BE747492A - Nouveaux steroides physiologiquement actifs, et leur procede defabrication - Google Patents

Nouveaux steroides physiologiquement actifs, et leur procede defabrication

Info

Publication number
BE747492A
BE747492A BE747492DA BE747492A BE 747492 A BE747492 A BE 747492A BE 747492D A BE747492D A BE 747492DA BE 747492 A BE747492 A BE 747492A
Authority
BE
Belgium
Prior art keywords
manufacturing process
physiologically active
active steroids
new physiologically
new
Prior art date
Application number
Other languages
English (en)
Inventor
J C Babcock
J A Campbell
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE747492A publication Critical patent/BE747492A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
BE747492D 1969-03-17 1970-03-17 Nouveaux steroides physiologiquement actifs, et leur procede defabrication BE747492A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00807929A US3833622A (en) 1969-03-17 1969-03-17 Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds

Publications (1)

Publication Number Publication Date
BE747492A true BE747492A (fr) 1970-09-17

Family

ID=25197461

Family Applications (1)

Application Number Title Priority Date Filing Date
BE747492D BE747492A (fr) 1969-03-17 1970-03-17 Nouveaux steroides physiologiquement actifs, et leur procede defabrication

Country Status (10)

Country Link
US (1) US3833622A (fr)
JP (1) JPS4934980B1 (fr)
BE (1) BE747492A (fr)
CA (1) CA968789A (fr)
CH (1) CH528500A (fr)
DE (1) DE2012167C2 (fr)
FR (1) FR2035000B1 (fr)
GB (1) GB1286761A (fr)
IL (1) IL33860A (fr)
NL (1) NL7003686A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571369A1 (fr) * 1984-10-04 1986-04-11 Wisconsin Alumni Res Found Derives de la vitamine d et precurseurs de ceux-ci et compositions pharmaceutiques en contenant

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012509A (en) * 1974-06-10 1977-03-15 The Upjohn Company Composition of matter and process
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US3906014A (en) * 1974-06-17 1975-09-16 Wisconsin Alumni Res Found 3-Deoxy-1{60 -hydroxycholecalciferol
US4001096A (en) * 1975-02-21 1977-01-04 The Upjohn Company Process for preparing 25-hydroxycholecalciferol intermediates
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
USRE30538E (en) * 1977-03-07 1981-03-03 Wisconsin Alumni Research Foundation 3-Deoxy-1α-hydroxycholecalciferol
US4217288A (en) * 1977-03-24 1980-08-12 Wisconsin Alumni Research Foundation Anti-vitamin D compounds
US4119647A (en) * 1977-04-11 1978-10-10 Hoffmann-La Roche Inc. 25-Hydroxycholecalciferol-23,24-3 H and process for the preparation thereof
JPS6039278B2 (ja) * 1977-05-23 1985-09-05 中外製薬株式会社 ステロイド誘導体
US4183852A (en) * 1977-07-18 1980-01-15 Kaiser Emil T Process for preparing 25-hydroxycholesterol
JPS5822479B2 (ja) * 1977-09-07 1983-05-09 帝人株式会社 １α−ヒドロキシ−２４−オキソ−ビタミンＤ↓３およびその製造法
US4188345A (en) * 1978-07-26 1980-02-12 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4269777A (en) * 1979-05-21 1981-05-26 Wisconsin Alumni Research Foundation Isotopically labeled vitamin D derivatives and processes for preparing same
FR2457282A1 (fr) * 1979-05-23 1980-12-19 Roussel Uclaf Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
IL60270A0 (en) * 1979-06-14 1980-09-16 Diamond Shamrock Corp Preparation of 25-ydroxycholesterol
US4252797A (en) * 1979-07-19 1981-02-24 Walter Rosenthal Corticosteroid calcium compositions and treatment of rheumatic diseases therewith
US4260804A (en) * 1980-02-20 1981-04-07 Wisconsin Alumni Research Foundation Processes for preparing calcitroic acid and esters thereof
US5043170A (en) * 1989-02-14 1991-08-27 Hoffmann-La Roche Inc. Animal feed composition containing a vitamin D metabolite
AU666529B2 (en) * 1992-04-24 1996-02-15 Wisconsin Alumni Research Foundation Method of treating osteoporosis with 1 alpha, 24 (R)-dihydroxy-22 (E)-dehydro-vitamin D3
KR960013798B1 (ko) * 1992-04-24 1996-10-10 재단법인 한국전자통신연구소 평면 도파로형 공간 스위치
US5194431A (en) 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
KR100364941B1 (ko) 1994-04-15 2003-02-19 파마시아 앤드 업존 캄파니 1-[5-메탄설폰아미도인돌릴-2-카보닐]-4-[3-(1-메틸에틸아미노)-2-피리디닐]피페라진의신규한결정형태
US6432936B1 (en) 1999-01-20 2002-08-13 Wisconsin Alumni Research Foundation Crystalline 1α-hydroxyvitamin D2 and method of purification thereof
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
DK3095447T3 (da) 2006-02-03 2022-01-31 Opko Renal Llc Behandling af vitamin d-insufficiens og -mangel med 25-hydroxyvitamin d2 og 25-hydroxyvitamin d3
DK2679228T3 (en) 2006-06-21 2018-06-06 Opko Ireland Global Holdings Ltd Therapy with a vitamin D refill and a vitamin D hormone replacement
ES2403107T3 (es) 2007-04-25 2013-05-14 Cytochroma Inc. Método de tratamiento de insuficiencia y deficiencia de vitamina D
EP3225243B1 (fr) 2007-04-25 2025-09-03 Opko Renal, LLC Procédé sûr et efficace de traitement et de prévention de l'hyperparathyroïdisme secondaire dans une maladie rénale chronique
PL3542792T3 (pl) 2007-04-25 2023-11-20 Eirgen Pharma Ltd. 25-hydroksywitamina d o kontrolowanym uwalnianiu
US8962239B2 (en) 2008-04-02 2015-02-24 Opko Renal, Llc Methods useful for vitamin D deficiency and related disorders
SMT202000167T1 (it) 2010-03-29 2020-05-08 Opko Ireland Global Holdings Ltd Metodi e composizioni per la riduzione dei livelli paratiroidei
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
SG11201808227YA (en) 2016-03-28 2018-10-30 Opko Ireland Global Holdings Limited Methods of vitamin d treatment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1052283B (it) * 1968-07-01 1981-06-20 Wisconsin Alumni Res Found Processo per preparare composti del calciferolo e relativi composti

