BE773789Q - 5-Dibenzo-/b:c/-/1:4/-diazepineamidines (wherein R is S, SO, or -NR1-, where R1 is H, a dissociatable group such as acyl, alkyl or akenyl with 1-5C atoms or a - Google Patents
5-Dibenzo-/b:c/-/1:4/-diazepineamidines (wherein R is S, SO, or -NR1-, where R1 is H, a dissociatable group such as acyl, alkyl or akenyl with 1-5C atoms or aInfo
- Publication number
- BE773789Q BE773789Q BE773789A BE773789A BE773789Q BE 773789 Q BE773789 Q BE 773789Q BE 773789 A BE773789 A BE 773789A BE 773789 A BE773789 A BE 773789A BE 773789 Q BE773789 Q BE 773789Q
- Authority
- BE
- Belgium
- Prior art keywords
- alkyl
- dibenzo
- atoms
- diazepine
- opt
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 title abstract 6
- 125000002252 acyl group Chemical group 0.000 title abstract 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000006310 cycloalkyl amino group Chemical group 0.000 abstract 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- -1 pyrrolidino, piperidino, morpholino Chemical group 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Dibenzo-/b:c/-/1:4/-diazepineamidines (wherein R is S, SO, or -NR1-, where R1 is H, a dissociatable group such as acyl, alkyl or akenyl with 1-5C atoms or a group -X-Y, where X 1-5C hydrocarbon, and Y is aminodialkyl, e.g. dimethylamine or diethylamino, or a cycloalkylamino opt. contng. other heteroatoms, esp. O, S or N, which may have common C atoms with X, the N atoms of the ring may carry H, alkyl, hydroxyalkyl or alkoxyalkyl, e.g. pyrrolidino, piperidino, morpholino, or N2-methylpiperazino; R2 and R3 are H, aryl, or aralkyl which may have substnts. of the same nature as R4, alkenyl or alkyl with 1-5C atoms, opt. together forming a ring which may contain other heteroatoms, such as O, S or N, opt. substd. on the N by alkyl, hydroxyalkyl or alkoxyalkyl, or amino or aminoalkyl, which may be alkylated; and R4 and R5 are H, halogen, hydroxy, alkyl, alkoxy or alkylmercapto contng. 1-3C, or trifluoromethyl). Typical are 8-chloro-11-N-methylpiperazino-5-dibenzo-(b:e)(1:4)-diazepine, 5-methyl-11-amino-5-dibenzo-(b:e)(1:4)-diazepine, and 11-piperidino-5-dibenzo-(b:e)(1:4)-diazepine, and their hydrochlorides and maleates. They may be used in unit doses of 10-30mg active material for tablets and suppositories and 5-15 mg of injectable solns.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES26984562 | 1962-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE773789Q true BE773789Q (en) | 1972-04-11 |
Family
ID=8423841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE773789A BE773789Q (en) | 1962-02-09 | 1971-10-11 | 5-Dibenzo-/b:c/-/1:4/-diazepineamidines (wherein R is S, SO, or -NR1-, where R1 is H, a dissociatable group such as acyl, alkyl or akenyl with 1-5C atoms or a |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE773789Q (en) |
-
1971
- 1971-10-11 BE BE773789A patent/BE773789Q/en active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3674483D1 (en) | MULTI-CHAMBER SYRINGE. | |
| CH503698A (en) | Process for the preparation of amides of N-acylcysteines | |
| BR6570272D0 (en) | PROCESS FOR THE PREPARATION OF NEW 1,4-DISSUBSTITUTED DERIVATIVES OF PIPERAZINE AND DIAZEPINE | |
| ES335760A1 (en) | Process for 11 - aminodibenz(b,f)(1,4)oxazepines and analogous thiazepines | |
| GB1191253A (en) | New Compositions of Matter | |
| DE3783657D1 (en) | PEPTIDES WITH INFLUENCE ON DIURESE AND NATURALSE, METHOD FOR THE PRODUCTION THEREOF, THE CONTAINERS THEREOF AND THEIR USE. | |
| CH450822A (en) | Axial bearing and process for its manufacture | |
| IT7924233A0 (en) | DEVICE FOR FEEDING LUBRICANT INTO THE CYLINDER BARREL OF AN INTERNAL COMBUSTION MACHINE. | |
| ES392094A1 (en) | 2-amino-5-chloro-thiazole derivatives | |
| FI46380C (en) | Process for the preparation of blood-lowering and sedative derivatives of 2- (2-haloanilino) -1,3-diazacyclopentenes- (2). | |
| GB1035683A (en) | New estrane derivatives, compositions incorporating them and processes for their preparation | |
| ES381989A1 (en) | 11-aminoalkylidenemorphanthridines | |
| ES348433A1 (en) | Dibenzo (c f) thiazepine (1 2) compounds | |
| ES402613A1 (en) | PROCEDURE TO PREPARE NEW ISOPROPIL-2-TETRAHIDROO-XAZINAS - 1,3 SUBSTITUTED. | |
| FR2138488A1 (en) | 1-(5-indanyl)-omega-aminoalkanes - with tranquillizing activity | |
| ES409363A1 (en) | Method of purifying secondary ammonium N,N-disubstituted thiolcarbamates | |
| GB1015784A (en) | 10 - substituted 1,3 - diazaphenothiazines | |
| ES361018A1 (en) | Procedure for obtaining salts from biosintetic and semi-synthetic penicillins with N-substituted derivatives of aminocetil-2-metoxifenol. (Machine-translation by Google Translate, not legally binding) | |
| FR2131826A1 (en) | 3-carbonyl and thiocarbonyl-2-aminoindoles - with sedative activity | |
| GB1119836A (en) | Pharmaceutical compositions containing basic ethers | |
| GB1252460A (en) | ||
| FR1602876A (en) | Azadibenzocycloheptene-5-ol ethers ethers | |
| FR2260332A1 (en) | 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity | |
| GB1117622A (en) | New tertiary amines and process for their manufacture | |
| ES385521A1 (en) | Azamorphinan compounds |