BE2017C028I2 - - Google Patents

Info

Publication number
BE2017C028I2
BE2017C028I2 BE2017C028C BE2017C028C BE2017C028I2 BE 2017C028 I2 BE2017C028 I2 BE 2017C028I2 BE 2017C028 C BE2017C028 C BE 2017C028C BE 2017C028 C BE2017C028 C BE 2017C028C BE 2017C028 I2 BE2017C028 I2 BE 2017C028I2
Authority
BE
Belgium
Application number
BE2017C028C
Other languages
French (fr)
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36740357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2017C028(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/042,059 external-priority patent/US7799783B2/en
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of BE2017C028I2 publication Critical patent/BE2017C028I2/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE2017C028C 2005-01-26 2017-08-03 BE2017C028I2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/042,059 US7799783B2 (en) 2005-01-26 2005-01-26 Method of administrating an anticancer drug containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor
JP2005165156 2005-06-06
PCT/JP2006/301097 WO2006080327A1 (en) 2005-01-26 2006-01-25 ANTICANCER DRUG CONTAINING α,α,α-TRIFLUOROTHYMIDINE AND THYMIDINE PHOSPHORYLASE INHIBITOR

Publications (1)

Publication Number Publication Date
BE2017C028I2 true BE2017C028I2 (en) 2025-09-10

Family

ID=36740357

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2017C028C BE2017C028I2 (en) 2005-01-26 2017-08-03

Country Status (20)

Country Link
EP (1) EP1849470B2 (en)
JP (1) JP5576591B2 (en)
KR (1) KR101468216B1 (en)
AU (1) AU2006209547C1 (en)
BE (1) BE2017C028I2 (en)
CA (1) CA2594713A1 (en)
CY (2) CY2017029I2 (en)
DK (1) DK1849470T4 (en)
ES (1) ES2630002T5 (en)
FI (1) FI1849470T4 (en)
FR (1) FR17C1028I2 (en)
HU (2) HUE033306T2 (en)
LT (2) LT1849470T (en)
LU (1) LUC00036I2 (en)
NL (1) NL300889I2 (en)
PL (1) PL1849470T5 (en)
PT (1) PT1849470T (en)
SI (1) SI1849470T2 (en)
TW (1) TWI362265B (en)
WO (1) WO2006080327A1 (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10336400A1 (en) 2003-08-06 2005-03-24 Grünenthal GmbH Anti-abuse dosage form
DE10361596A1 (en) 2003-12-24 2005-09-29 Grünenthal GmbH Process for producing an anti-abuse dosage form
DE102005005446A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Break-resistant dosage forms with sustained release
DE102004032049A1 (en) 2004-07-01 2006-01-19 Grünenthal GmbH Anti-abuse, oral dosage form
JP5576591B2 (en) 2005-01-26 2014-08-20 大鵬薬品工業株式会社 Anticancer agent containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor
DE102005005449A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Process for producing an anti-abuse dosage form
DE102007011485A1 (en) 2007-03-07 2008-09-11 Grünenthal GmbH Dosage form with more difficult abuse
US8536188B2 (en) * 2007-04-25 2013-09-17 Cyclacel Limited Dosing regimens for treatment of proliferative disorders comprising administration of sapacitabine
CA2713128C (en) 2008-01-25 2016-04-05 Gruenenthal Gmbh Pharmaceutical dosage form
AU2009243681B2 (en) 2008-05-09 2013-12-19 Grunenthal Gmbh Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
JP2011520845A (en) * 2008-05-15 2011-07-21 カソリック ユニヴェルシテイト ルーヴェン,ケー.ユー. ルーヴェン アール アンド ディー Treatment with combination of anticancer drugs
KR101738369B1 (en) 2009-07-22 2017-05-22 그뤼넨탈 게엠베하 Hot-melt extruded controlled release dosage form
CN102639118B (en) 2009-07-22 2015-07-29 格吕伦塔尔有限公司 Oxidation-stabilized tamper resistant dosage form
BR112013005194A2 (en) 2010-09-02 2016-05-03 Gruenenthal Gmbh tamper-resistant dosage form comprising inorganic salt
TWI516286B (en) 2010-09-02 2016-01-11 歌林達股份有限公司 Tamper resistant dosage form comprising an anionic polymer
EA201400172A1 (en) 2011-07-29 2014-06-30 Грюненталь Гмбх SUSTAINABLE TO DESTRUCTION TABLET THAT PROVIDES IMMEDIATE RELEASE OF MEDICINES
BR112014001091A2 (en) 2011-07-29 2017-02-14 Gruenenthal Gmbh tamper resistant tablet that provides immediate release of the drug
US9371380B2 (en) 2011-08-16 2016-06-21 Taiho Pharmaceutical Co., Ltd. Antitumor agent and therapeutic effect prediction method for patients with KRAS-mutated colorectal cancer
TWI503122B (en) * 2012-02-15 2015-10-11 Taiho Pharmaceutical Co Ltd Oral administration of pharmaceutical compositions
TWI526210B (en) * 2012-02-15 2016-03-21 Taiho Pharmaceutical Co Ltd Oral pharmaceutical composition
MX356421B (en) 2012-02-28 2018-05-29 Gruenenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer.
EP2838512B1 (en) 2012-04-18 2018-08-22 Grünenthal GmbH Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
WO2013173283A1 (en) 2012-05-16 2013-11-21 Novartis Ag Dosage regimen for a pi-3 kinase inhibitor
JP6002835B2 (en) * 2013-03-27 2016-10-05 大鵬薬品工業株式会社 Antitumor agent containing low-dose irinotecan hydrochloride hydrate
KR101847252B1 (en) * 2013-03-27 2018-04-09 다이호야쿠힌고교 가부시키가이샤 Antitumor agent including irinotecan hydrochloride hydrate
AU2014266278B2 (en) * 2013-05-17 2017-07-13 Taiho Pharmaceutical Co., Ltd. Therapeutic effect prediction method for colorectal cancer patient in whom expression of TK1 protein has increased
EP3003279A1 (en) 2013-05-29 2016-04-13 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
BR112016000194A8 (en) 2013-07-12 2019-12-31 Gruenenthal Gmbh tamper-resistant dosage form containing ethylene vinyl acetate polymer
HRP20230523T1 (en) 2013-09-06 2023-08-04 Taiho Pharmaceutical Co., Ltd. ANTI-TUMOR AGENT AND AGENT FOR IMPROVING ANTI-TUMOR EFFECT
EP3073994A1 (en) 2013-11-26 2016-10-05 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
WO2015173195A1 (en) 2014-05-12 2015-11-19 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
EA201692388A1 (en) 2014-05-26 2017-05-31 Грюненталь Гмбх DOSAGE FORM AS PARTICLE MULTIPLE, PROTECTED AGAINST CALLED DOSE RESET BY ETHANOL
WO2016170097A1 (en) 2015-04-24 2016-10-27 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
JP2018526414A (en) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Protection against oral overdose with abuse-inhibiting immediate release formulations
WO2017119484A1 (en) * 2016-01-08 2017-07-13 大鵬薬品工業株式会社 Anti-tumor agent containing immunomodulator, and anti-tumor effect enhancer
MA43977A (en) 2016-02-05 2018-12-12 Taiho Pharmaceutical Co Ltd METHOD OF TREATMENT OF CANCER PATIENTS WITH SEVERE KIDNEY FAILURE
EP3730935A4 (en) 2017-12-22 2022-02-23 Taiho Pharmaceutical Co., Ltd. METHOD FOR DETECTING ANALOGS DERIVED FROM TRIFLURIDINE AND/OR TIPIRACIL
US10866219B2 (en) 2017-12-22 2020-12-15 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine- and/or tipiracil-related substance
WO2019135405A1 (en) 2018-01-05 2019-07-11 大鵬薬品工業株式会社 Detection method for analog derived from trifluridine
US10816517B2 (en) 2018-01-05 2020-10-27 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine-related substance by high-performance liquid chromatography
WO2026019875A1 (en) * 2024-07-17 2026-01-22 Jnd Therapeutics, Inc. Methods and formulations for treatment of liver cancer using trifluridine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100424934B1 (en) * 1995-03-29 2004-07-27 다이호야쿠힌고교 가부시키가이샤 Uracil derivatives and antitumor effect enhancers and antitumor agents
AU699728B2 (en) * 1996-09-24 1998-12-10 Taiho Pharmaceutical Co., Ltd. Cancerous metastasis inhibitors containing uracil derivatives
JP5576591B2 (en) 2005-01-26 2014-08-20 大鵬薬品工業株式会社 Anticancer agent containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor

