BE1000245A3 - Nouveaux derives de la purine, leur preparation et leur utilisation comme medicaments. - Google Patents

Nouveaux derives de la purine, leur preparation et leur utilisation comme medicaments. Download PDF

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Publication number
BE1000245A3
BE1000245A3 BE8700113A BE8700113A BE1000245A3 BE 1000245 A3 BE1000245 A3 BE 1000245A3 BE 8700113 A BE8700113 A BE 8700113A BE 8700113 A BE8700113 A BE 8700113A BE 1000245 A3 BE1000245 A3 BE 1000245A3
Authority
BE
Belgium
Prior art keywords
amino
medicaments
preparation
group
purine derivatives
Prior art date
Application number
BE8700113A
Other languages
English (en)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Application granted granted Critical
Publication of BE1000245A3 publication Critical patent/BE1000245A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention a pour objet les composés de formule dans laquelle R représente un groupe diphénylalkyle éventuellement substitué, R1 représente l'hydrogène, un halogène, un groupe amino, alkylamino, dialkylamino, 1-pipéridino, alcanoylamino, hydroxy, alcoxy, mercapto, alkylthio, benzoylamino ou pyridinylcarbonyl-amino, R2 représente l'hydrogène ou un groupe hydroxy, amino ou alcanoylamino et R3 représente l'hydrogène, un halogène ou un groupe alkyle, trifluorométhyle ou amino. Ces composés peuvent etre utilisés comme médicaments.
BE8700113A 1986-02-14 1987-02-12 Nouveaux derives de la purine, leur preparation et leur utilisation comme medicaments. BE1000245A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3604743 1986-02-14
DE3612953 1986-04-17

Publications (1)

Publication Number Publication Date
BE1000245A3 true BE1000245A3 (fr) 1988-09-20

Family

ID=25840975

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700113A BE1000245A3 (fr) 1986-02-14 1987-02-12 Nouveaux derives de la purine, leur preparation et leur utilisation comme medicaments.

Country Status (20)

Country Link
US (1) US4849423A (fr)
AT (1) AT389514B (fr)
AU (1) AU590047B2 (fr)
BE (1) BE1000245A3 (fr)
CA (1) CA1285559C (fr)
CH (1) CH668973A5 (fr)
DK (1) DK71187A (fr)
ES (1) ES2004218A6 (fr)
FI (1) FI86728C (fr)
FR (1) FR2596051B1 (fr)
GB (1) GB2186573B (fr)
GR (1) GR870233B (fr)
HU (1) HU198052B (fr)
IL (1) IL81546A (fr)
IT (1) IT1216791B (fr)
LU (1) LU86770A1 (fr)
NL (1) NL8700245A (fr)
NZ (1) NZ219250A (fr)
PH (1) PH23367A (fr)
SE (1) SE468643B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238537A (en) * 1981-09-15 1993-08-24 Dutt William H Extended nip press belt having an interwoven base fabric and an impervious impregnant
US5234551A (en) * 1981-09-24 1993-08-10 Dutt William H Extended nip press belt having an interwoven base fabric and an impervious impregnant
US5057517A (en) * 1987-07-20 1991-10-15 Merck & Co., Inc. Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents
US4885300A (en) * 1988-03-03 1989-12-05 Ortho Pharmaceutical Corporation 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives
US5164390A (en) * 1988-03-03 1992-11-17 Ortho Pharmaceutical Corporation 6-substituted purinyl piperazine derivatives
US5021574A (en) * 1988-03-03 1991-06-04 Ortho Pharmaceutical Corporation 6-substituted purinyl piperazine derivatives
US5215987A (en) * 1990-04-23 1993-06-01 Ortho Pharmaceutical Corporation Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
JP2651043B2 (ja) * 1990-07-10 1997-09-10 麒麟麦酒株式会社 ジフェニルメチルピペラジン誘導体
US5336769A (en) * 1992-02-17 1994-08-09 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
JP5318938B2 (ja) * 2011-06-09 2013-10-16 株式会社アエタスファルマ ジフェニルメチルピペラジン誘導体、及びそれを用いた医薬組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348926A1 (fr) * 1976-04-24 1977-11-18 Wuelfing Johann A Nouveaux derives de l'adenine
EP0052964A1 (fr) * 1980-11-20 1982-06-02 Beecham Group Plc Dérivés d'adénine possédant une activité pharmaceutique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE1620576A1 (de) * 1966-11-25 1970-02-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
GB1165283A (en) * 1967-01-17 1969-09-24 Science Union & Cie New Purine Derivatives and processes for prepararing them
DE2334009A1 (de) * 1973-07-04 1975-01-23 Boehringer Mannheim Gmbh Purin-derivate sowie verfahren zu ihrer herstellung
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
DE3364234D1 (en) * 1982-03-02 1986-07-31 Eisai Co Ltd Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348926A1 (fr) * 1976-04-24 1977-11-18 Wuelfing Johann A Nouveaux derives de l'adenine
EP0052964A1 (fr) * 1980-11-20 1982-06-02 Beecham Group Plc Dérivés d'adénine possédant une activité pharmaceutique

Also Published As

Publication number Publication date
AU590047B2 (en) 1989-10-26
GB2186573A (en) 1987-08-19
CA1285559C (fr) 1991-07-02
IT1216791B (it) 1990-03-14
CH668973A5 (de) 1989-02-15
HU198052B (en) 1989-07-28
GR870233B (en) 1987-06-12
IT8747635A0 (it) 1987-02-12
IL81546A0 (en) 1987-09-16
DK71187D0 (da) 1987-02-12
SE468643B (sv) 1993-02-22
AU6870987A (en) 1987-08-20
ATA29787A (de) 1989-05-15
FI870585L (fi) 1987-08-15
GB2186573B (en) 1989-11-22
SE8700555D0 (sv) 1987-02-12
GB8702937D0 (en) 1987-03-18
FR2596051B1 (fr) 1989-05-26
PH23367A (en) 1989-07-14
HUT45528A (en) 1988-07-28
NL8700245A (nl) 1987-09-01
SE8700555L (sv) 1987-08-15
IL81546A (en) 1990-04-29
LU86770A1 (fr) 1987-09-15
FI870585A0 (fi) 1987-02-12
FI86728B (fi) 1992-06-30
ES2004218A6 (es) 1988-12-16
AT389514B (de) 1989-12-27
FI86728C (fi) 1992-10-12
NZ219250A (en) 1989-10-27
FR2596051A1 (fr) 1987-09-25
DK71187A (da) 1987-08-15
US4849423A (en) 1989-07-18

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: S.A. SANDOZ

Effective date: 19930228