BE855481A - Hemoglobine encapsulee et procede pour la preparer - Google Patents

Hemoglobine encapsulee et procede pour la preparer

Info

Publication number
BE855481A
BE855481A BE178277A BE178277A BE855481A BE 855481 A BE855481 A BE 855481A BE 178277 A BE178277 A BE 178277A BE 178277 A BE178277 A BE 178277A BE 855481 A BE855481 A BE 855481A
Authority
BE
Belgium
Prior art keywords
preparing
encapsulated hemoglobin
hemoglobin
encapsulated
Prior art date
Application number
BE178277A
Other languages
English (en)
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of BE855481A publication Critical patent/BE855481A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BE178277A 1976-06-10 1977-06-07 Hemoglobine encapsulee et procede pour la preparer BE855481A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69490376A 1976-06-10 1976-06-10

Publications (1)

Publication Number Publication Date
BE855481A true BE855481A (fr) 1977-12-07

Family

ID=24790735

Family Applications (1)

Application Number Title Priority Date Filing Date
BE178277A BE855481A (fr) 1976-06-10 1977-06-07 Hemoglobine encapsulee et procede pour la preparer

Country Status (8)

Country Link
US (1) US4133874A (fr)
JP (1) JPS6026092B2 (fr)
BE (1) BE855481A (fr)
CA (1) CA1095444A (fr)
DE (1) DE2725696A1 (fr)
FR (1) FR2354095A1 (fr)
GB (1) GB1578776A (fr)
NL (1) NL7706417A (fr)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376059A (en) * 1980-04-11 1983-03-08 Exxon Research And Engineering Co. Process for preparing artificial red cells
US4390521A (en) * 1980-04-11 1983-06-28 Exxon Research And Engineering Co. Artificial red cells
US4469792A (en) * 1980-12-31 1984-09-04 Allied Corporation Blood gas calibration and control fluid utilizing stroma-free hemoglobin
EP0082877A1 (fr) * 1981-07-06 1983-07-06 Rush-Presbyterian-St.Luke's Medical Center Preparation d'erythrocytes synthetiques
US4558032A (en) * 1981-12-31 1985-12-10 Neomed Inc. Synthetic whole blood substitute and a method of making the same
US4547490A (en) * 1981-12-31 1985-10-15 Neomed, Inc. Synthetic whole blood and a method of making the same
US4425334A (en) * 1982-04-02 1984-01-10 The Regents Of The University Of California Functional oxygen transport system
US4612370A (en) * 1982-04-02 1986-09-16 The Regents Of The University Of California Lipid-saccharide reaction products
US4497829A (en) * 1982-07-27 1985-02-05 The University Of Pennsylvania Process for preparing perfluorochemical emulsion artificial blood
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
EP0223906A3 (fr) * 1982-10-29 1989-02-01 Synthetic Blood Corporation Sang entier synthétique à base de gélatine et son procédé de fabrication
US4530794A (en) * 1982-12-01 1985-07-23 Taiho Pharmaceutical Co., Ltd. Iron-tetraphenylporphine complex having phosphocholine group
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
GB8407557D0 (en) * 1984-03-23 1984-05-02 Hayward J A Polymeric lipsomes
FR2562421B1 (fr) * 1984-04-09 1989-02-17 Sandoz Sa Perfectionnements a la therapie par l'interleukine
US4853370A (en) * 1984-04-27 1989-08-01 Synthetic Blood Corporation Substitute for human blood and a method of making the same
US4738952A (en) * 1984-04-27 1988-04-19 Synthetic Blood Corporation Substitute for human blood and a method of making the same
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
JPS6137735A (ja) * 1984-07-31 1986-02-22 Terumo Corp ヘモグロビン含有リポソ−ムおよびその製造方法
