BE770625A - Procede de preparation d'analgesiques - Google Patents

Procede de preparation d'analgesiques

Info

Publication number
BE770625A
BE770625A BE770625A BE770625A BE770625A BE 770625 A BE770625 A BE 770625A BE 770625 A BE770625 A BE 770625A BE 770625 A BE770625 A BE 770625A BE 770625 A BE770625 A BE 770625A
Authority
BE
Belgium
Prior art keywords
preparation process
analgesic preparation
analgesic
preparation
Prior art date
Application number
BE770625A
Other languages
English (en)
Inventor
I J Pachter
M Gordon
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE770625A publication Critical patent/BE770625A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE770625A 1970-08-03 1971-07-28 Procede de preparation d'analgesiques BE770625A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6062170A 1970-08-03 1970-08-03

Publications (1)

Publication Number Publication Date
BE770625A true BE770625A (fr) 1972-01-28

Family

ID=22030682

Family Applications (1)

Application Number Title Priority Date Filing Date
BE770625A BE770625A (fr) 1970-08-03 1971-07-28 Procede de preparation d'analgesiques

Country Status (9)

Country Link
US (1) US3773955A (fr)
AU (1) AU463074B2 (fr)
BE (1) BE770625A (fr)
DE (1) DE2138593A1 (fr)
DK (1) DK133035B (fr)
FR (1) FR2101191B1 (fr)
GB (1) GB1353815A (fr)
NL (1) NL7109388A (fr)
ZA (1) ZA714683B (fr)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3885027A (en) * 1971-04-12 1975-05-20 West Laboratories Inc Orally administered drug composition for therapy in the treatment of narcotic drug addiction
US3896226A (en) * 1971-11-26 1975-07-22 Lewinstein Evalina 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts thereof, and use of the same as a narcotic antagonist
US3906100A (en) * 1973-05-24 1975-09-16 Miles Lab N-benzyl-N-{8 2-phenyl-2-(4-phenyl-1-piperidyl)-ethyl{9 -propionamide para-chlorobenzene sulfonate
US4048316A (en) * 1974-03-04 1977-09-13 Penn Nathar W Composition for antagonizing the narcotic effects of barbiturate addiction and withdrawal effects, and for treatment of barbiturate poisoning
US4126684A (en) * 1976-02-11 1978-11-21 Ciba-Geigy Corporation 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
US4457933A (en) * 1980-01-24 1984-07-03 Bristol-Myers Company Prevention of analgesic abuse
JPS56128715A (en) * 1980-03-06 1981-10-08 Bristol Myers Co Analgesic abuse prevention
US4366159A (en) * 1981-09-08 1982-12-28 Michael Richard Magruder Nalbuphine-narcotic analgesic composition and method of producing analgesia
DE3216327C1 (de) * 1982-05-03 1983-05-19 Siempelkamp Gießerei GmbH & Co, 4150 Krefeld Herstellung von dickwandigen Abschirmtransport- und Lagerbehältern aus sphärolitischem Gußeisen
EP0116538A4 (fr) * 1982-08-25 1985-04-25 Joel E Bernstein Methode et medicament de traitement du prurit.
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions
US4888346A (en) * 1986-10-07 1989-12-19 Bernard Bihari Method for the treatment of persons infected with HTLV-III (AIDS) virus
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
DE122004000032I2 (de) 1991-09-06 2006-02-09 Mcneilab Inc Zusammensetzung die eine Tramadol-Verbindung und Acetaminophen enth{lt, und ihre Verwendung
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5587381A (en) * 1995-03-27 1996-12-24 Sinclair; John D. Method for terminating methadone maintenance through extinction of the opiate-taking responses
BR9813826A (pt) 1997-12-22 2000-10-10 Euro Celtique Sa Potencial de uso abusivo de administração oral de opióide analgésico
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
EP2266564B1 (fr) 1997-12-22 2013-03-13 Euro-Celtique S.A. Formulation pharmaceutique pour administration orale comprenant en combinaison un agoniste et un antagoniste des récepteurs opiacés
CA2380524A1 (fr) * 1999-08-25 2001-03-01 Barrett R. Cooper Compositions et procedes permettant de traiter l'intolerance aux opiaces
US6716449B2 (en) 2000-02-08 2004-04-06 Euro-Celtique S.A. Controlled-release compositions containing opioid agonist and antagonist
