BE808416A - Bicyclische imidazolen en pyrimidinen met farmacologische werking - Google Patents

Bicyclische imidazolen en pyrimidinen met farmacologische werking

Info

Publication number
BE808416A
BE808416A BE138675A BE138675A BE808416A BE 808416 A BE808416 A BE 808416A BE 138675 A BE138675 A BE 138675A BE 138675 A BE138675 A BE 138675A BE 808416 A BE808416 A BE 808416A
Authority
BE
Belgium
Prior art keywords
farmacologische
pyrimidinen
imidazolen
bicyclische
werking
Prior art date
Application number
BE138675A
Other languages
English (en)
Inventor
De J L H Van Gelder
A H M Raeymaekers
L F C Roevens
W J Van Laerhoven
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BE808416A publication Critical patent/BE808416A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
    • C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE138675A 1972-12-08 1973-12-10 Bicyclische imidazolen en pyrimidinen met farmacologische werking BE808416A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US313285A US3865836A (en) 1972-12-08 1972-12-08 Bicyclic imidazoles

Publications (1)

Publication Number Publication Date
BE808416A true BE808416A (fr) 1974-06-10

Family

ID=23215116

Family Applications (1)

Application Number Title Priority Date Filing Date
BE138675A BE808416A (fr) 1972-12-08 1973-12-10 Bicyclische imidazolen en pyrimidinen met farmacologische werking

Country Status (23)

Country Link
US (1) US3865836A (fr)
JP (1) JPS4994694A (fr)
AT (1) AT333770B (fr)
BE (1) BE808416A (fr)
BG (1) BG21608A3 (fr)
CA (1) CA1010864A (fr)
CH (1) CH593975A5 (fr)
DE (1) DE2361188A1 (fr)
DK (1) DK141289B (fr)
FI (1) FI54711C (fr)
FR (1) FR2209576B1 (fr)
GB (1) GB1446482A (fr)
HU (1) HU168638B (fr)
IE (1) IE38618B1 (fr)
IL (1) IL43770A (fr)
NL (1) NL7316778A (fr)
NO (1) NO139087C (fr)
PH (1) PH10417A (fr)
PL (1) PL94683B1 (fr)
RO (1) RO63263A (fr)
SE (1) SE411627B (fr)
SU (1) SU578003A3 (fr)
ZA (1) ZA739343B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181927B (en) * 1977-07-06 1983-11-28 Iso Pharmachim Process for producing r,s-2,3,5,6-tetrahydro-6-phenyl-imidazo-bracket-2,1-b-bracket closed thiazol /tetramizol/
BG25138A1 (en) * 1977-07-06 1978-08-10 Georgiev A method of obtaining of rs-(+/-)-2,3,5,6-tetrahydro-6-phenylimidazo-(2,1-b)-thiazol(tetramizol)
DE2827617A1 (de) * 1978-06-23 1980-01-10 Boehringer Sohn Ingelheim Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US4370500A (en) * 1978-11-06 1983-01-25 American Cyanamid Company Compound: d-N-(2-amino-2-phenethyl)-2-methoxyethylamine and process for preparing the same by selective crystallization
DE3042636A1 (de) * 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
GB8509531D0 (en) * 1985-04-13 1985-05-15 Bp Chem Int Ltd Preparation of guanidines
US6359144B1 (en) * 1997-02-04 2002-03-19 Lion Bioscience Ag Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
US6888004B2 (en) * 2001-01-26 2005-05-03 Bristol-Myers Squibb Company Imidazolyl derivatives as corticotropin releasing factor inhibitors
WO2003027115A1 (fr) * 2001-09-21 2003-04-03 Sanofi-Synthelabo Derives de 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidine-4-one et de 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1h)one utilises pour le traitement de maladies neurodegeneratives
ATE482214T1 (de) * 2005-06-14 2010-10-15 Schering Corp Aspartylproteasehemmer
US8563560B2 (en) * 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB796996A (en) * 1956-03-29 1958-06-25 Monsanto Canada Ltd Imidazole derivatives
GB805877A (en) * 1957-01-28 1958-12-17 Monsanto Canada Ltd Process for the production of 2, 3, 5, 6-tetrahydro-1-imidaz (1, 2-a) imidazole

Also Published As

Publication number Publication date
RO63263A (fr) 1978-08-15
FR2209576A1 (fr) 1974-07-05
GB1446482A (en) 1976-08-18
BG21608A3 (fr) 1976-07-20
SE411627B (sv) 1980-01-21
DK141289B (da) 1980-02-18
FI54711B (fi) 1978-10-31
JPS4994694A (fr) 1974-09-09
FR2209576B1 (fr) 1977-01-28
DK141289C (fr) 1980-08-11
SU578003A3 (ru) 1977-10-25
NO139087C (no) 1979-01-03
NL7316778A (fr) 1974-06-11
IL43770A (en) 1976-08-31
IL43770A0 (en) 1974-03-14
PH10417A (en) 1977-03-16
AU6337173A (en) 1975-06-12
ATA1026573A (de) 1976-04-15
NO139087B (no) 1978-09-25
HU168638B (fr) 1976-06-28
CA1010864A (en) 1977-05-24
US3865836A (en) 1975-02-11
DE2361188A1 (de) 1974-06-12
ZA739343B (en) 1975-07-30
PL94683B1 (pl) 1977-08-31
IE38618B1 (en) 1978-04-26
AT333770B (de) 1976-12-10
CH593975A5 (fr) 1977-12-30
FI54711C (fi) 1979-02-12
IE38618L (en) 1974-06-08

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