BE882152A - Phenylmorphanes, intermediaires et procedes de synthese, et leur utilisation therapeutique - Google Patents

Phenylmorphanes, intermediaires et procedes de synthese, et leur utilisation therapeutique

Info

Publication number
BE882152A
BE882152A BE1/9743A BE1009743A BE882152A BE 882152 A BE882152 A BE 882152A BE 1/9743 A BE1/9743 A BE 1/9743A BE 1009743 A BE1009743 A BE 1009743A BE 882152 A BE882152 A BE 882152A
Authority
BE
Belgium
Prior art keywords
phenylmorphanes
intermediates
synthesis
methods
therapeutic use
Prior art date
Application number
BE1/9743A
Other languages
English (en)
Inventor
D M Zimmerman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE882152A publication Critical patent/BE882152A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BE1/9743A 1979-03-12 1980-03-10 Phenylmorphanes, intermediaires et procedes de synthese, et leur utilisation therapeutique BE882152A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1952779A 1979-03-12 1979-03-12

Publications (1)

Publication Number Publication Date
BE882152A true BE882152A (fr) 1980-09-10

Family

ID=21793680

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/9743A BE882152A (fr) 1979-03-12 1980-03-10 Phenylmorphanes, intermediaires et procedes de synthese, et leur utilisation therapeutique

Country Status (11)

Country Link
EP (2) EP0018077A3 (fr)
JP (1) JPS55124768A (fr)
KR (1) KR830001900A (fr)
BE (1) BE882152A (fr)
CA (1) CA1148150A (fr)
FR (1) FR2451368A1 (fr)
GB (2) GB2045248B (fr)
HU (1) HU179836B (fr)
IL (1) IL59553A0 (fr)
IT (1) IT1129740B (fr)
LU (1) LU82235A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0652811B2 (ja) * 1984-07-04 1994-07-06 松下電器産業株式会社 高電圧発生装置
US5087214A (en) * 1991-05-21 1992-02-11 United Technologies Automotive, Inc. Battery terminal connector
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
JP4498602B2 (ja) * 1998-03-10 2010-07-07 リサーチ・トライアングル・インスティチュート 新規なオピエート化合物、その調製法及び使用法
US6608080B1 (en) 1999-02-18 2003-08-19 Hisamitsu Pharmaceutical Co., Ltd. Morphan derivatives or salts thereof and medicinal compositions containing the same
TW200306189A (en) * 2002-03-21 2003-11-16 Merz Pharma Gmbh & Co Kgaa Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206937A1 (es) * 1974-09-06 1976-08-31 Lilly Co Eli Procedimiento para preparar compuestos de 1-sustituido-4-alquil-4-fenil-piperidina

Also Published As

Publication number Publication date
CA1148150A (fr) 1983-06-14
GB2045248A (en) 1980-10-29
GB2045248B (en) 1983-05-05
EP0059989A1 (fr) 1982-09-15
JPS55124768A (en) 1980-09-26
GB2111976A (en) 1983-07-13
IT1129740B (it) 1986-06-11
LU82235A1 (fr) 1980-06-06
GB2111976B (en) 1983-11-09
EP0018077A3 (en) 1980-11-26
HU179836B (en) 1982-12-28
IT8020473A0 (it) 1980-03-10
KR830001900A (ko) 1983-05-19
IL59553A0 (en) 1980-06-30
FR2451368B1 (fr) 1983-03-18
FR2451368A1 (fr) 1980-10-10
EP0018077A2 (fr) 1980-10-29

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19850310