US4737276A (en) * 1984-12-21 1988-04-12 E. I. Du Pont De Nemours And Company Apparatus for manufacturing liposomes
US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
JPS61155336A (ja) * 1984-12-28 1986-07-15 Terumo Corp 医用担体
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
CA1312009C (fr) * 1986-11-10 1992-12-29 Carl W. Rausch Substitut sanguin semi-synthetique extra pur
AU608304B2 (en) * 1987-02-27 1991-03-28 Terumo Kabushiki Kaisha Process for preparing liposome
JPS63211222A (ja) * 1987-02-27 1988-09-02 Terumo Corp リポソ−ムの製法
JPS63211230A (ja) * 1987-02-27 1988-09-02 Terumo Corp ヘモグロビン含有リポソ−ム
US4917951A (en) * 1987-07-28 1990-04-17 Micro-Pak, Inc. Lipid vesicles formed of surfactants and steroids
US5023086A (en) * 1987-03-13 1991-06-11 Micro-Pak, Inc. Encapsulated ionophore growth factors
US5628936A (en) * 1987-03-13 1997-05-13 Micro-Pak, Inc. Hybrid paucilamellar lipid vesicles
US5000960A (en) * 1987-03-13 1991-03-19 Micro-Pak, Inc. Protein coupling to lipid vesicles
US5234767A (en) * 1987-03-13 1993-08-10 Micro-Pak, Inc. Hybrid paucilamellar lipid vesicles
US4855090A (en) * 1987-03-13 1989-08-08 Micro-Pak, Inc. Method of producing high aqueous volume multilamellar vesicles
US4942038A (en) * 1987-03-13 1990-07-17 Micro Vesicular Systems, Inc. Encapsulated humectant
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles
US4853228A (en) * 1987-07-28 1989-08-01 Micro-Pak, Inc. Method of manufacturing unilamellar lipid vesicles
JPH01180245A (ja) * 1988-01-12 1989-07-18 Terumo Corp リポソーム
US5019392A (en) * 1988-03-03 1991-05-28 Micro-Pak, Inc. Encapsulation of parasiticides
US5160669A (en) * 1988-03-03 1992-11-03 Micro Vesicular Systems, Inc. Method of making oil filled paucilamellar lipid vesicles
US5019174A (en) * 1988-03-03 1991-05-28 Micro Vesicular Systems, Inc. Removing oil from surfaces with liposomal cleaner
US5104736A (en) * 1988-03-03 1992-04-14 Micro-Pak, Inc. Reinforced paucilamellar lipid vesicles
JPH0720857B2 (ja) * 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
JPH0661459B2 (ja) * 1988-09-26 1994-08-17 テルモ株式会社 リポソームおよびその製法
JPH02121932A (ja) * 1988-10-29 1990-05-09 Res Inst For Prod Dev ヘモグロビン含有リポソーム、その製造方法および該製造方法用の原液
FR2641463B1 (fr) * 1989-01-09 1991-03-08 Sederma Sa Preparations cosmetiques destinees a l'oxygenation de la peau
US4935171A (en) * 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances
US5015483A (en) * 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5284663A (en) * 1991-07-23 1994-02-08 Temple University Salt film encapsulated perfluorocarbons
EP0615747B1 (fr) * 1993-03-18 1999-09-29 Terumo Kabushiki Kaisha Liposome encapsulant de l'hémoglobine et procédé pour sa préparation
US5674528A (en) * 1994-06-15 1997-10-07 Terumo Kabushiki Kaisha Hemoglobin-encapsulated liposome
US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion
CA2234957C (fr) * 1995-10-17 2006-12-19 Inge B. Henriksen Administration de medicaments insolubles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
ATE302019T1 (de) * 1997-02-28 2005-09-15 Univ California Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen
US5814601A (en) * 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
US7687272B1 (en) 1998-01-12 2010-03-30 Henry Buchwald Method and apparatus for determining blood oxygen transport
US6037181A (en) * 1998-01-12 2000-03-14 Buchwald; Henry Method and apparatus for determining blood oxygen transport
