BE2014C063I2 - - Google Patents

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Publication number
BE2014C063I2
BE2014C063I2 BE2014C063C BE2014C063C BE2014C063I2 BE 2014C063 I2 BE2014C063 I2 BE 2014C063I2 BE 2014C063 C BE2014C063 C BE 2014C063C BE 2014C063 C BE2014C063 C BE 2014C063C BE 2014C063 I2 BE2014C063 I2 BE 2014C063I2
Authority
BE
Belgium
Application number
BE2014C063C
Other languages
French (fr)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35242158&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2014C063(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE2014C063I2 publication Critical patent/BE2014C063I2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/452Piperidinium derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
BE2014C063C 2004-04-27 2014-10-02 BE2014C063I2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56562304P 2004-04-27 2004-04-27

Publications (1)

Publication Number Publication Date
BE2014C063I2 true BE2014C063I2 (en) 2024-08-08

Family

ID=35242158

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C063C BE2014C063I2 (en) 2004-04-27 2014-10-02

Country Status (38)

Country Link
US (9) US7498440B2 (en)
EP (3) EP3111936A1 (en)
JP (2) JP5014121B2 (en)
KR (2) KR101037026B1 (en)
CN (2) CN102040602A (en)
AP (1) AP2213A (en)
AR (1) AR050902A1 (en)
AU (1) AU2005237576B2 (en)
BE (1) BE2014C063I2 (en)
BR (1) BRPI0510170B8 (en)
CA (2) CA2755954C (en)
CY (3) CY1113196T1 (en)
DK (2) DK1740177T3 (en)
EA (2) EA021994B1 (en)
EC (1) ECSP066940A (en)
ES (2) ES2392848T4 (en)
FR (1) FR14C0075I2 (en)
HR (2) HRP20120832T1 (en)
HU (2) HUE031304T2 (en)
IL (1) IL178152A (en)
LT (1) LT2570128T (en)
LU (1) LU92565I2 (en)
MA (1) MA28631B1 (en)
MX (1) MXPA06012405A (en)
MY (1) MY144753A (en)
NL (1) NL300694I1 (en)
NO (3) NO338959B1 (en)
NZ (1) NZ549997A (en)
PE (1) PE20060259A1 (en)
PL (2) PL2570128T3 (en)
PT (2) PT1740177E (en)
SG (1) SG186597A1 (en)
SI (2) SI1740177T1 (en)
TW (1) TWI363759B (en)
UA (1) UA95768C2 (en)
UY (1) UY28871A1 (en)
WO (1) WO2005104745A2 (en)
ZA (1) ZA200608565B (en)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR045914A1 (en) * 2003-07-17 2005-11-16 Glaxo Group Ltd TERTIARY ALCOHOLIC COMPOUND OF 8-AZONIABICICLO [3.2.1] OCTOBER, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE THIS LAST
EP1677796A4 (en) * 2003-10-17 2006-12-27 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists field of the invention
PE20050489A1 (en) * 2003-11-04 2005-09-02 Glaxo Group Ltd ANTAGONISTS OF MUSCARINE ACETYLCHOLINE RECEPTORS
WO2005087236A1 (en) * 2004-03-11 2005-09-22 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
US7384946B2 (en) * 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
EP1725238A4 (en) * 2004-03-17 2009-04-01 Glaxo Group Ltd ACETYLCHOLINE M 3 MUSCARINIC RECEPTOR ANTAGONISTS
JP2007531792A (en) * 2004-04-05 2007-11-08 サマリタン,ファーマスーティカルス,インク. Anti-HIV quinuclidine compounds
UY28871A1 (en) 2004-04-27 2005-11-30 Glaxo Group Ltd ANTAGONISTS OF THE MUSCARINIC ACETILCOLINE RECEIVER
EP1747219A4 (en) * 2004-05-13 2010-05-26 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists field of the invention
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
JP2008520579A (en) * 2004-11-15 2008-06-19 グラクソ グループ リミテッド Novel M3 muscarinic acetylcholine receptor antagonist
US20080275079A1 (en) * 2005-08-02 2008-11-06 Glaxo Group Limited M3 Muscarinic Acetylcholine Receptor Antagonists
WO2007022351A2 (en) * 2005-08-18 2007-02-22 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
KR20090003349A (en) 2006-04-20 2009-01-09 글락소 그룹 리미티드 compound
GB0611587D0 (en) 2006-06-12 2006-07-19 Glaxo Group Ltd Novel compounds
PT2046787E (en) 2006-08-01 2011-06-15 Glaxo Group Ltd Pyrazolo[3,4-b]pyridine compounds, and their use as pde4 inhibitors
