BE788209A - Derives tetrazoyliques des prostaglandines naturelles - Google Patents

Derives tetrazoyliques des prostaglandines naturelles

Info

Publication number
BE788209A
BE788209A BE788209DA BE788209A BE 788209 A BE788209 A BE 788209A BE 788209D A BE788209D A BE 788209DA BE 788209 A BE788209 A BE 788209A
Authority
BE
Belgium
Prior art keywords
tetrazoyl
derivatives
natural prostaglandins
prostaglandins
natural
Prior art date
Application number
Other languages
English (en)
Inventor
H-J E Hess
Th K Schaaf
L J Czuba
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE788209A publication Critical patent/BE788209A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/16—Dicarboxylic acids and dihydroxy compounds
    • C08G63/18—Dicarboxylic acids and dihydroxy compounds the acids or hydroxy compounds containing carbocyclic rings
    • C08G63/19—Hydroxy compounds containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE788209D 1971-09-01 Derives tetrazoyliques des prostaglandines naturelles BE788209A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17710271A 1971-09-01 1971-09-01
US335586A US3883513A (en) 1971-09-01 1973-02-26 Tetrazoyl derivatives of naturally occurring prostaglandins
US501189A US3928391A (en) 1971-09-01 1974-08-27 Certain cyclopentafuran diols substituted by certain-3-hydroxyalkyl (or alkenyl) groups useful in the preparation of prostaglandin analogs

Publications (1)

Publication Number Publication Date
BE788209A true BE788209A (fr) 1973-02-28

Family

ID=27390778

Family Applications (2)

Application Number Title Priority Date Filing Date
BE788209D BE788209A (fr) 1971-09-01 Derives tetrazoyliques des prostaglandines naturelles
BE1005745A BE811556A (fr) 1971-09-01 1974-02-26 Derives tetrazolyliques des prostaglandines naturelles

Family Applications After (1)

Application Number Title Priority Date Filing Date
BE1005745A BE811556A (fr) 1971-09-01 1974-02-26 Derives tetrazolyliques des prostaglandines naturelles

Country Status (10)

Country Link
US (2) US3883513A (fr)
JP (1) JPS5029564A (fr)
AT (1) AT339901B (fr)
BE (2) BE811556A (fr)
CA (1) CA1030150A (fr)
CH (5) CH558386A (fr)
DE (2) DE2242239C2 (fr)
FR (2) FR2151053B1 (fr)
GB (4) GB1373461A (fr)
NL (2) NL173956C (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788209A (fr) * 1971-09-01 1973-02-28 Pfizer Derives tetrazoyliques des prostaglandines naturelles
US3980642A (en) * 1972-07-13 1976-09-14 Pfizer Inc. 15-Substitute D-ω-pentanorprostaglandins
US4143051A (en) * 1972-07-13 1979-03-06 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
US3962312A (en) * 1972-09-21 1976-06-08 Ono Pharmaceutical Company 9,11,15-Trihydroxy prost-5-enoic acid analogues
US4024179A (en) * 1972-11-08 1977-05-17 Pfizer Inc. Substituted ω-pentanorprostaglandins
US3932389A (en) * 1974-12-11 1976-01-13 Pfizer Inc. 2-Descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-.omega.-pentanorprostaglandins
MX3291E (es) * 1975-04-23 1980-08-22 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
DE2559093C3 (de) * 1975-12-30 1981-12-24 Pfizer Inc., 10017 New York, N.Y. 2-Desarboxy-2-[tetrazol-5-yl]-11-desoxy-ω-pentanorprostaglandine der E- oder F-Reihe und deren C↓15↓-Epimere
US4043339A (en) * 1976-02-02 1977-08-23 The Upjohn Company Method of and vaginal insert for prostaglandin administration
US4410695A (en) * 1976-02-04 1983-10-18 The Upjohn Company 2-Decarboxy-2-tetrazolyl-6-keto-PG compounds
US4091207A (en) * 1976-04-22 1978-05-23 Pfizer Inc. Prostaglandin intermediate including oxathio heterocyclic ring
US4092349A (en) * 1976-11-10 1978-05-30 Pfizer Inc. 11-Desoxy-15-thiaprostaglandins
US4366313A (en) * 1977-09-02 1982-12-28 The Upjohn Company 2-Decarboxy-2-tetrazolyl-6-keto-PGE1 compounds
US4148804A (en) * 1978-01-11 1979-04-10 Pfizer Inc. 2-Descarboxy-2-(tetrazol-5-yl) 11-desoxy-15-thiaprostaglandins
IN150279B (fr) * 1978-01-16 1982-09-04 Pfizer
US4497827A (en) * 1982-08-30 1985-02-05 Syntex (U.S.A.) Inc. Arachidonic acid analogues as anti-inflammatory and anti-allergic agents
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
JPH0656079B2 (ja) * 1987-10-09 1994-07-27 株式会社熊谷組 水中への構造物の設置方法
US6323190B1 (en) * 1998-07-31 2001-11-27 The Univeristy Of Georgia Research Foundation, Inc. Estrogen mimetics lacking reproductive tract effects
PT2343292E (pt) 2008-09-10 2014-11-04 Kaken Pharma Co Ltd Novo derivado de prostaglandina i2
CN102917703B (zh) 2010-03-08 2015-08-19 科研制药株式会社 新型ep4激动剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3711515A (en) * 1970-11-27 1973-01-16 Upjohn Co Tricyclic lactone alkene or alkenyne
BE788209A (fr) * 1971-09-01 1973-02-28 Pfizer Derives tetrazoyliques des prostaglandines naturelles

Also Published As

Publication number Publication date
DE2242239C2 (de) 1981-12-03
NL7402606A (fr) 1974-08-28
GB1373462A (en) 1974-11-13
US3928391A (en) 1975-12-23
ATA157174A (de) 1977-03-15
NL7211860A (fr) 1973-03-05
GB1458266A (en) 1976-12-15
CH561204A5 (fr) 1975-04-30
DE2409601A1 (de) 1974-09-12
AT339901B (de) 1977-11-10
AU6592974A (en) 1975-08-28
FR2270252B2 (fr) 1979-05-18
AU4594672A (en) 1974-02-28
CH566332A5 (fr) 1975-09-15
JPS5029564A (fr) 1975-03-25
NL173956C (nl) 1983-11-01
CH553795A (fr) 1974-09-13
FR2151053A1 (fr) 1973-04-13
US3883513A (en) 1975-05-13
CH558386A (fr) 1975-01-31
GB1373461A (en) 1974-11-13
CA1030150A (fr) 1978-04-25
CH572048A5 (fr) 1976-01-30
FR2270252A2 (fr) 1975-12-05
FR2151053B1 (fr) 1978-07-28
DE2242239A1 (de) 1973-03-22
GB1373463A (en) 1974-11-13
BE811556A (fr) 1974-08-26
NL173956B (nl) 1983-11-01

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC.

Effective date: 19860831