BE751299A - Dna polyamine compositions for treating - lesions caused by radiation - Google Patents

Dna polyamine compositions for treating - lesions caused by radiation

Info

Publication number
BE751299A
BE751299A BE751299DA BE751299A BE 751299 A BE751299 A BE 751299A BE 751299D A BE751299D A BE 751299DA BE 751299 A BE751299 A BE 751299A
Authority
BE
Belgium
Prior art keywords
dna
radiation
lesions caused
treating
amino
Prior art date
Application number
Other languages
French (fr)
Original Assignee
Kakenyaku Kako Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kakenyaku Kako Kk filed Critical Kakenyaku Kako Kk
Publication of BE751299A publication Critical patent/BE751299A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DNA-polyamine composition for treating lesions caused by radiation. Compns. are prepared by dissolving dioxyri bonucleic acid (DNA) and a basic amine or amino-acid separately in dilute sodium chloride solution opt. containing sodium citrate, mixing the two solutions at 37 degrees C for 6-36 hrs. and at pH 7, adding ethanol and recovering the precipitate formed by centrifuging. Suitable amines and amino-acids are spermine, spermidine, cadaverine, polylysine and polyarginine. The compositions may be used to cure lesions caused by radiation e.g. white corpuscle destruction and can be used to treat secondary effects in the X-ray and gamma-ray treatments for cancer.
BE751299D 1970-06-01 1970-06-02 Dna polyamine compositions for treating - lesions caused by radiation BE751299A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE751299 1970-06-01

Publications (1)

Publication Number Publication Date
BE751299A true BE751299A (en) 1970-11-16

Family

ID=3856574

Family Applications (1)

Application Number Title Priority Date Filing Date
BE751299D BE751299A (en) 1970-06-01 1970-06-02 Dna polyamine compositions for treating - lesions caused by radiation

Country Status (1)

Country Link
BE (1) BE751299A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022792A1 (en) * 1995-01-25 1996-08-01 Amgen Inc. Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022792A1 (en) * 1995-01-25 1996-08-01 Amgen Inc. Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides

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