Also Published As

Publication number Publication date
RU2394581C2 (en) 2010-07-20
LUC00036I2 (en) 2017-12-01
NL300889I1 (en) 2017-08-14
ES2630002T3 (en) 2017-08-17
ES2630002T5 (en) 2024-09-19
PL1849470T5 (en) 2024-06-10
JP5576591B2 (en) 2014-08-20
SI1849470T1 (en) 2017-10-30
CY2017029I1 (en) 2018-02-14
FR17C1028I1 (en) 2017-09-29
LUC00036I1 (en) 2017-10-02
DK1849470T4 (en) 2024-04-02
CY1119393T1 (en) 2018-02-14
PL1849470T3 (en) 2017-11-30
AU2006209547B2 (en) 2011-05-26
DK1849470T3 (en) 2017-08-14
KR20070104559A (en) 2007-10-26
NL300889I2 (en) 2018-01-16
FI1849470T4 (en) 2024-03-22
TW200637562A (en) 2006-11-01
LTPA2017024I1 (en) 2017-08-10
CY2017029I2 (en) 2018-02-14
HUE033306T2 (en) 2017-11-28
EP1849470B1 (en) 2017-06-21
LTC1849470I2 (en) 2019-10-25
FR17C1028I2 (en) 2018-11-02
EP1849470B2 (en) 2024-03-20
HUS1700032I1 (en) 2017-09-28
PT1849470T (en) 2017-09-22
AU2006209547C1 (en) 2022-04-07
WO2006080327A1 (en) 2006-08-03
TWI362265B (en) 2012-04-21
JPWO2006080327A1 (en) 2008-06-19
EP1849470A4 (en) 2010-12-08
EP1849470A1 (en) 2007-10-31
SI1849470T2 (en) 2024-05-31
CA2594713A1 (en) 2006-08-03
AU2006209547A1 (en) 2006-08-03
KR101468216B1 (en) 2014-12-03
LT1849470T (en) 2017-07-25
RU2007132181A (en) 2009-03-10

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