU (2)	AU8399801A (2)
BR (1)	BR0113312A (2)
CA (1)	CA2419416C (2)
DE (1)	DE60111540T2 (2)
DK (1)	DK1311504T3 (2)
ES (1)	ES2243541T3 (2)
MX (1)	MXPA03001275A (2)
PA (1)	PA8525201A1 (2)
PE (1)	PE20020386A1 (2)
PT (1)	PT1311504E (2)
UY (1)	UY26885A1 (2)
WO (1)	WO2002014312A1 (2)
ZA (1)	ZA200300904B (2)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0102299D0 (sv)	2001-06-26	2001-06-26	Astrazeneca Ab	Compounds
SE0102764D0 (sv)	2001-08-17	2001-08-17	Astrazeneca Ab	Compounds
US7078423B2 (en) *	2002-07-18	2006-07-18	Inotek Pharmaceuticals Corporation	5-Aryltetrazole compounds, compositions thereof, and uses therefor
US7087631B2 (en) *	2002-07-18	2006-08-08	Inotek Pharmaceuticals Corporation	Aryltetrazole compounds, and compositions thereof
BR0314864A (pt)	2002-10-03	2005-08-02	Novartis Ag	Compostos orgânicos
GB0226931D0 (en)	2002-11-19	2002-12-24	Astrazeneca Ab	Chemical compounds
MY141521A (en)	2002-12-12	2010-05-14	Hoffmann La Roche	5-substituted-six-membered heteroaromatic glucokinase activators
AU2003294376A1 (en) *	2003-01-06	2004-08-10	Eli Lilly And Company	Heteroaryl compounds
PL378117A1 (pl) *	2003-02-11	2006-03-06	Prosidion Limited	Tricyklopodstawione związki amidowe
US7262196B2 (en) *	2003-02-11	2007-08-28	Prosidion Limited	Tri(cyclo) substituted amide glucokinase activator compounds
BRPI0509573A (pt)	2004-04-02	2007-09-25	Novartis Ag	derivados de sulfonamida-tiazolpiridina como ativadores de glicocinase úteis para o tratamento de diabetes do tipo 2
US7781451B2 (en)	2004-04-02	2010-08-24	Novartis Ag	Thiazolopyridine derivatives, pharmaceut ical conditions containing them and methods of treating glucokinase mediated conditions
KR101346902B1 (ko)	2005-07-09	2014-01-02	아스트라제네카 아베	당뇨병 치료에 있어 ｇｌｋ 활성화제로서 사용하기 위한헤테로아릴 벤즈아미드 유도체
JP4033409B1 (ja) *	2005-07-11	2008-01-16	田辺三菱製薬株式会社	オキシム誘導体及びその製法
WO2007026761A1 (ja)	2005-08-31	2007-03-08	Astellas Pharma Inc.	チアゾール誘導体
JP2007063225A (ja) *	2005-09-01	2007-03-15	Takeda Chem Ind Ltd	イミダゾピリジン化合物
CA2624102A1 (en)	2005-09-29	2007-04-12	Sanofi-Aventis	Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
GT200600428A (es)	2005-09-30	2007-05-21		Compuestos organicos
GT200600429A (es)	2005-09-30	2007-04-30		Compuestos organicos
WO2007051845A1 (en) *	2005-11-03	2007-05-10	Prosidion Ltd	Tricyclo substituted amides
EP1948614A2 (en) *	2005-11-18	2008-07-30	Takeda San Diego, Inc.	Glucokinase activators
ES2381864T3 (es) *	2005-12-15	2012-06-01	Nihon Nohyaku Co., Ltd.	Derivado de ftalamida, pesticida agrícola u hortícola y utilización del pesticida
EP2001875A2 (en)	2006-03-08	2008-12-17	Takeda San Diego, Inc.	Glucokinase activators
PE20080251A1 (es)	2006-05-04	2008-04-25	Boehringer Ingelheim Int	Usos de inhibidores de dpp iv
EP2049518B1 (en) *	2006-05-31	2011-08-31	Takeda San Diego, Inc.	Indazole and isoindole derivatives as glucokinase activating agents.
US7910747B2 (en) *	2006-07-06	2011-03-22	Bristol-Myers Squibb Company	Phosphonate and phosphinate pyrazolylamide glucokinase activators
US7902248B2 (en)	2006-12-14	2011-03-08	Hoffmann-La Roche Inc.	Oxime glucokinase activators
US8163779B2 (en)	2006-12-20	2012-04-24	Takeda San Diego, Inc.	Glucokinase activators
TW200831081A (en)	2006-12-25	2008-08-01	Kyorin Seiyaku Kk	Glucokinase activator
EP2105435A4 (en)	2007-01-10	2011-06-15	Mitsubishi Tanabe Pharma Corp	Hydrazone derivative
JP5248477B2 (ja)	2007-03-07	2013-07-31	杏林製薬株式会社	グルコキナーゼ活性化物質
US8173645B2 (en) *	2007-03-21	2012-05-08	Takeda San Diego, Inc.	Glucokinase activators
JP5580201B2 (ja) *	2007-10-08	2014-08-27	アドビヌス・セラピューティクス・プライベート・リミテッド	グルコキナーゼアクチベータとしてのアセトアミド誘導体、その製法及び医薬応用
TW200934772A (en) *	2008-01-15	2009-08-16	Lilly Co Eli	Crystalline(R)-2-(4-cyclopropanesulphonyl-phenyl)-N-pyrazin-2-yl-3-(tetrahydropyran-4-yl)-propionamide
JP5287730B2 (ja) *	2008-01-18	2013-09-11	アステラス製薬株式会社	フェニルアセトアミド誘導体
KR101608259B1 (ko)	2008-04-28	2016-04-01	교린 세이야꾸 가부시키 가이샤	시클로펜틸아크릴산아미드 유도체
CN102959076B (zh)	2010-03-31	2015-09-16	斯克里普斯研究所	重编程细胞

