BE886486A - Forme pharmaceutique "gel" contenant l'acide 2-(3-benzoyl-phenyl)-propionique et son utilisation en therapeutique pour un usage local - Google Patents

Forme pharmaceutique "gel" contenant l'acide 2-(3-benzoyl-phenyl)-propionique et son utilisation en therapeutique pour un usage local Download PDF

Info

Publication number: BE886486A
Authority: BE; Belgium
Prior art keywords: gel; propionic acid; pharmaceutical form; local; therapeutics
Prior art date: 1979-12-05

Application number

BE0/203034A

Other languages

English (en)

French (fr)

Original Assignee

Menarini Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-12-05

Filing date

1980-12-04

Publication date

1981-04-01

1980-12-04 Application filed by Menarini Sas filed Critical Menarini Sas

1981-04-01 Publication of BE886486A publication Critical patent/BE886486A/fr

Links

DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 title description 13
239000003814 drug Substances 0.000 title description 2
239000000203 mixture Substances 0.000 claims description 7
230000002757 inflammatory effect Effects 0.000 claims description 3
238000000034 method Methods 0.000 claims description 3
238000002560 therapeutic procedure Methods 0.000 claims description 3
208000011580 syndromic disease Diseases 0.000 claims description 2
229960000991 ketoprofen Drugs 0.000 description 6
239000002674 ointment Substances 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
230000004899 motility Effects 0.000 description 3
239000000243 solution Substances 0.000 description 3
239000000725 suspension Substances 0.000 description 3
206010003246 arthritis Diseases 0.000 description 2
239000006071 cream Substances 0.000 description 2
210000001503 joint Anatomy 0.000 description 2
210000003041 ligament Anatomy 0.000 description 2
210000003205 muscle Anatomy 0.000 description 2
238000002559 palpation Methods 0.000 description 2
238000004062 sedimentation Methods 0.000 description 2
210000002435 tendon Anatomy 0.000 description 2
230000001225 therapeutic effect Effects 0.000 description 2
230000000699 topical effect Effects 0.000 description 2
MFSJSVNVUDQHLV-UHFFFAOYSA-N 2-(3-benzoylphenyl)propanoic acid Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1.OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 MFSJSVNVUDQHLV-UHFFFAOYSA-N 0.000 description 1
206010061728 Bone lesion Diseases 0.000 description 1
102000001554 Hemoglobins Human genes 0.000 description 1
108010054147 Hemoglobins Proteins 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
206010034464 Periarthritis Diseases 0.000 description 1
102000003929 Transaminases Human genes 0.000 description 1
108090000340 Transaminases Proteins 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
230000001760 anti-analgesic effect Effects 0.000 description 1
230000003110 anti-inflammatory effect Effects 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000008280 blood Substances 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
210000000416 exudates and transudate Anatomy 0.000 description 1
238000005534 hematocrit Methods 0.000 description 1
230000002489 hematologic effect Effects 0.000 description 1
230000004968 inflammatory condition Effects 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
210000003127 knee Anatomy 0.000 description 1
230000003902 lesion Effects 0.000 description 1
210000000265 leukocyte Anatomy 0.000 description 1
230000003387 muscular Effects 0.000 description 1
230000001354 painful effect Effects 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
231100000444 skin lesion Toxicity 0.000 description 1
206010040882 skin lesion Diseases 0.000 description 1
239000002904 solvent Substances 0.000 description 1
230000002269 spontaneous effect Effects 0.000 description 1
230000000472 traumatic effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BE0/203034A 1979-12-05 1980-12-04 Forme pharmaceutique "gel" contenant l'acide 2-(3-benzoyl-phenyl)-propionique et son utilisation en therapeutique pour un usage local BE886486A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT09616/79A IT1124398B (it)	1979-12-05	1979-12-05	Utilizzazione della forma farmaceutica gel contenente acido 23 benzoilfenil propionico impiegabile in terapia per uso topico

Publications (1)

Publication Number	Publication Date
BE886486A true BE886486A (fr)	1981-04-01

Family

ID=11132713

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE0/203034A BE886486A (fr)	1979-12-05	1980-12-04	Forme pharmaceutique "gel" contenant l'acide 2-(3-benzoyl-phenyl)-propionique et son utilisation en therapeutique pour un usage local

Country Status (3)

Country	Link
BE (1)	BE886486A (es)
ES (1)	ES497415A0 (es)
IT (1)	IT1124398B (es)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2482456A1 (fr) *	1980-05-14	1981-11-20	Hisamitsu Pharmaceutical Co	Composition en gel, anti-inflammatoire et analgesique, a base de ketoprofene et/ou de flurbiprofene
EP0127840A1 (en) *	1983-06-01	1984-12-12	Lederle (Japan) Ltd.	Antiinflammatory analgesic gelled ointments
FR2561917A1 (fr) *	1984-04-03	1985-10-04	Hokuriku Pharmaceutical	Creme anti-inflammatoire et antipyretique
EP0252033A3 (en) *	1986-07-02	1988-03-30	A. Menarini S.A.S.	Utilization of the "gel" pharmaceutical form containing n-(2.6-dichloro-m-tolil)-anthranilic acid (mechlophenamic acid) utilizable in therapy for topical usage
WO1998055113A1 (en) *	1997-06-04	1998-12-10	Laboratorios Menarini S.A.	Semisolid pharmaceutical formulation containing dexketoprofen trometamol
FR2797766A1 (fr) *	1999-08-27	2001-03-02	Menarini France	Nouvelles formes topiques a consistance pateuse sous forme d'un gel distribue en doses

1979
- 1979-12-05 IT IT09616/79A patent/IT1124398B/it active
1980
- 1980-12-03 ES ES497415A patent/ES497415A0/es active Granted
- 1980-12-04 BE BE0/203034A patent/BE886486A/fr not_active IP Right Cessation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2482456A1 (fr) *	1980-05-14	1981-11-20	Hisamitsu Pharmaceutical Co	Composition en gel, anti-inflammatoire et analgesique, a base de ketoprofene et/ou de flurbiprofene
EP0127840A1 (en) *	1983-06-01	1984-12-12	Lederle (Japan) Ltd.	Antiinflammatory analgesic gelled ointments
FR2561917A1 (fr) *	1984-04-03	1985-10-04	Hokuriku Pharmaceutical	Creme anti-inflammatoire et antipyretique
EP0252033A3 (en) *	1986-07-02	1988-03-30	A. Menarini S.A.S.	Utilization of the "gel" pharmaceutical form containing n-(2.6-dichloro-m-tolil)-anthranilic acid (mechlophenamic acid) utilizable in therapy for topical usage
WO1998055113A1 (en) *	1997-06-04	1998-12-10	Laboratorios Menarini S.A.	Semisolid pharmaceutical formulation containing dexketoprofen trometamol
AU728442B2 (en) *	1997-06-04	2001-01-11	Laboratorios Menarini S.A.	Semisolid pharmaceutical formulation containing dexketoprofen trometamol
FR2797766A1 (fr) *	1999-08-27	2001-03-02	Menarini France	Nouvelles formes topiques a consistance pateuse sous forme d'un gel distribue en doses

Also Published As

Publication number	Publication date
IT1124398B (it)	1986-05-07
ES8200322A1 (es)	1981-11-01
ES497415A0 (es)	1981-11-01
IT7909616A0 (it)	1979-12-05

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Legal Events

Date

Code

Title

Description

2000-01-01

RE20

Patent expired

Owner name: A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L

Effective date: 20001204