BE856682A - DERIVES D'ACIDES 5-(2-FUROYL)-, 5-(2-THENOYL)-, 5-(3-FUROYL)- ET 5-(3-THENOYL)-1,2-DIHYDRO-3H-PYRROLE (1,2-a) PYRROLE-1-CARBOXYLIQUES - Google Patents
DERIVES D'ACIDES 5-(2-FUROYL)-, 5-(2-THENOYL)-, 5-(3-FUROYL)- ET 5-(3-THENOYL)-1,2-DIHYDRO-3H-PYRROLE (1,2-a) PYRROLE-1-CARBOXYLIQUESInfo
- Publication number
- BE856682A BE856682A BE179237A BE179237A BE856682A BE 856682 A BE856682 A BE 856682A BE 179237 A BE179237 A BE 179237A BE 179237 A BE179237 A BE 179237A BE 856682 A BE856682 A BE 856682A
- Authority
- BE
- Belgium
- Prior art keywords
- thenoyl
- furoyl
- pyrrole
- carboxylics
- dihydro
- Prior art date
Links
- XBDDRFYWURCJTD-UHFFFAOYSA-N 2,3-dihydro-1h-pyrrol-5-yl(thiophen-3-yl)methanone Chemical compound C1=CSC=C1C(=O)C1=CCCN1 XBDDRFYWURCJTD-UHFFFAOYSA-N 0.000 title 1
- -1 3-FUROYL Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70485776A | 1976-07-14 | 1976-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE856682A true BE856682A (fr) | 1978-01-11 |
Family
ID=24831134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE179237A BE856682A (fr) | 1976-07-14 | 1977-07-11 | DERIVES D'ACIDES 5-(2-FUROYL)-, 5-(2-THENOYL)-, 5-(3-FUROYL)- ET 5-(3-THENOYL)-1,2-DIHYDRO-3H-PYRROLE (1,2-a) PYRROLE-1-CARBOXYLIQUES |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4087539A (fr) |
| AT (1) | AT363464B (fr) |
| BE (1) | BE856682A (fr) |
| ZA (1) | ZA774239B (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4140698A (en) * | 1977-07-25 | 1979-02-20 | Syntex (Usa) Inc. | 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles |
| US4232038A (en) * | 1979-08-31 | 1980-11-04 | Syntex (U.S.A.) Inc. | 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids |
| US4410534A (en) * | 1979-12-26 | 1983-10-18 | Syntex (U.S.A.) Inc. | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors |
| US4344943A (en) * | 1980-06-09 | 1982-08-17 | Syntex (U.S.A.) Inc. | 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof |
| US4347185A (en) * | 1980-10-20 | 1982-08-31 | Syntex (U.S.A.) Inc. | Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids |
| US4353829A (en) * | 1980-11-21 | 1982-10-12 | Syntex (U.S.A.) Inc. | Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters |
| US4454326A (en) * | 1981-06-11 | 1984-06-12 | Syntex (U.S.A.) Inc. | 5-Aroyl 6-chloro or 6-bromo 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1,1-di-carboxylates |
| US4434175A (en) | 1981-08-10 | 1984-02-28 | Merck & Co., Inc. | Nonsteroidal compounds as anti-inflammatory and analgesic agents |
| WO1983001382A1 (fr) * | 1981-10-13 | 1983-04-28 | Mroszczak, Edward | Promedicaments de thioesters menageant le systeme gastrointestinal |
| US4457941A (en) * | 1982-03-22 | 1984-07-03 | Syntex (U.S.A.) Inc. | Use of pyrrolo-pyrrole in treating microvascular diseases associated with diabetes |
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| US4533671A (en) * | 1982-10-08 | 1985-08-06 | Merck & Co., Inc. | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2-alkanoic or carboxylic acids and analogs as anti-inflammatory and analgesic agents |
| US4536512A (en) * | 1982-10-08 | 1985-08-20 | Merck & Co., Inc. | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2,3-dihydro-1H-pyrrolizine-1-alkanoic or carboxylic acids and use thereof as anti-inflammatory and analgesic agents |
| EP0117675B1 (fr) * | 1983-02-19 | 1986-07-23 | Beecham Group Plc | Dérivés d'acide benzofuranne- et benzothiophène carboxylique |
| US4988822A (en) * | 1986-05-29 | 1991-01-29 | Syntex (U.S.A.) Inc. | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates |
| US4873340A (en) * | 1986-05-29 | 1989-10-10 | Syntex (U.S.A.) Inc. | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates |
| US4874872A (en) * | 1987-01-14 | 1989-10-17 | Syntex (U.S.A.) Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates |
| US4835288A (en) * | 1987-01-14 | 1989-05-30 | Syntex Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates |
| US4937368A (en) * | 1987-01-14 | 1990-06-26 | Syntex (U.S.A.) Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates |
| US4874871A (en) * | 1987-03-25 | 1989-10-17 | Syntex (U.S.A.) Inc. | Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds |
| US5414011A (en) * | 1987-09-11 | 1995-05-09 | Syntex (U.S.A.) Inc. | Preservative system for ophthalmic formulations |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| WO1995001767A1 (fr) * | 1993-07-08 | 1995-01-19 | Cygnus Therapeutic Systems | Systeme d'apports transdermique par matrice monolithe |
| US5621115A (en) * | 1996-02-21 | 1997-04-15 | Ohmeda Pharmaceutical Products Division Inc. | Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrrole-1-carboxylic acids |
| US6191285B1 (en) | 1997-07-03 | 2001-02-20 | Abbott Laboratories | Process for the preparation of ketorolac tromethamine |
| BRPI0710527B8 (pt) | 2006-04-04 | 2021-05-25 | Fibrogen Inc | compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende |
| JP4802243B2 (ja) | 2006-06-30 | 2011-10-26 | 大塚化学株式会社 | 電解液用添加剤及び電解液 |
-
1977
- 1977-02-23 US US05/771,283 patent/US4087539A/en not_active Expired - Lifetime
- 1977-07-11 BE BE179237A patent/BE856682A/fr not_active IP Right Cessation
- 1977-07-14 AT AT0508977A patent/AT363464B/de not_active IP Right Cessation
- 1977-07-14 ZA ZA00774239A patent/ZA774239B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT363464B (de) | 1981-08-10 |
| ATA508977A (de) | 1981-01-15 |
| US4087539A (en) | 1978-05-02 |
| ZA774239B (en) | 1979-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: SYNTEX (U.S.A.) INC. Effective date: 19900731 |