PE20081889A1 (en) 2007-03-23 2009-03-05 Smithkline Beecham Corp INDOL CARBOXAMIDES AS INHIBITORS OF IKK2
AR070563A1 (en) 2008-02-06 2010-04-21 Glaxo Group Ltd COMPOSITE OF A CONDENSED BICYCLE PIRAZOL-PIRIDIN-AMINA, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A USEFUL MEDICATION FOR THE TREATMENT OF RESPIRATORY DISEASES.
PE20091552A1 (en) 2008-02-06 2009-10-25 Glaxo Group Ltd DUAL PHARMACOFOROS - PDE4 MUSCARINIC ANTAGONISTS
PE20091553A1 (en) 2008-02-06 2009-10-30 Glaxo Group Ltd DUAL PHARMACOFOROS - PDE4 MUSCARINIC ANTAGONISTS
JP5502858B2 (en) 2008-06-05 2014-05-28 グラクソ グループ リミテッド 4-Carboxamide indazole derivatives useful as inhibitors of PI3 kinase
JP5502077B2 (en) 2008-06-05 2014-05-28 グラクソ グループ リミテッド New compounds
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
JP5809985B2 (en) 2009-02-26 2015-11-11 グラクソ グループ リミテッドGlaxo Group Limited A medicament comprising 4-{(1R) -2-[(6- {2-[(2,6-dichlorobenzyl) oxy] ethoxy} hexyl) amino] -1-hydroxyethyl} -2- (hydroxymethyl) phenol Formulation
EP2406255B1 (en) 2009-03-09 2015-04-29 Glaxo Group Limited 4-oxadiazol-2-yl-indazoles as inhibitors of pi3 kinases
WO2010102968A1 (en) 2009-03-10 2010-09-16 Glaxo Group Limited Indole derivatives as ikk2 inhibitors
WO2010106016A1 (en) 2009-03-17 2010-09-23 Glaxo Group Limited Pyrimidine derivatives used as itk inhibitors
AR076435A1 (en) 2009-04-30 2011-06-08 Glaxo Group Ltd COMPOUNDS OF REPLACED INDAZOLS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND PROCESSES TO OBTAIN THEMSELVES
WO2011029896A1 (en) 2009-09-11 2011-03-17 Glaxo Group Limited Methods of preparation of muscarinic acetylcholine receptor antagonists
GB0921075D0 (en) * 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
JP2013512880A (en) 2009-12-03 2013-04-18 グラクソ グループ リミテッド Indazole derivatives as PI3-kinase inhibitors
JP2013512878A (en) 2009-12-03 2013-04-18 グラクソ グループ リミテッド New compounds
WO2011067365A1 (en) 2009-12-03 2011-06-09 Glaxo Group Limited Benzpyrazole derivatives as inhibitors of p13 kinases
KR101781237B1 (en) * 2010-01-28 2017-09-22 테론 파마슈티칼즈, 인크. 7-azoniabicyclo〔2.2.1〕heptane derivatives, methods of production, and pharmaceutical uses thereof
WO2011110575A1 (en) 2010-03-11 2011-09-15 Glaxo Group Limited Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
UA107499C2 (en) * 2010-06-22 2015-01-12 Chiesi Farm Spa DRY POWDER COMPOSITION CONTAINING ANTIMUSCARIN
RS54286B1 (en) 2010-09-08 2016-02-29 Glaxosmithkline Intellectual Property Development Limited POLYMORPHS AND SALTS N- [5- [4- (5 - {[(2R, 6S) -2,6-DIMETHYL-4-MORPHOLINYL] METHYL} -1,3-OXAZOL-2-yl) -1H-INDAZZOL- 6-IL] -2 (methyloxy) -3-pyridinyl] -methanesulfonamide
WO2012035055A1 (en) 2010-09-17 2012-03-22 Glaxo Group Limited Novel compounds
GB201018124D0 (en) 2010-10-27 2010-12-08 Glaxo Group Ltd Polymorphs and salts
KR20140041700A (en) 2011-06-08 2014-04-04 글락소 그룹 리미티드 Dry powder inhaler compositions comprising umeclidinium
US20140113888A1 (en) 2011-06-08 2014-04-24 Glaxo Group Limited Novel Combination of Therapeutic Agents
US9763965B2 (en) 2012-04-13 2017-09-19 Glaxosmithkline Intellectual Property Development Limited Aggregate particles
RU2502743C1 (en) * 2012-08-03 2013-12-27 Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения и социального развития РФ (ФГБУ "РКНПК" Минздравсоцразвития России) Synthetic antigen having ability to fix autoantibodies to muscarine m2-receptor
WO2014027045A1 (en) 2012-08-15 2014-02-20 Glaxo Group Limited Chemical process
GB201222679D0 (en) 2012-12-17 2013-01-30 Glaxo Group Ltd Pharmaceutical combination products
CN105431432B (en) * 2013-07-13 2018-01-09 北京硕佰医药科技有限责任公司 Quinine class compound, its optical isomer and preparation method thereof and medical usage
