BE839382A - Nouveaux derives d'acide para-(aryl(alkyl ou alcenyl)-amino-benzoique, et leur utilisation comme agents antilipidemiques - Google Patents

Nouveaux derives d'acide para-(aryl(alkyl ou alcenyl)-amino-benzoique, et leur utilisation comme agents antilipidemiques

Info

Publication number
BE839382A
BE839382A BE165004A BE165004A BE839382A BE 839382 A BE839382 A BE 839382A BE 165004 A BE165004 A BE 165004A BE 165004 A BE165004 A BE 165004A BE 839382 A BE839382 A BE 839382A
Authority
BE
Belgium
Prior art keywords
alcenyl
para
aryl
amino
alkyl
Prior art date
Application number
BE165004A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE839382A publication Critical patent/BE839382A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
BE165004A 1975-03-12 1976-03-10 Nouveaux derives d'acide para-(aryl(alkyl ou alcenyl)-amino-benzoique, et leur utilisation comme agents antilipidemiques BE839382A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/557,550 US4185115A (en) 1975-03-12 1975-03-12 Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives

Publications (1)

Publication Number Publication Date
BE839382A true BE839382A (fr) 1976-09-10

Family

ID=24225890

Family Applications (1)

Application Number Title Priority Date Filing Date
BE165004A BE839382A (fr) 1975-03-12 1976-03-10 Nouveaux derives d'acide para-(aryl(alkyl ou alcenyl)-amino-benzoique, et leur utilisation comme agents antilipidemiques

Country Status (24)

Country Link
US (1) US4185115A (fr)
JP (1) JPS51113838A (fr)
AR (1) AR215241A1 (fr)
AU (1) AU504690B2 (fr)
BE (1) BE839382A (fr)
CH (1) CH628614A5 (fr)
CS (1) CS212758B2 (fr)
DD (1) DD125926A5 (fr)
DE (1) DE2609962A1 (fr)
ES (1) ES445994A1 (fr)
FR (2) FR2303534A1 (fr)
GB (1) GB1535967A (fr)
HK (1) HK69179A (fr)
HU (1) HU173416B (fr)
IE (1) IE44285B1 (fr)
IL (1) IL49012A (fr)
MX (1) MX3788E (fr)
NL (1) NL7602332A (fr)
PL (1) PL112967B1 (fr)
RO (1) RO71822A (fr)
SE (1) SE7602869L (fr)
SU (1) SU803856A3 (fr)
YU (1) YU47676A (fr)
ZA (1) ZA76902B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576841A (en) * 1977-01-22 1980-10-15 Beecham Group Ltd Substituted n-acyl phenylamine compounds having hypolipidaemic activity
US4192884A (en) 1977-04-07 1980-03-11 The Dow Chemical Company Substituted 4-(((thienyl)methyl)-amino)benzoic acids and a method for treating hypolipidemia
CH629796A5 (en) * 1977-04-07 1982-05-14 Dow Chemical Co Therapeutically active compounds of 4-(2-thienylmethylamino)benzoic acid
US4230878A (en) 1978-03-08 1980-10-28 American Cyanamid Company Hypolipidemic and antiatherosclerotic 4-[(cyclopropyl alkyl)amino]benzoic acids and derivatives
IL56517A0 (en) * 1978-02-02 1979-03-12 American Cyanamid Co Novel 4-(cycloalkyl or cyclalkenyl substituted) amino, alkylamino or alkenylamino benzoic acids, salts and derivatives
US4178385A (en) 1978-03-03 1979-12-11 The Dow Chemical Company Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid
US4181737A (en) 1978-05-18 1980-01-01 The Dow Chemical Company 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof
DE2964790D1 (en) * 1978-06-23 1983-03-24 Dow Chemical Co Hypoglycemic phenylpropynylamino benzoic acids, their salts, pharmaceutical compositions containing said compounds and their application
US4207330A (en) * 1978-07-03 1980-06-10 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
US4206223A (en) * 1979-01-05 1980-06-03 The Dow Chemical Company Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof
US4281019A (en) * 1979-02-01 1981-07-28 American Cyanamid Company 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents
US4263320A (en) * 1979-06-04 1981-04-21 The Dow Chemical Company Hypoglycemic phenylpropynylamino benzoic acids
US4375478A (en) * 1982-03-02 1983-03-01 Abbott Laboratories Aminobenzoic acid derivatives
US7214825B2 (en) * 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
KR20060121768A (ko) * 2005-05-25 2006-11-29 주식회사 중외제약 테트라플루오로벤질 아닐린 유도체 및 이의 약학적으로허용가능한 염 화합물의 제조방법
WO2008121570A1 (fr) * 2007-03-29 2008-10-09 Irm Llc Composés et procédés pour moduler des récepteurs couplés à la protéine g
CN109206333A (zh) * 2018-10-16 2019-01-15 河南师范大学 一种具有抗菌活性的苯佐卡因单取代衍生物的合成方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868416A (en) * 1973-10-01 1975-02-25 American Cyanamid Co Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives
GB1576007A (en) * 1976-02-11 1980-10-01 Beecham Group Ltd Hypolipidaemic compositions

Also Published As

Publication number Publication date
GB1535967A (en) 1978-12-13
US4185115A (en) 1980-01-22
AR215241A1 (es) 1979-09-28
DD125926A5 (fr) 1977-06-01
DE2609962A1 (de) 1976-09-30
AU1103676A (en) 1977-08-18
YU47676A (en) 1983-04-30
CH628614A5 (de) 1982-03-15
MX3788E (es) 1981-07-20
JPS51113838A (en) 1976-10-07
SE7602869L (sv) 1976-12-06
ES445994A1 (es) 1977-10-01
HU173416B (hu) 1979-05-28
IE44285L (en) 1976-09-12
FR2303534B1 (fr) 1981-08-28
SU803856A3 (ru) 1981-02-07
IL49012A0 (en) 1976-04-30
FR2436132A1 (fr) 1980-04-11
ZA76902B (en) 1977-01-26
HK69179A (en) 1979-10-05
RO71822A (fr) 1982-02-01
IE44285B1 (en) 1981-10-07
IL49012A (en) 1980-12-31
FR2303534A1 (fr) 1976-10-08
CS212758B2 (en) 1982-03-26
PL112967B1 (en) 1980-11-29
AU504690B2 (en) 1979-10-25
NL7602332A (nl) 1976-09-14

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