BE731398A - Procédé de préparation de l'adriamycine et de l'adriamycinone - Google Patents
Procédé de préparation de l'adriamycine et de l'adriamycinoneInfo
- Publication number
- BE731398A BE731398A BE731398DA BE731398A BE 731398 A BE731398 A BE 731398A BE 731398D A BE731398D A BE 731398DA BE 731398 A BE731398 A BE 731398A
- Authority
- BE
- Belgium
- Prior art keywords
- adriamycinone
- adriamycin
- preparing
- preparing adriamycin
- Prior art date
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 2
- IBZGBXXTIGCACK-CWKPULSASA-N Adriamycinone Chemical compound C1[C@@](O)(C(=O)CO)C[C@H](O)C2=C1C(O)=C1C(=O)C(C=CC=C3OC)=C3C(=O)C1=C2O IBZGBXXTIGCACK-CWKPULSASA-N 0.000 title 1
- 229940009456 adriamycin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1515968 | 1968-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE731398A true BE731398A (fr) | 1969-10-13 |
Family
ID=11146828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE731398D BE731398A (fr) | 1968-04-12 | 1969-04-11 | Procédé de préparation de l'adriamycine et de l'adriamycinone |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT283597B (de) |
| BE (1) | BE731398A (de) |
| CH (1) | CH518250A (de) |
| DE (1) | DE1917874C3 (de) |
| DK (1) | DK126987B (de) |
| ES (1) | ES365907A1 (de) |
| FR (1) | FR2007443A1 (de) |
| GB (1) | GB1217133A (de) |
| IL (1) | IL31966A (de) |
| NL (1) | NL145536B (de) |
| NO (1) | NO133271C (de) |
| SE (1) | SE359293B (de) |
| YU (1) | YU34389B (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2160716A1 (en) * | 1971-11-23 | 1973-07-06 | Rhone Poulenc Sa | Antibiotics duborimycin and 27706rp - by reduction of daunorubicin and adriamycin |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2135221A1 (en) * | 1971-05-04 | 1972-12-15 | Farmaceutici Italia | Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid |
| US4201773A (en) * | 1978-07-26 | 1980-05-06 | The United States Of America As Represented By The Department Of Health, Education And Welfare | 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone |
| US4348388A (en) * | 1980-04-02 | 1982-09-07 | G.D. Searle & Co. | 11-Amino-11-deoxydaunorubicin and analogs |
| GB2125030B (en) * | 1982-08-13 | 1986-11-26 | Erba Farmitalia | Naphthacenequinone synthesis |
| WO1986000073A1 (en) * | 1984-06-14 | 1986-01-03 | BIOGAL Gyógyszergyár | Process for preparing adriamycine and halide salts thereof |
| GB2169285A (en) * | 1985-01-05 | 1986-07-09 | Erba Farmitalia | 4'-Deoxydoxorubicin-14-esters |
| GB2169286A (en) * | 1985-01-05 | 1986-07-09 | Erba Farmitalia | 4'-Deoxy-4'-halodoxorubicin-14-esters |
| GB2169284A (en) * | 1985-01-05 | 1986-07-09 | Erba Farmitalia | 4'-Epidoxorubicin-14-esters |
| JP3112342B2 (ja) * | 1992-06-10 | 2000-11-27 | 協和醗酵工業株式会社 | 新規化合物ｕｃｅ６ |
| EP0648503B1 (de) * | 1993-09-22 | 2000-07-26 | Hoechst Aktiengesellschaft | Pro-Prodrugs, ihre Herstellung und Anwendung |
| GB9416007D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Anthracyclinone derivatives |
| US9670242B2 (en) * | 2012-03-06 | 2017-06-06 | Tianjin Hemay Oncology Pharmaceutical Co., Ltd. | Tetracyclic anthraquinone derivatives |
-
1969
- 1969-03-28 NL NL696904844A patent/NL145536B/xx not_active IP Right Cessation
- 1969-04-07 IL IL31966A patent/IL31966A/en unknown
- 1969-04-07 YU YU858/69A patent/YU34389B/xx unknown
- 1969-04-08 DE DE1917874A patent/DE1917874C3/de not_active Expired
- 1969-04-10 NO NO1464/69A patent/NO133271C/no unknown
- 1969-04-10 AT AT347269A patent/AT283597B/de not_active IP Right Cessation
- 1969-04-10 FR FR6911030A patent/FR2007443A1/fr active Pending
- 1969-04-10 SE SE05048/69A patent/SE359293B/xx unknown
- 1969-04-10 DK DK197469AA patent/DK126987B/da unknown
- 1969-04-11 BE BE731398D patent/BE731398A/xx not_active IP Right Cessation
- 1969-04-11 CH CH557169A patent/CH518250A/de not_active IP Right Cessation
- 1969-04-11 ES ES365907A patent/ES365907A1/es not_active Expired
- 1969-04-11 GB GB08719/69A patent/GB1217133A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2160716A1 (en) * | 1971-11-23 | 1973-07-06 | Rhone Poulenc Sa | Antibiotics duborimycin and 27706rp - by reduction of daunorubicin and adriamycin |
Also Published As
| Publication number | Publication date |
|---|---|
| CH518250A (de) | 1972-01-31 |
| DK126987B (da) | 1973-09-10 |
| IL31966A (en) | 1972-11-28 |
| GB1217133A (en) | 1970-12-31 |
| FR2007443A1 (de) | 1970-01-09 |
| IL31966A0 (en) | 1969-06-25 |
| DE1917874A1 (de) | 1969-11-06 |
| NO133271B (de) | 1975-12-29 |
| SE359293B (de) | 1973-08-27 |
| NO133271C (de) | 1976-04-07 |
| NL145536B (nl) | 1975-04-15 |
| ES365907A1 (es) | 1971-03-16 |
| YU34389B (en) | 1979-07-10 |
| DE1917874B2 (de) | 1980-02-07 |
| YU85869A (en) | 1978-12-31 |
| DE1917874C3 (de) | 1980-10-02 |
| NL6904844A (de) | 1969-10-14 |
| AT283597B (de) | 1970-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: FARMITALIA CARLO ERBA S.R.L. Effective date: 19890411 |
|
| CN | Change of patent owner's name |
Owner name: *FARMITALIA CARLO ERBA S.R.L. Effective date: 19880627 |