EA201690302A1 (en) * 2013-07-30 2016-06-30 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед COMPOSITIONS FOR LOCAL APPLICATION FOR THE TREATMENT OF EXCESS MEANS AND METHODS OF THEIR APPLICATION
JP2016537327A (en) 2013-10-17 2016-12-01 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited PI3K inhibitors for the treatment of respiratory diseases
RU2016112266A (en) 2013-10-17 2017-11-20 Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед PI3K inhibitor for the treatment of respiratory disease
WO2015173701A2 (en) 2014-05-12 2015-11-19 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions for treating infectious diseases
EP3650019B8 (en) 2014-05-28 2023-10-11 GlaxoSmithKline Intellectual Property Development Limited Fluticasone furoate in the treatment of copd
JP6615212B2 (en) * 2014-11-03 2019-12-04 オロン ソシエタ ペル アチオニ Preparation of 1- (2-halogen-ethyl) -4-piperidinecarboxylic acid ethyl ester
KR101613245B1 (en) 2015-04-27 2016-04-18 주식회사 대웅제약 Novel 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same
CN105461710A (en) * 2015-10-23 2016-04-06 安徽德信佳生物医药有限公司 Preparation method of umeclidinium bromide
KR102794286B1 (en) * 2016-01-08 2025-04-09 테론 파마슈티칼즈, 인크. Dry powder inhaler composition of 7-azoniabicyclo[2.2.1]heptane derivative
GB201602527D0 (en) 2016-02-12 2016-03-30 Glaxosmithkline Ip Dev Ltd Chemical compounds
CN107200734B (en) * 2016-03-18 2019-12-24 益方生物科技(上海)有限公司 Quinuclidine derivative and preparation method and application thereof
EP3248970A1 (en) 2016-05-27 2017-11-29 Zentiva K.S. Forms of umeclidinium bromide
JP2019524792A (en) 2016-08-08 2019-09-05 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Compound
PT109740B (en) 2016-11-14 2020-07-30 Hovione Farmaciencia Sa PROCESS FOR THE PREPARATION OF UMECLIDINUM BROMIDE
WO2018163212A1 (en) * 2017-03-08 2018-09-13 Gbr Laboratories Pvt. Ltd A process for the preparation of umeclidinium bromide and intermediates thereof
GB201706102D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
IT201700058796A1 (en) 2017-05-30 2018-11-30 Olon Spa Procedure for the preparation of a new intermediate of synthesis of umeclidinium.
GB201712081D0 (en) 2017-07-27 2017-09-13 Glaxosmithkline Ip Dev Ltd Chemical compounds
JP7432506B2 (en) 2017-10-30 2024-02-16 武田薬品工業株式会社 Environmentally compatible surfactants for inactivating lipid enveloped viruses
CN108558860B (en) * 2018-06-04 2020-12-25 成都伊诺达博医药科技有限公司 Method for synthesizing umeclidinium bromide
WO2020047225A1 (en) 2018-08-30 2020-03-05 Theravance Biopharma R&D Ip, Llc Methods for treating chronic obstructive pulmonary disease
PT115583B (en) 2019-06-17 2022-05-02 Hovione Farm S A CONTINUOUS PROCESS FOR THE PREPARATION OF ANTICHOLINERGIC DRUGS
CN113387923A (en) * 2020-03-13 2021-09-14 诺华股份有限公司 Pharmaceutical compositions of lipoic acid choline ester salts and methods of treatment using the same
BR112022019245A2 (en) 2020-03-26 2022-11-16 Glaxosmithkline Ip Dev Ltd CATHEPSIN INHIBITORS TO PREVENT OR TREAT VIRAL INFECTIONS
CN111484445B (en) * 2020-04-21 2021-05-18 广东莱佛士制药技术有限公司 Method for separating and purifying the intermediate of high-purity umeclidinium bromide
CN115397823B (en) * 2020-04-26 2025-11-11 北京硕佰医药科技有限责任公司 Crystal of M receptor antagonist, preparation method and application thereof
CA3192236A1 (en) 2020-09-10 2022-03-17 Tony Lahoutte Antibody fragment against fap
CN112479983B (en) * 2020-11-25 2022-07-12 江苏豪森药业集团有限公司 Wumei ammonium bromide intermediate and preparation method thereof
PT117440B (en) 2021-09-03 2024-04-26 Hovione Farm S A PROCESS FOR THE PREPARATION OF CHLOROAQUIL SUBSTITUTED CYCLIC AMINES
WO2023203135A1 (en) 2022-04-22 2023-10-26 Precirix N.V. Improved radiolabelled antibody
AU2023264245A1 (en) 2022-05-02 2024-12-19 Precirix N.V. Pre-targeting
WO2024251812A1 (en) 2023-06-07 2024-12-12 Pharmazell Gmbh A process for the preparation of umeclidinium bromide intermediate

