BE2018C032I2 - - Google Patents
Info
- Publication number
- BE2018C032I2 BE2018C032I2 BE2018C032C BE2018C032C BE2018C032I2 BE 2018C032 I2 BE2018C032 I2 BE 2018C032I2 BE 2018C032 C BE2018C032 C BE 2018C032C BE 2018C032 C BE2018C032 C BE 2018C032C BE 2018C032 I2 BE2018C032 I2 BE 2018C032I2
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/14—Compounds containing azido groups with azido groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6995697P | 1997-12-17 | 1997-12-17 | |
| US8525298P | 1998-05-13 | 1998-05-13 | |
| PCT/US1998/026871 WO1999033781A1 (en) | 1997-12-17 | 1998-12-17 | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE2018C032I2 true BE2018C032I2 (en) | 2018-10-15 |
Family
ID=26750600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2018C032C BE2018C032I2 (en) | 1997-12-17 | 2018-09-04 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6562861B1 (en) |
| EP (1) | EP1040094B9 (en) |
| JP (3) | JP4102022B2 (en) |
| KR (1) | KR20010024743A (en) |
| CN (1) | CN1282316A (en) |
| AR (1) | AR016162A1 (en) |
| AT (1) | ATE425955T1 (en) |
| AU (1) | AU2200199A (en) |
| BE (1) | BE2018C032I2 (en) |
| BR (1) | BR9813480A (en) |
| CA (1) | CA2315262C (en) |
| CY (2) | CY1109153T1 (en) |
| DE (1) | DE69840674D1 (en) |
| DK (1) | DK1040094T3 (en) |
| ES (1) | ES2324746T3 (en) |
| FR (1) | FR18C1037I2 (en) |
| HU (1) | HUP0100142A3 (en) |
| IL (1) | IL136812A0 (en) |
| LT (1) | LTC1040094I2 (en) |
| NL (1) | NL300952I2 (en) |
| NO (1) | NO20003084L (en) |
| PL (1) | PL196674B1 (en) |
| PT (1) | PT1040094E (en) |
| RO (1) | RO121815B1 (en) |
| SI (1) | SI1040094T1 (en) |
| SK (1) | SK8712000A3 (en) |
| WO (1) | WO1999033781A1 (en) |
| ZA (1) | ZA9811595B (en) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL330407A1 (en) | 1996-06-14 | 1999-05-10 | Biocryst Pharmaceuticals | Substituted cyclopentane compounds useful as neuraminidaze inhibitors |
| SI1040094T1 (en) * | 1997-12-17 | 2009-10-31 | Biocryst Pharm Inc | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
| CA2329660A1 (en) * | 1998-04-23 | 1999-10-28 | Abbott Laboratories | Inhibitors of neuraminidases |
| WO2000028328A1 (en) | 1998-11-05 | 2000-05-18 | Biocryst Pharmaceuticals, Inc. | New cyclopentane and cyclopentene compounds and use for detecting influenza virus |
| US6762316B1 (en) * | 1999-06-28 | 2004-07-13 | Biocryst Pharmaceuticals, Inc. | Preparation of substituted cyclopentane and cyclopentene compounds and certain intermediates |
| AR024600A1 (en) * | 1999-06-28 | 2002-10-16 | Biocryst Pharm Inc | PREPARATION OF CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS SUBSTITUTED AND CERTAIN INTERMEDIARIES |
| KR20020013937A (en) * | 1999-06-28 | 2002-02-21 | 다우 케네드 제이. | Process for preparing (-)-(1s,4r) n-protected 4-amino-2-cyclopentene-1-carboxylate esters |
| WO2001000571A1 (en) * | 1999-06-28 | 2001-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof |
| US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| US6627396B1 (en) | 1999-10-28 | 2003-09-30 | The Regents Of The University Of California | Influenza sensor |
| WO2001062242A1 (en) * | 2000-02-24 | 2001-08-30 | Biocryst Pharmaceuticals, Inc. | Prodrugs of substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| JP2003525291A (en) * | 2000-03-01 | 2003-08-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 2,4-disubstituted thiazolyl derivatives |
| WO2001080892A1 (en) * | 2000-04-25 | 2001-11-01 | Sankyo Company, Limited | Preventives for influenza |
| GB0015324D0 (en) * | 2000-06-22 | 2000-08-16 | Biota Scient Management | Medicaments |
| AUPR001000A0 (en) | 2000-09-08 | 2000-10-05 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| US7038059B2 (en) | 2000-10-18 | 2006-05-02 | Kuraray Co., Ltd. | Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates |
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| EP1831235B1 (en) | 2004-12-16 | 2013-02-20 | The Regents of The University of California | Lung-targeted drugs |
| WO2007087056A2 (en) * | 2006-01-13 | 2007-08-02 | Scolr Pharma, Inc. | Peramivir derivative for oral administration |
| EA025483B1 (en) * | 2006-02-13 | 2016-12-30 | Байокрист Фармасьютикалз, Инк. | Intravenous method for treating a seasonal influenza |
| CN101420948A (en) | 2006-02-13 | 2009-04-29 | 拜奥克里斯特制药公司 | Intravenous antiviral treatment |
| JP2009533428A (en) * | 2006-04-12 | 2009-09-17 | バイオクライスト ファーマシューティカルズ， インコーポレイテッド | Intramuscular antiviral treatment |
| US20070244193A1 (en) * | 2006-04-12 | 2007-10-18 | Babu Yarlagadda S | Intramuscular antiviral treatments |
| CN100432047C (en) * | 2006-07-03 | 2008-11-12 | 华南农业大学 | A kind of synthetic method of anti-influenza and avian influenza virus drug Peramivir |