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3776917A (en) *	1972-06-05	1973-12-04	Schering Corp	2-amino-6-phenalkyl-aminopyridines and derivatives thereof
GB8909574D0 (en)	1989-04-26	1989-06-14	Ici Plc	Chemical process
US5859052A (en) *	1993-01-14	1999-01-12	G. D. Searle & Co.	Fatty acid analogs and prodrugs
US5468867A (en) *	1994-05-27	1995-11-21	Syntex (U.S.A.) Inc.	Process for preparing1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl1-1H-indole-3-carboxylic acid
US5461049A (en) *	1994-05-27	1995-10-24	Warner-Lambert Company	Amide tetrazole ACAT inhibitors
ID22273A (id) *	1997-01-28	1999-09-23	Merck & Co Inc	TIAZOL BENZENASULFONAMIDA SEBAGAI AGONIS β UNTUK PENGOBATAN DIABETES DAN OBESITAS
PL350669A1 (en) *	1999-03-29	2003-01-27	Hoffmann La Roche	Glucokinase activators

2001
- 2001-08-08 US US09/924,247 patent/US6369232B1/en not_active Expired - Fee Related
- 2001-08-09 AU AU8399801A patent/AU8399801A/xx active Pending
- 2001-08-09 CN CNB018163475A patent/CN1209362C/zh not_active Expired - Fee Related
- 2001-08-09 MX MXPA03001275A patent/MXPA03001275A/es active IP Right Grant
- 2001-08-09 AT AT01962926T patent/ATE297921T1/de not_active IP Right Cessation
- 2001-08-09 KR KR10-2003-7002231A patent/KR100518061B1/ko not_active Expired - Fee Related
- 2001-08-09 WO PCT/EP2001/009207 patent/WO2002014312A1/en not_active Ceased
- 2001-08-09 ES ES01962926T patent/ES2243541T3/es not_active Expired - Lifetime
- 2001-08-09 PT PT01962926T patent/PT1311504E/pt unknown
- 2001-08-09 AU AU2001283998A patent/AU2001283998B2/en not_active Ceased
- 2001-08-09 CA CA002419416A patent/CA2419416C/en not_active Expired - Fee Related
- 2001-08-09 BR BR0113312-8A patent/BR0113312A/pt not_active IP Right Cessation
- 2001-08-09 JP JP2002519452A patent/JP3961948B2/ja not_active Expired - Fee Related
- 2001-08-09 EP EP01962926A patent/EP1311504B1/en not_active Expired - Lifetime
- 2001-08-09 DK DK01962926T patent/DK1311504T3/da active
- 2001-08-09 DE DE60111540T patent/DE60111540T2/de not_active Expired - Lifetime
- 2001-08-14 PA PA20018525201A patent/PA8525201A1/es unknown
- 2001-08-14 UY UY26885A patent/UY26885A1/es not_active Application Discontinuation
- 2001-08-14 AR ARP010103886A patent/AR031718A1/es active IP Right Grant
- 2001-08-15 PE PE2001000814A patent/PE20020386A1/es not_active Application Discontinuation
- 2001-10-11 US US09/975,713 patent/US6388088B1/en not_active Expired - Fee Related
2002
- 2002-01-16 US US10/050,508 patent/US6441180B1/en not_active Expired - Fee Related
2003
- 2003-01-31 ZA ZA200300904A patent/ZA200300904B/en unknown

