BE779841R - Sulphonyloxy-13-beta-ethyl-gonanes - as oestrogenic-genic anti-fecundity and anti-lipaemic agents - Google Patents
Sulphonyloxy-13-beta-ethyl-gonanes - as oestrogenic-genic anti-fecundity and anti-lipaemic agentsInfo
- Publication number
- BE779841R BE779841R BE779841A BE779841A BE779841R BE 779841 R BE779841 R BE 779841R BE 779841 A BE779841 A BE 779841A BE 779841 A BE779841 A BE 779841A BE 779841 R BE779841 R BE 779841R
- Authority
- BE
- Belgium
- Prior art keywords
- beta
- ethyl
- lipaemic
- gonanes
- oestrogenic
- Prior art date
Links
- -1 Sulphonyloxy-13-beta-ethyl-gonanes Chemical class 0.000 title abstract 5
- 230000002402 anti-lipaemic effect Effects 0.000 title 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- WAQFVHDESWWOPB-UHFFFAOYSA-N trimethyl(trimethylsilyloxyperoxy)silane Chemical compound C[Si](C)(C)OOO[Si](C)(C)C WAQFVHDESWWOPB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Cpds. (I) and (II) (where R1 is alkyl, alicyclyl, aralkyl, N,N-dialkylamino or polymethylene-imino, R2 is OH, acyloxy, alkoxy or trimethylsiloxy and R3 is H, alkyl, alkenyl, alkynyl or R2 + R3 = O) are prepd. by esterifying the corresponding hydroxy cpd. with a sulphonyl halide. Thus (I, R1 = Pr, R2 = OH, R3 = ethinyl) is prepd. from PrSO2Cl and 3-hydroxy-16 beta-ethyl-17 alpha-ethinyl-17 beta-trimethylsiloxy-1,3,5(10)-gonatrienes in the presence of Et3N and hydrolysing the trimethylsiloxy ether.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE779841A BE779841R (en) | 1972-02-25 | 1972-02-25 | Sulphonyloxy-13-beta-ethyl-gonanes - as oestrogenic-genic anti-fecundity and anti-lipaemic agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE779841A BE779841R (en) | 1972-02-25 | 1972-02-25 | Sulphonyloxy-13-beta-ethyl-gonanes - as oestrogenic-genic anti-fecundity and anti-lipaemic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE779841R true BE779841R (en) | 1972-06-16 |
Family
ID=3859311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE779841A BE779841R (en) | 1972-02-25 | 1972-02-25 | Sulphonyloxy-13-beta-ethyl-gonanes - as oestrogenic-genic anti-fecundity and anti-lipaemic agents |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE779841R (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993005063A1 (en) * | 1991-08-29 | 1993-03-18 | Imperial College Of Science, Technology And Medicine | Steroid sulphatase inhibitors |
-
1972
- 1972-02-25 BE BE779841A patent/BE779841R/en active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993005063A1 (en) * | 1991-08-29 | 1993-03-18 | Imperial College Of Science, Technology And Medicine | Steroid sulphatase inhibitors |
| US5604215A (en) * | 1991-08-29 | 1997-02-18 | Imperial College Of Science, Technology And Medicine | Steroid sulphatase inhibitors |
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