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800481A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Tertiary alcohol derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
AT298118B (en) 1967-06-08 1972-04-25 Siemens Ag Method for converting voltages into digital values and device for carrying out the method
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1230087A (en) 1967-08-17 1971-04-28
GB1381872A (en) 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
CY1308A (en) 1979-12-06 1985-12-06 Glaxo Group Ltd Device for dispensing medicaments
ATE23272T1 (en) 1981-07-08 1986-11-15 Draco Ab POWDER INHALER.
GB2169265B (en) 1982-10-08 1987-08-12 Glaxo Group Ltd Pack for medicament
NL192564C (en) 1982-10-08 1997-10-03 Glaxo Group Ltd Device for administering medicaments to patients.
EP0211595B1 (en) 1985-07-30 1991-11-13 Glaxo Group Limited Devices for administering medicaments to patients
IT1204826B (en) 1986-03-04 1989-03-10 Chiesi Farma Spa INHALATION PHARMACEUTICAL COMPOSITIONS
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US5780466A (en) 1995-01-30 1998-07-14 Sanofi Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
AU5790598A (en) 1996-12-02 1998-06-29 Georgetown University Tropane derivatives and method for their synthesis
US6248752B1 (en) 1998-02-27 2001-06-19 Charles Duane Smith Azabicyclooctane compositions and methods for enhancing chemotherapy
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
CN1250545C (en) * 2000-12-28 2006-04-12 阿尔米雷尔普罗迪斯制药有限公司 Novel quinucidine derivatives and pharmaceutical compositions containing such derivatives
RU2004110717A (en) 2001-10-17 2005-10-20 Юсиби, С.А. (Be) Quinuclidine derivatives, methods for their preparation and their use as both M2- and / or M3-muscarinic receptors
US6951868B2 (en) * 2001-11-09 2005-10-04 Pfizer Inc. Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
JP4505227B2 (en) * 2001-12-20 2010-07-21 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 1-Alkyl-1-azoniabicyclo [2.2.2] octane carbamate derivatives and their use as muscarinic receptor antagonists
US6696462B2 (en) * 2002-01-31 2004-02-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions
ES2206021B1 (en) 2002-04-16 2005-08-01 Almirall Prodesfarma, S.A. NEW DERIVATIVES OF PIRROLIDINIO.
ES2204295B1 (en) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. NEW DERIVATIVES OF QUINUCLIDINE-AMIDE.
AR040779A1 (en) 2002-08-06 2005-04-20 Glaxo Group Ltd TIAZOL COMPOUND ANILINATES ITS USE TO PREPARE A PHARMACEUTICAL FORMULATION SUCH RECENT FORMULATION CONTAINING IT AND DEVICE ADAPTED FOR THE INTRANASAL ADMINISTRATION OF THE FORMULATION
EP1613307A4 (en) 2003-04-07 2008-03-12 Glaxo Group Ltd M sb 3 /sb muscarinic acetylcholine receptor antagonists
UY28417A1 (en) 2003-07-17 2005-02-28 Glaxo Group Ltd ANTAGONISTS OF ACETILCOLINE MUSCARINIC RECEPTORS
AR048573A1 (en) 2003-07-17 2006-05-10 Glaxo Group Ltd COMPOSITE OF 8-AZONIABICICLO [3.2.1] OCTANO REPLACED IN POSITION 3, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE THIS LAST
AR045914A1 (en) * 2003-07-17 2005-11-16 Glaxo Group Ltd TERTIARY ALCOHOLIC COMPOUND OF 8-AZONIABICICLO [3.2.1] OCTOBER, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE THIS LAST
SI1677795T1 (en) 2003-10-14 2011-04-29 Glaxo Group Ltd Muscarinic acetycholine receptor antagonists