| US8227425B2 (en) | 2007-01-23 | 2012-07-24 | Therapicon Srl | Antiviral compounds |
| US20080194801A1 (en) * | 2007-02-14 | 2008-08-14 | Swanson Basil I | Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses |
| KR101925902B1 (en) | 2007-08-02 | 2018-12-06 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | Process for the synthesis of e1 activating enzyme inhibitors |
| CN101367750B (en) | 2007-08-14 | 2012-05-23 | 中国人民解放军军事医学科学院毒物药物研究所 | (1S,2S,3S,4R)-3-[(1S)-1-acet-ammonia-2-ethyl-butyl]-4- guanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid aqua compound and medical uses thereof |
| AU2014200052B2 (en) * | 2007-11-05 | 2016-01-07 | Ala Wai Pharma, Inc. | Formulations for enhanced bioavailability of orally administered polar agents |
| CN102014878B (en) | 2007-11-05 | 2013-10-23 | 夏威夷大学 | Enhanced bioavailability formulations for oral administration of polar pharmaceutical agents |
| CN101538228B (en) * | 2008-03-21 | 2012-05-30 | 北京普世康医药技术有限公司 | Method for synthesizing medical compound peramivir for resisting influenza viruses and avian influenza viruses |
| CN101486664B (en) * | 2008-12-31 | 2013-09-04 | 北京大学深圳研究生院 | Polysubstituted five membered ring small molecular compound used as influenza virus neuraminidase inhibitor |
| NZ610978A (en) | 2009-05-15 | 2014-11-28 | Redx Pharma Ltd | Redox drug derivatives |
| IT1396620B1 (en) | 2009-11-25 | 2012-12-14 | Therapicon Srl | CHEMICAL ANALOGUES |
| EP2576553A4 (en) | 2010-05-27 | 2013-11-20 | Reddys Lab Ltd Dr | Highly selective asymmetric hydroformylation of (1s,4r) or (1r,4s)-2-azabicyclo[2.2.1]hept-5-en-3- one (+) or (-)-lactam |
| CN102584637B (en) * | 2011-01-17 | 2014-07-09 | 天津药物研究院 | Peramivir hydrate crystal, preparation method, medical compound and usage thereof |
| CN102603577A (en) * | 2011-01-19 | 2012-07-25 | 董慧珍 | Derivatives of anti-influenza and anti-avian influenza medicament and application thereof |
| CN103827082B (en) * | 2011-04-29 | 2016-01-20 | 上海泓博智源医药技术有限公司 | A kind of novel process preparing Peramivir and intermediate thereof |
| CN102757365B (en) * | 2011-04-29 | 2013-10-30 | 上海泓博智源医药技术有限公司 | Method for preparing peramivir key intermediate |
| CN102964267B (en) * | 2011-09-01 | 2015-06-10 | 中山大学 | Cyclohexene compound having influenza virus neuraminidase inhibition activity, preparation method and application |
| CN102863359B (en) * | 2012-05-16 | 2014-05-07 | 常州制药厂有限公司 | Synthesis method of anti-flu medicine |
| CN102702033A (en) * | 2012-06-11 | 2012-10-03 | 天津泰普药品科技发展有限公司 | Amorphous peramivir, preparation method thereof and medicinal composition |
| WO2014068265A1 (en) | 2012-10-29 | 2014-05-08 | Cipla Limited | Antiviral phosphonate analogues and process for preparation thereof |
| CN107056838A (en) | 2013-03-15 | 2017-08-18 | 加利福尼亚大学董事会 | Acyclic nucleoside phosphonate diester |
| AU2014265483B2 (en) | 2013-05-14 | 2018-08-02 | Biocryst Pharmaceuticals, Inc. | Anti-influenza compositions and methods |
| CN105294589B (en) * | 2014-06-18 | 2017-06-30 | 朱靖华 | A kind of antiviral drugs and preparation method thereof |
| SG11201701957XA (en) | 2014-09-15 | 2017-04-27 | Univ California | Nucleotide analogs |
| CN104387288B (en) * | 2014-11-25 | 2016-04-20 | 广东东阳光药业有限公司 | As the compound of neuraminidase inhibitor and the application in medicine thereof |
| CN104496839B (en) * | 2014-12-03 | 2016-04-20 | 广东东阳光药业有限公司 | Substituted cyclobutane neuraminidase inhibitors and methods and uses thereof |
| CN104496838B (en) * | 2014-12-03 | 2016-04-20 | 广东东阳光药业有限公司 | Substituted ring butanes neuraminidase inhibitor and using method thereof and purposes |
| CN104496857B (en) * | 2014-12-10 | 2016-10-12 | 广东东阳光药业有限公司 | As the compound of neuraminidase inhibitor and the application in medicine thereof |
| CN105198827A (en) * | 2015-04-13 | 2015-12-30 | 广州南新制药有限公司 | Synthetic method of peramivir intermediate |
| CN108026049B (en) | 2015-08-10 | 2021-08-31 | 阿尔泽恩股份有限公司 | Compositions and methods for treating and preventing neurodegenerative disorders |
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1998
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- 1998-12-17 US US09/555,131 patent/US6562861B1/en not_active Expired - Lifetime
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- 1998-12-17 DK DK98966003T patent/DK1040094T3/en active
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2000
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2008
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2009
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2011
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2018
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