BE2017C067I2 - - Google Patents

Download PDF

Info

Publication number
BE2017C067I2
BE2017C067I2 BE2017C067C BE2017C067C BE2017C067I2 BE 2017C067 I2 BE2017C067 I2 BE 2017C067I2 BE 2017C067 C BE2017C067 C BE 2017C067C BE 2017C067 C BE2017C067 C BE 2017C067C BE 2017C067 I2 BE2017C067 I2 BE 2017C067I2
Authority
BE
Belgium
Prior art keywords
warm
treatment
allergy
mastocytosis
angioedema
Prior art date
Application number
BE2017C067C
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33539193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2017C067(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BE2017C067I2 publication Critical patent/BE2017C067I2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE2017C067C 2003-06-18 2017-12-19 BE2017C067I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47957503P 2003-06-18 2003-06-18
PCT/EP2004/006562 WO2004112794A2 (fr) 2003-06-18 2004-06-17 Nouvelle utilisation de derives de staurosporine
EP04740016A EP1638574B1 (fr) 2003-06-18 2004-06-17 Nouvelle utilisation de derives de staurosporine

Publications (1)

Publication Number Publication Date
BE2017C067I2 true BE2017C067I2 (fr) 2023-08-09

Family

ID=33539193

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2017C067C BE2017C067I2 (fr) 2003-06-18 2017-12-19

Country Status (23)

Country Link
US (2) US8575146B2 (fr)
EP (1) EP1638574B1 (fr)
JP (2) JP5057780B2 (fr)
CN (2) CN100457111C (fr)
AT (1) ATE464052T1 (fr)
AU (1) AU2004248909B2 (fr)
BE (1) BE2017C067I2 (fr)
BR (1) BRPI0411563B8 (fr)
CA (2) CA2785950A1 (fr)
CY (2) CY1110179T1 (fr)
DE (1) DE602004026578D1 (fr)
DK (1) DK1638574T3 (fr)
ES (1) ES2344700T3 (fr)
FR (1) FR17C1063I2 (fr)
HU (1) HUS000503I2 (fr)
LU (1) LUC00055I9 (fr)
MX (1) MXPA05013722A (fr)
NL (1) NL300917I2 (fr)
PL (1) PL1638574T3 (fr)
PT (1) PT1638574E (fr)
SI (1) SI1638574T1 (fr)
TW (1) TWI324604B (fr)
WO (1) WO2004112794A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
US20060014165A1 (en) * 2003-07-14 2006-01-19 Decode Genetics Ehf. Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association
JP4762150B2 (ja) 2003-11-18 2011-08-31 ノバルティス アーゲー Kitの変異体の阻害剤
WO2005115385A1 (fr) * 2004-05-24 2005-12-08 Ab Science Utilisation d'inhibiteurs de c-kit pour le traitement de l'acne
AU2005274852B2 (en) * 2004-07-19 2011-12-08 The Johns Hopkins University FLT3 inhibitors for immune suppression
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
GB0419159D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
CN101171013A (zh) * 2005-05-02 2008-04-30 诺瓦提斯公司 嘧啶基氨基苯甲酰胺衍生物用于治疗全身性肥大细胞增多症的应用
DE602006013826D1 (de) * 2005-07-20 2010-06-02 Peter Valent Zusammensetzungen zur behandlung von systemischer mastocytose
CA2629478C (fr) * 2005-11-14 2013-10-15 Universitat Zurich Derives de la staurosporine utilisables dans le rhabdomyosarcome alveolaire
WO2009092442A1 (fr) * 2008-01-23 2009-07-30 Universidad De Barcelona Traitement de l'hypertension portale et d'états apparentés par une inhibition combinée des voies de signalisation de vegf et pdgf
EP2637650A2 (fr) * 2010-11-10 2013-09-18 National Jewish Health Procédés de test d'états allergiques
AU2019374142A1 (en) 2018-11-01 2021-05-27 Syros Pharmaceuticals, Inc. Methods of treating cancer in biomarker-identified patients with non-covalent inhibitors of cyclin-dependent kinase 7 (CDK7)
US11325978B2 (en) * 2018-11-06 2022-05-10 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for treating beta-globinopathies
US11839619B2 (en) * 2019-09-16 2023-12-12 The Regents Of The University Of California Methods for treatment of pediatric systemic mastocytosis
KR102805013B1 (ko) * 2022-03-15 2025-05-09 국립해양생물자원관 스트렙토마이세스 속 snc087 균주 또는 이로부터 분리한 스타우로스포린을 유효성분으로 포함하는 비용종 예방 또는 치료용 약학 조성물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639455A (en) * 1984-10-02 1987-01-27 Key Pharmaceuticals, Inc. Means of aiding in the prevention of sudden infant death syndrome
JPH0826037B2 (ja) * 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質k−252の誘導体
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
CA2046801C (fr) * 1990-08-07 2002-02-26 Peter D. Davis Pyrroles substitues
DE69229490T2 (de) * 1991-05-09 2000-02-17 Neurim Pharmaceuticals (1991) Ltd., Tel Aviv Melatonin enthaltende Arzneimittel
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
US6184217B1 (en) * 1996-06-25 2001-02-06 Cephalon, Inc. Use of K-252a derivative
US6093740A (en) * 1997-04-30 2000-07-25 Eli Lilly And Company Therapeutic treatment for skin disorders
WO1999062537A1 (fr) 1998-06-04 1999-12-09 The Rockefeller University Procedes et agents permettant la modulation de la reponse immunitaire et de l'inflammation par modulation des proteines membranaires des monocytes et des cellules dendritiques
GB9903547D0 (en) * 1999-02-16 1999-04-07 Novartis Ag Organic compounds
CA2431187A1 (fr) 2000-12-08 2002-06-13 Ortho-Mcneil Pharmaceutical, Inc. Composes macro-heterocyliques utilises comme inhibiteurs de kinase
GB0108606D0 (en) 2001-04-05 2001-05-23 Novartis Ag Organic compounds
DE60227709D1 (de) * 2001-06-29 2008-08-28 Ab Science Die verwendung von c-kithemmern zur behandlung von autoimmunerkrankungen
US20030091974A1 (en) * 2001-06-29 2003-05-15 Alain Moussy Method for screening compounds capable of depleting mast cells
CN101703509A (zh) * 2001-10-30 2010-05-12 诺瓦提斯公司 作为flt3受体酪氨酸激酶活性抑制剂的星形孢菌素衍生物
US6998391B2 (en) 2002-02-07 2006-02-14 Supergen.Inc. Method for treating diseases associated with abnormal kinase activity
EP1645286A1 (fr) * 2003-04-18 2006-04-12 Kyowa Hakko Kogyo Co., Ltd. Medicament pour la regeneration des nerfs
US20070037882A1 (en) * 2003-04-22 2007-02-15 Astellas Pharma Inc. Remedy for cerebral neurodegenerative diseases using ppar agonist
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
JP4762150B2 (ja) 2003-11-18 2011-08-31 ノバルティス アーゲー Kitの変異体の阻害剤