EP1677796A4 (en) 2003-10-17 2006-12-27 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists field of the invention
PE20050489A1 (en) 2003-11-04 2005-09-02 Glaxo Group Ltd ANTAGONISTS OF MUSCARINE ACETYLCHOLINE RECEPTORS
ES2329586T3 (en) 2003-11-21 2009-11-27 Theravance, Inc. COMPOUNDS THAT HAVE AGONIST ACTIVITY OF THE BETA2 ADRENERGIC RECEIVER AND ANTAGONIST OF THE MUSCARINE RECEIVER.
PE20050897A1 (en) 2003-12-03 2005-11-06 Glaxo Group Ltd NEW ANTAGONISTS OF ACETYLCHOLIN MUSCARINE M3 RECEPTOR
TW200530226A (en) 2003-12-03 2005-09-16 Glaxo Group Ltd Novel M3 muscarinic acetylcholine receptor antagonists
TW200534855A (en) 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005087236A1 (en) 2004-03-11 2005-09-22 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
US20070179131A1 (en) 2004-03-11 2007-08-02 Jian Jin Novel M3 Muscarinic Acetylcholine Receptor Antagonists
JP2007529512A (en) 2004-03-17 2007-10-25 グラクソ グループ リミテッド Muscarinic acetylcholine receptor antagonist
EP1725238A4 (en) 2004-03-17 2009-04-01 Glaxo Group Ltd ACETYLCHOLINE M 3 MUSCARINIC RECEPTOR ANTAGONISTS
WO2005094835A1 (en) 2004-03-17 2005-10-13 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
US7384946B2 (en) 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
US20070238751A1 (en) 2004-04-07 2007-10-11 Laine Dramane I Muscarinic Acetylcholine Receptor Antagonists
UY28871A1 (en) 2004-04-27 2005-11-30 Glaxo Group Ltd ANTAGONISTS OF THE MUSCARINIC ACETILCOLINE RECEIVER
EP1747219A4 (en) 2004-05-13 2010-05-26 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists field of the invention
WO2005118594A1 (en) 2004-05-28 2005-12-15 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
JP2008505118A (en) 2004-06-30 2008-02-21 グラクソ グループ リミテッド Muscarinic acetylcholine receptor antagonist
EP1781104A4 (en) 2004-08-05 2008-05-21 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2006017767A2 (en) 2004-08-06 2006-02-16 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
WO2006050239A2 (en) 2004-10-29 2006-05-11 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
EP1827439A4 (en) 2004-11-15 2009-11-18 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
JP2008520579A (en) 2004-11-15 2008-06-19 グラクソ グループ リミテッド Novel M3 muscarinic acetylcholine receptor antagonist
PE20061162A1 (en) 2004-12-06 2006-10-14 Smithkline Beecham Corp COMPOUNDS OLEFINIC DERIVATIVES OF 8-AZONIABICICLO [3.2.1] OCTANES
PE20060826A1 (en) 2004-12-06 2006-10-08 Smithkline Beecham Corp OLEOPHINIC DERIVATIVE OF 8-AZONIABICICLO [3.2.1] OCTANE AND THE PHARMACEUTICAL COMBINATION THAT INCLUDES IT
WO2006065755A2 (en) 2004-12-13 2006-06-22 Glaxo Group Limited Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
WO2006065788A2 (en) 2004-12-13 2006-06-22 Glaxo Group Limited Novel muscarinic acetylcholine receptor antagonists
WO2007018514A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
WO2007018508A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetycholine receptor antagonists
US20080275079A1 (en) 2005-08-02 2008-11-06 Glaxo Group Limited M3 Muscarinic Acetylcholine Receptor Antagonists
US20080234315A1 (en) 2005-08-02 2008-09-25 Jakob Busch-Petersen M3 Muscarinic Acetylcholine Receptor Antagonists
WO2007022351A2 (en) 2005-08-18 2007-02-22 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
GB0921075D0 (en) * 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents

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