EP2517710B1 (fr) 2000-02-08 2015-03-25 Euro-Celtique S.A. Formules agonistes opioïdes orales inviolables
CA2778114A1 (fr) * 2001-05-11 2002-11-21 Endo Pharmaceuticals, Inc. Forme posologique d'opioides empechant la consommation abusive
JP4522652B2 (ja) 2001-05-11 2010-08-11 エンドー ファーマシューティカルズ, インコーポレイティド 乱用防止制御放出オピオイド投薬形態
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7968119B2 (en) * 2001-06-26 2011-06-28 Farrell John J Tamper-proof narcotic delivery system
CA2454328C (fr) 2001-07-18 2008-03-18 Christopher D. Breder Combinaisons pharmaceutiques d'oxycodone et naloxone
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
MXPA04001210A (es) 2001-08-06 2004-07-08 Euro Celtique Sa Formulaciones de agonista opioide con antagonista liberable y aislado.
US20030157168A1 (en) 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
US20030068276A1 (en) * 2001-09-17 2003-04-10 Lyn Hughes Dosage forms
US20040126428A1 (en) * 2001-11-02 2004-07-01 Lyn Hughes Pharmaceutical formulation including a resinate and an aversive agent
LT2425824T (lt) * 2002-04-05 2017-07-25 Euro-Celtique S.A. Farmacinis preparatas, turintis oksikodono ir naloksono
US20030199439A1 (en) * 2002-04-22 2003-10-23 Simon David Lew Compositions of alpha3beta4 receptor antagonists and opioid agonist analgesics
WO2003090729A1 (fr) * 2002-04-23 2003-11-06 Alza Corporation Systemes analgesiques transdermiques avec risques d'abus reduits
US8557291B2 (en) * 2002-07-05 2013-10-15 Collegium Pharmaceutical, Inc. Abuse-deterrent pharmaceutical compositions of opioids and other drugs
US10004729B2 (en) 2002-07-05 2018-06-26 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
CA2491572C (fr) 2002-07-05 2010-03-23 Collegium Pharmaceutical, Inc. Compositions pharmaceutiques empechant la consommation abusive d'opioides et d'autres drogues
US8840928B2 (en) * 2002-07-05 2014-09-23 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
SI1551372T1 (en) 2002-09-20 2018-08-31 Alpharma Pharmaceuticals Llc SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US9579286B2 (en) * 2003-04-21 2017-02-28 Purdue Pharma L.P. Tamper resistant dosage form comprising co-extruded, sequestered adverse agent particles and process of making same
MY135852A (en) 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
AU2004235794B8 (en) 2003-04-30 2009-07-23 Purdue Pharma L.P. Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
EP2112920B1 (fr) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Capsules contenant un inhibiteur de la pompe a protons comprenant des unites secondaires differemment structurees permettant une liberation retardee de l'ingredient actif
CN1909892A (zh) 2003-10-30 2007-02-07 阿尔扎公司 具有降低的滥用可能性的透皮止痛剂系统
PL1691892T3 (pl) * 2003-12-09 2007-07-31 Euro Celtique Sa Odporna na fizyczne manipulowanie, współwytłaczana postać dawkowania zawierająca środek aktywny i środek przeciwdziałający oraz sposób wytwarzania tej postaci
US8883204B2 (en) 2003-12-09 2014-11-11 Purdue Pharma L.P. Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
US20050126562A1 (en) * 2003-12-15 2005-06-16 Alexza Molecular Delivery Corporation Treatment of breakthrough pain by drug aerosol inhalation
US20050165038A1 (en) * 2004-01-22 2005-07-28 Maxwell Gordon Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects
HRP20090203T1 (en) * 2004-03-30 2009-05-31 Euro-Celtique S.A. Tamper resistant dosage form comprising an adsorbent and an adverse agent
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP1604667A1 (fr) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioides pour le traitement des impatiences des membres inférieurs
EP1604666A1 (fr) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioides pour le traitement de la bronchopneumopathie chronique obstructive
DK1765292T3 (en) * 2004-06-12 2018-01-02 Collegium Pharmaceutical Inc ABUSE PREVENTIONAL PHARMACEUTICAL FORMULATIONS
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
CN101005833A (zh) * 2004-08-20 2007-07-25 3M创新有限公司 具有半透明保护膜的透皮药物递送装置
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP3228308A1 (fr) * 2005-01-28 2017-10-11 Euro-Celtique S.A. Formes posologiques résistantes à l'alcool