Also Published As

Publication number Publication date
CN1805749A (zh) 2006-07-19
FR17C1063I2 (fr) 2019-05-03
CY2017048I2 (el) 2018-09-05
JP2012144572A (ja) 2012-08-02
US8575146B2 (en) 2013-11-05
HUS1700053I1 (hu) 2018-01-29
JP2006527727A (ja) 2006-12-07
BRPI0411563B8 (pt) 2021-05-25
JP5057780B2 (ja) 2012-10-24
PT1638574E (pt) 2010-07-14
WO2004112794A2 (fr) 2004-12-29
EP1638574B1 (fr) 2010-04-14
CA2527703C (fr) 2012-10-23
LUC00055I1 (fr) 2017-12-14
WO2004112794A3 (fr) 2005-06-16
LUC00055I2 (fr) 2018-02-21
CY1110179T1 (el) 2015-01-14
FR17C1063I1 (fr) 2018-02-16
TW200512213A (en) 2005-04-01
SI1638574T1 (sl) 2010-08-31
EP1638574A2 (fr) 2006-03-29
AU2004248909B2 (en) 2008-05-08
BRPI0411563B1 (pt) 2019-09-24
HK1095519A1 (zh) 2007-05-11
CN101164539A (zh) 2008-04-23
ATE464052T1 (de) 2010-04-15
NL300917I2 (nl) 2018-01-09
CY2017048I1 (el) 2018-09-05
DK1638574T3 (da) 2010-08-02
CN100457111C (zh) 2009-02-04
TWI324604B (en) 2010-05-11
LUC00055I9 (fr) 2022-11-09
AU2004248909A1 (en) 2004-12-29
PL1638574T3 (pl) 2010-09-30
BRPI0411563A (pt) 2006-08-01
HUS000503I2 (hu) 2021-03-29
CA2785950A1 (fr) 2004-12-29
US20130289018A1 (en) 2013-10-31
ES2344700T3 (es) 2010-09-03
MXPA05013722A (es) 2006-03-08
CA2527703A1 (fr) 2004-12-29
US20070299049A1 (en) 2007-12-27
NL300917I1 (nl) 2017-12-12
DE602004026578D1 (de) 2010-05-27

Similar Documents

Publication Publication Date Title
FR17C1063I1 (fr)
DK1611088T3 (da) Hydroxymater som terapeutiske midler
EA200971053A1 (ru) Способы лечения кожных язв
SG170101A1 (en) 2-pyrazinone derivatives for the treatment of disease or condition in which inhibition of neutrophil elastase activity is beneficial.
EA201390353A1 (ru) Производное пиразолохинолина
WO2000064441A3 (fr) Medicament
MX2008013836A (es) Derivados de 2-piridona para el tratamiento de enfermedades o condiciones en las cuales es benefica la inhibicion de la actividad de elastasa de neutrofilos.
ATE520668T1 (de) Sigmarezeptor-inhibitoren
PL1656348T3 (pl) Pochodne acetylenu jako inhibitory deacetylazy histonowej
TNSN04203A1 (en) Benzoxazinone-derived compounds, their preparation and use as medicaments
WO2008070010A3 (fr) Rétablissement après une attaque
MXPA06014182A (es) Nucleosidos de 3-??-d-ribofuranosiltiazolo[4,5-d]piridimina y usos de los mismos.
GB2427405A (en) Novel hydroxamates as therapeutic agents
WO2000076500A8 (fr) Compound for use as a medicament for treatment of disorders involving bronchocontraction
TH401002069A (th) การใช้แบบใหม่ของอนุพันธ์สเทาโรสพอรีน
RU2006126471A (ru) Способ лечения воспалительных заболеваний слюнных желез
SE0103539D0 (sv) New Use