BE853874A - Procede de preparation d'insuline au moyen de cellules fongiques genetiquement transformees - Google Patents
Procede de preparation d'insuline au moyen de cellules fongiques genetiquement transformeesInfo
- Publication number
- BE853874A BE853874A BE176944A BE176944A BE853874A BE 853874 A BE853874 A BE 853874A BE 176944 A BE176944 A BE 176944A BE 176944 A BE176944 A BE 176944A BE 853874 A BE853874 A BE 853874A
- Authority
- BE
- Belgium
- Prior art keywords
- fungal cells
- genetically transformed
- preparing insulin
- transformed fungal
- insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 230000002538 fungal effect Effects 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/679,565 US4082613A (en) | 1976-04-23 | 1976-04-23 | Process for the production of insulin by genetically transformed fungal cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE853874A true BE853874A (fr) | 1977-08-16 |
Family
ID=24727433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE176944A BE853874A (fr) | 1976-04-23 | 1977-04-22 | Procede de preparation d'insuline au moyen de cellules fongiques genetiquement transformees |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4082613A (fr) |
| JP (1) | JPS52151794A (fr) |
| BE (1) | BE853874A (fr) |
| CA (1) | CA1077870A (fr) |
| CH (1) | CH629533A5 (fr) |
| DE (1) | DE2717782A1 (fr) |
| DK (1) | DK178777A (fr) |
| FR (1) | FR2348971A1 (fr) |
| GB (1) | GB1570453A (fr) |
| IT (1) | IT1080447B (fr) |
| NL (1) | NL7704409A (fr) |
| SE (1) | SE7704689L (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
| US5583013A (en) * | 1977-11-08 | 1996-12-10 | Genentech, Inc. | Method and means for microbial polypeptide expression |
| US4704362A (en) * | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| JPS54163600A (en) * | 1977-11-08 | 1979-12-26 | Genentech Inc | Microbiological polypeptide expression method and means |
| US5221619A (en) * | 1977-11-08 | 1993-06-22 | Genentech, Inc. | Method and means for microbial polypeptide expression |
| DE2757169A1 (de) * | 1977-12-22 | 1979-07-05 | Hoechst Ag | Verfahren zur gewinnung insulin produzierender tierischer zellen |
| US4411994A (en) * | 1978-06-08 | 1983-10-25 | The President And Fellows Of Harvard College | Protein synthesis |
| JPS5519239A (en) * | 1978-07-28 | 1980-02-09 | Green Cross Corp:The | Interferon-producing attractant |
| FI792481A7 (fi) * | 1978-08-11 | 1981-01-01 | The Regents Of The Univ Of | Enkaroyyttisen proteiinin synteesi mikro-organismia käyttäen. |
| US4298002A (en) * | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation |
| DE3001928A1 (de) * | 1980-01-19 | 1981-08-06 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
| US4338397A (en) * | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
| US4332893A (en) * | 1980-06-13 | 1982-06-01 | Rosenberg Ralph A | Process for the production of an insulin-producing cell line of pancreatic beta cells |
| ZA808097B (en) * | 1980-12-29 | 1982-01-27 | Lilly Co Eli | Novel insulin formulations |
| ZA824218B (en) * | 1981-06-29 | 1983-04-27 | Cetus Corp | Plasmid for producing human insulin |
| ATE25197T1 (de) * | 1982-05-12 | 1987-02-15 | Harvard College | Hybridproteinekodierende fusionierte gene, sie enthaltende klonierungsvektoren und deren verwendung. |
| DK601984D0 (da) * | 1984-12-14 | 1984-12-14 | Hansens Lab | Fremgangsmaade til fremstilling af genprodukter |
| US5571783A (en) * | 1993-03-09 | 1996-11-05 | Clintec Nutrition Company | Composition and method for treating patients with hepatic disease |
-
1976
- 1976-04-23 US US05/679,565 patent/US4082613A/en not_active Expired - Lifetime
-
1977
- 1977-04-21 CA CA276,618A patent/CA1077870A/fr not_active Expired
- 1977-04-21 DE DE19772717782 patent/DE2717782A1/de not_active Withdrawn
- 1977-04-22 SE SE7704689A patent/SE7704689L/xx unknown
- 1977-04-22 DK DK178777A patent/DK178777A/da not_active Application Discontinuation
- 1977-04-22 CH CH506777A patent/CH629533A5/de not_active IP Right Cessation
- 1977-04-22 IT IT49101/77A patent/IT1080447B/it active
- 1977-04-22 NL NL7704409A patent/NL7704409A/xx not_active Application Discontinuation
- 1977-04-22 BE BE176944A patent/BE853874A/fr unknown
- 1977-04-22 FR FR7712273A patent/FR2348971A1/fr active Granted
- 1977-04-22 GB GB16870/77A patent/GB1570453A/en not_active Expired
- 1977-04-23 JP JP4727577A patent/JPS52151794A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2717782A1 (de) | 1977-11-03 |
| GB1570453A (en) | 1980-07-02 |
| AU2450477A (en) | 1978-10-26 |
| FR2348971B1 (fr) | 1980-12-26 |
| NL7704409A (nl) | 1977-10-25 |
| IT1080447B (it) | 1985-05-16 |
| CH629533A5 (de) | 1982-04-30 |
| SE7704689L (sv) | 1977-10-24 |
| DK178777A (da) | 1978-01-30 |
| CA1077870A (fr) | 1980-05-20 |
| FR2348971A1 (fr) | 1977-11-18 |
| US4082613A (en) | 1978-04-04 |
| JPS52151794A (en) | 1977-12-16 |
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