ATE241363T1 (de) * 1998-02-11 2003-06-15 Rtp Pharma Corp Ungesättigte fettsäure und steroide enthaltende kombinationspräparate zur behandlung von entzündungen
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
EP1079808B1 (fr) 1998-05-29 2004-02-11 Skyepharma Canada Inc. Compositions de microparticules a protection thermique et procede de sterilisation a la vapeur apres conditionnement
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
US7939105B2 (en) 1998-11-20 2011-05-10 Jagotec Ag Process for preparing a rapidly dispersing solid drug dosage form
US6806091B1 (en) 1999-01-12 2004-10-19 Henry Buchwald Method and apparatus for determining blood oxygen transport
JP2003509453A (ja) * 1999-09-21 2003-03-11 アールティーピー・ファーマ・インコーポレーテッド 生物学的に活性な物質の、表面改質された粒状組成物
US6500809B1 (en) 1999-11-12 2002-12-31 Neuron Therapeutics, Inc. Hyperoncotic artificial cerebrospinal fluid and method of treating neural tissue edema therewith
US6710038B1 (en) 1999-12-14 2004-03-23 Kibun Food Chemifa Co., Ltd. Emulsification method using propylene glycol hyaluronate
JP5102423B2 (ja) 2000-04-20 2012-12-19 オバン・エナジー・リミテッド 改善された水不溶性薬剤粒子の処理
JP4969761B2 (ja) 2000-08-31 2012-07-04 オバン・エナジー・リミテッド 所望粒度を持つ固体基材の小粒子および第一材料の小粒状物を含む相乗作用性混合物を製造する方法
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
NZ525231A (en) * 2000-09-20 2004-08-27 Skyepharma Canada Inc Phospholipid stabilised feno-fibrate microparticles for pharmaceutical use
US6534088B2 (en) * 2001-02-22 2003-03-18 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
HUP0101713A2 (hu) * 2001-04-27 2003-02-28 István Horváth Eljárás mesterséges vér előállítására liofilezett vagy friss vérből nyerhető hemoglobin felhasználásával
US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050164915A1 (en) * 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050287125A1 (en) * 2002-05-22 2005-12-29 Medtronic, Inc. Cell delivery fluid for prevention of cell settling in delivery system
JP3912206B2 (ja) * 2002-07-05 2007-05-09 株式会社日立製作所 筒内直接燃料噴射装置用燃料ポンプ
HU226519B1 (en) * 2002-11-26 2009-03-30 Istvan Dr Horvath Artificial blood made of hemoglobin encapsulated in membrane
CU23313A1 (es) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
JP2004307404A (ja) * 2003-04-08 2004-11-04 Nipro Corp 人工酸素運搬体を含む医薬組成物
DE102008043751B4 (de) * 2008-11-14 2013-09-26 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur Herstellung von großen Vesikeln aus selbstorganisierenden, membranbildenden Molekülen
WO2014078052A1 (fr) * 2012-11-15 2014-05-22 Bio-Rad Laboratories, Inc. Contrôles de qualité d'hémoglobine cellulaire a1c

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2236909A1 (de) * 1972-07-27 1974-02-07 Fresenius Chem Pharm Ind Blutersatzfluessigkeit
DE2248475C3 (de) * 1972-10-03 1978-09-28 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Gewinnung von hepatitissicheren, lagerungsstabilen und infundierbaren Hämoglobinlösungen
US3887698A (en) * 1973-03-12 1975-06-03 Univ Leland Stanford Junior Sacs with epitopic sites on walls enclosing stable free radicals
CH588887A5 (fr) * 1974-07-19 1977-06-15 Battelle Memorial Institute

Also Published As

Publication number Publication date
GB1578776A (en) 1980-11-12
DE2725696A1 (de) 1977-12-22
JPS52151718A (en) 1977-12-16
CA1095444A (fr) 1981-02-10
NL7706417A (nl) 1977-12-13
FR2354095A1 (fr) 1978-01-06
US4133874A (en) 1979-01-09
FR2354095B1 (fr) 1980-04-25
JPS6026092B2 (ja) 1985-06-21

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: UNIVERSITY OF ILLINOIS FOUNDATION

Effective date: 19920630