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
EP1702558A1 (fr) 2005-02-28 2006-09-20 Euro-Celtique S.A. Procédé et dispositif pour évaluer la fonction de l'activité intestinale
EP1695700A1 (fr) * 2005-02-28 2006-08-30 Euro-Celtique S.A. Forme posologique contenant de l'oxycodone et de la naloxone
DE602006016441D1 (de) * 2005-05-13 2010-10-07 Alza Corp Mehrlagiges arzneimittelausbringsystem mit sperre gegen reservoirmaterialfluss
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
WO2006133103A2 (fr) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Reservoir pour l'administration d'agents
US9125833B2 (en) * 2005-11-02 2015-09-08 Relmada Therapeutics, Inc. Multimodal abuse resistant and extended release opioid formulations
US8329744B2 (en) * 2005-11-02 2012-12-11 Relmada Therapeutics, Inc. Methods of preventing the serotonin syndrome and compositions for use thereof
WO2007056142A2 (fr) * 2005-11-02 2007-05-18 Theraquest Biosciences, Llc Procedes de prevention du syndrome serotoninergique et compositions utilisees a cette fin
US20090082466A1 (en) * 2006-01-27 2009-03-26 Najib Babul Abuse Resistant and Extended Release Formulations and Method of Use Thereof
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP1810670A1 (fr) * 2006-01-19 2007-07-25 Holger Lars Hermann Combinaison de Polamidone et de Naloxone dans le traitement de la toxicomanie
FR2898056B1 (fr) * 2006-03-01 2012-01-20 Ethypharm Sa Comprimes resistant a l'ecrasement destines a eviter le detournement illicite
WO2007112581A1 (fr) 2006-04-03 2007-10-11 Isa Odidi Dispositif d'administration à libération commandée comprenant un enrobage organosol
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US20070278289A1 (en) * 2006-05-31 2007-12-06 Toshiba Tec Kabushiki Kaisha Payment adjusting apparatus and program therefor
EP2719378B1 (fr) 2006-06-19 2016-08-31 Alpharma Pharmaceuticals LLC Compositions pharmaceutiques
EP1897543A1 (fr) 2006-08-30 2008-03-12 Euro-Celtique S.A. Gaufre de buprénorphine pour la thérapie de substitution
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US7748244B2 (en) * 2007-09-14 2010-07-06 Schlage Lock Company Deadbolt lock assembly
US20100239523A1 (en) * 2007-10-30 2010-09-23 The Regents Of The University Of Colorado Tlr modulators and methods for using the same
WO2009059048A2 (fr) * 2007-10-30 2009-05-07 The Regents Of The University Of Colorado Opioïdes-(+) et méthodes d'utilisation
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
HUE042105T2 (hu) 2009-03-10 2019-06-28 Euro Celtique Sa Oxikodont és naloxont tartalmazó azonnali hatóanyagleadású orális gyógyászati készítmények
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
EP2675436A1 (fr) 2011-02-17 2013-12-25 Qrxpharma Limited Technologie pour prévenir l'abus de formes pharmaceutiques solides
EP3024461B1 (fr) 2013-07-23 2020-05-13 Euro-Celtique S.A. Combinaison d'oxycodone et de la naloxone pour utilisation dans le traitement de la douleur chez des patients souffrant de douleurs et d'une maladie résultant de dysbioses intestinales et/ou augmentant le risque de la la translocation bacterienne
DE202016005375U1 (de) 2015-09-03 2016-09-30 Acino Pharma Ag Verminderung der Deallylierung von Naloxon während der Lagerung einer naloxonhaltigen Retardformulierung
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
CA2972220C (fr) 2016-06-29 2023-01-24 Disposerx, Inc. Elimination de medicaments
EP3709984B1 (fr) 2017-11-15 2026-03-11 The Regents of the University of California Combinaison de cannabidiol et de buprénorphine et son utilisation pour le traitement de la douleur chronique
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Also Published As

Publication number Publication date
FR2101191A1 (fr) 1972-03-31
DE2138593A1 (de) 1972-03-30
AU3185671A (en) 1973-02-01
US3773955A (en) 1973-11-20
GB1353815A (en) 1974-05-22
AU463074B2 (en) 1975-07-17
NL7109388A (fr) 1972-02-07
DK133035B (da) 1976-03-15
ZA714683B (en) 1972-04-26
FR2101191B1 (fr) 1975-02-07

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