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571369A1 (fr) * 1984-10-04 1986-04-11 Wisconsin Alumni Res Found Derives de la vitamine d et precurseurs de ceux-ci et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
CH528500A (de) 1972-09-30
IL33860A0 (en) 1970-04-20
JPS4934980B1 (fr) 1974-09-19
DE2012167A1 (de) 1970-10-01
FR2035000A1 (fr) 1970-12-18
IL33860A (en) 1973-10-25
DE2012167C2 (de) 1982-09-23
CA968789A (en) 1975-06-03
NL7003686A (fr) 1970-09-21
FR2035000B1 (fr) 1974-01-11
US3833622A (en) 1974-09-03
GB1286761A (en) 1972-08-23

Similar Documents

Publication Publication Date Title
BE747492A (fr) Nouveaux steroides physiologiquement actifs, et leur procede defabrication
BE799727A (fr) Nouveaux steroides physiologiquement actifs, et procede pour leur preparation.
BE772309A (fr) Nouveaux alpha, epsilon-di-s-triazinyl-perfluoropolyoxaalcane et leur procede de preparation
BE752512A (fr) Nouvelles polyaryl-ether-sulfones et leur procede de preparation
BE748017R (fr) Nouveaux composes du bis-stilbene, leur procede de preparation et leur
BE754111A (fr) Nouveaux 7alpha- et 7beta-methyl-3alpha,5alpha- cycloandrostanes et composes analogues 19-nor et leur procede de preparation
BE746737A (fr) Nouveaux composes azoliques, leur procede de preparation et leur emplo
BE746738A (fr) Nouveaux composes azoliques, leur procede de preparation et leur emplo
BE772739A (fr) Nouveaux 17-chlorosteroides, leur procede de preparation et leur utilisation
BE753314A (fr) Nouveaux pyridine-bis-(hydroxyaryl-ethers) et leur procede de preparation
BE750484A (fr) Nouveaux derives de benzomorphane et leur procede de production
BE745258A (fr) Nouveaux esters therapeutiquement actifs et leur procede de preparatio
BE760402A (fr) Nouveaux derives bis-aroxazolyliques, leur procede de preparation et leur utilisation
BE754380A (fr) Nouveaux colorants azoiques, leur procede de preparation et leur emplo
BE759460A (fr) Nouveaux carbamates et leur procede de preparation
BE820383A (fr) Nouveaux d-homo.steroides et leur procede de preparation
BE751923A (fr) Nouveaux aminoaryl-ethers et leur procede de preparation
BE754587A (fr) Nouveaux p-(trihalomethylquinolylamino) benzamides et leur procede de preparation
BE751562A (fr) 4-pyrazolidinols 1,2-disubstitues et leur procede de preparation
BE791196A (fr) Nouveaux steroides, leur procede de preparation et leurs applications
BE758621A (fr) Nouvelles amidines et leur procede de preparation
BE800121A (fr) Nouveaux triazolyl-naphtalimides et leur procede de preparation,
BE753632A (fr) Nitrofuryl-aminoalkoxy-pyrimidines et leur procede de preparation
BE749101A (fr) 3-(5-nitro-2-imidazolyl-methyleneamino)-2-oxazolidinones et leur procede de preparation
BE807803A (fr) Nouveaux triazolyl-stilbenes et leur procede de preparation

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19860331