Also Published As

Publication number	Publication date
WO2002014312A1 (en)	2002-02-21
ATE297921T1 (de)	2005-07-15
MXPA03001275A (es)	2003-06-30
UY26885A1 (es)	2002-02-28
CA2419416A1 (en)	2002-02-21
CN1209362C (zh)	2005-07-06
US6441180B1 (en)	2002-08-27
PE20020386A1 (es)	2002-05-13
KR20030022408A (ko)	2003-03-15
AU2001283998B2 (en)	2005-10-20
DE60111540D1 (de)	2005-07-21
JP3961948B2 (ja)	2007-08-22
ZA200300904B (en)	2004-04-30
AR031718A1 (es)	2003-10-01
US6388088B1 (en)	2002-05-14
KR100518061B1 (ko)	2005-09-28
JP2004506632A (ja)	2004-03-04
EP1311504A1 (en)	2003-05-21
US20020065275A1 (en)	2002-05-30
BR0113312A (pt)	2003-07-01
US6369232B1 (en)	2002-04-09
PT1311504E (pt)	2005-10-31
US20020035267A1 (en)	2002-03-21
PA8525201A1 (es)	2002-07-30
DE60111540T2 (de)	2006-03-16
CA2419416C (en)	2009-10-13
CN1466584A (zh)	2004-01-07
ES2243541T3 (es)	2005-12-01
EP1311504B1 (en)	2005-06-15
US20020035266A1 (en)	2002-03-21
DK1311504T3 (da)	2005-10-17

Publication	Publication Date	Title
AU8399801A (en)	2002-02-25	Tetrazolyl-phenyl acetamide glucokinase activators
AU5227001A (en)	2001-11-12	Hydantoin-containing glucokinase activators
AU8760001A (en)	2002-02-05	Alpha-acyl and alpha-heteroatom-substituted benzene acetamide glucokinase activators
EG23870A (en)	2007-11-27	Glucokinase activators
IL145322A0 (en)	2002-06-30	Glucokinase activators
AU6591401A (en)	2001-11-20	Para-amine substituted phenylamide glucokinase activators
TW527915U (en)	2003-04-11	Absorbent article
SG94777A1 (en)	2003-03-18	Absorbent article
SG91901A1 (en)	2002-10-15	Absorbent article
AU6447101A (en)	2001-12-24	Absorbent article
SG94357A1 (en)	2003-02-18	Absorbent article
PL366038A1 (en)	2005-01-24	Nucleoside compounds and uses thereof
HUP0402552A3 (en)	2005-05-30	Absorbent article
AU154409S (en)	2004-02-03	Absorbent article
DK1242397T3 (da)	2006-02-13	Trans-olefiniske glucokinaseaktivatorer
TW502617U (en)	2002-09-11	Absorbent article
SG99892A1 (en)	2003-11-27	Absorbent article
TW493428U (en)	2002-07-01	Absorbent article
TW493429U (en)	2002-07-01	Absorbent article
SG108287A1 (en)	2005-01-28	Absorbent article
PL368975A1 (en)	2005-04-04	Absorbent article with improved fit
TW481982U (en)	2002-04-01	Absorbent article
GB0221620D0 (en)	2002-10-30	Absorbent articles
GB0013870D0 (en)	2000-08-02	Foamed ceramics
GB0103038D0 (en)	2001-03-21	Absorbent article