BE896291A - 3,4-DIAMINO-1,2,5-THIADIAZOLES SUBSTITUTED HAVING HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY - Google Patents

3,4-DIAMINO-1,2,5-THIADIAZOLES SUBSTITUTED HAVING HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY

Info

Publication number: BE896291A
Authority: BE; Belgium
Prior art keywords: histamine; diamino; receptor antagonist; antagonist activity; thiadiazoles
Prior art date: 1982-03-29

Application number

BE0/210417A

Other languages

French (fr)

Inventor

R R Crenshaw

A A Algieri

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-03-29

Filing date

1983-03-28

Publication date

1983-09-28

1983-03-28 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1983-09-28 Publication of BE896291A publication Critical patent/BE896291A/en

Links

229940122957 Histamine H2 receptor antagonist Drugs 0.000 title 1
239000003485 histamine H2 receptor antagonist Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Furan Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pyrrole Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BE0/210417A 1982-03-29 1983-03-28 3,4-DIAMINO-1,2,5-THIADIAZOLES SUBSTITUTED HAVING HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY BE896291A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36320782A	1982-03-29	1982-03-29

Publications (1)

Publication Number	Publication Date
BE896291A true BE896291A (en)	1983-09-28

Family

ID=23429274

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE0/210417A BE896291A (en)	1982-03-29	1983-03-28	3,4-DIAMINO-1,2,5-THIADIAZOLES SUBSTITUTED HAVING HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY

Country Status (30)

Country	Link
JP (2)	JPS58180477A (en)
KR (1)	KR880002209B1 (en)
AT (1)	AT386599B (en)
AU (2)	AU557577B2 (en)
BE (1)	BE896291A (en)
CH (2)	CH655111A5 (en)
CS (2)	CS250240B2 (en)
DD (2)	DD210909A5 (en)
DE (1)	DE3311281A1 (en)
DK (2)	DK166677B1 (en)
ES (3)	ES8404683A1 (en)
FR (2)	FR2542741B1 (en)
GB (2)	GB2117769B (en)
GR (1)	GR78524B (en)
HU (2)	HU188742B (en)
IE (1)	IE55596B1 (en)
IL (1)	IL68259A0 (en)
IT (1)	IT1164633B (en)
LU (1)	LU84716A1 (en)
MY (1)	MY8700942A (en)
NL (1)	NL8301063A (en)
NO (1)	NO163055C (en)
NZ (1)	NZ203726A (en)
OA (1)	OA07356A (en)
PT (1)	PT76459B (en)
SE (2)	SE461040B (en)
SU (2)	SU1419518A3 (en)
YU (1)	YU44849B (en)
ZA (1)	ZA832154B (en)
ZW (1)	ZW7683A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2222083A (en) *	1982-12-14	1984-06-21	Smith Kline & French Laboratories Limited	Pyridine derivatives
US4593039A (en) *	1984-04-02	1986-06-03	Merck & Co., Inc.	1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
US4644006A (en) *	1984-06-22	1987-02-17	Bristol-Myers Company	Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
JPH0622828B2 (en) *	1986-06-30	1994-03-30	フアナツク株式会社	Direct pressure type mold clamping mechanism
WO2022034121A1 (en)	2020-08-11	2022-02-17	Université De Strasbourg	H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3018289A (en) *	1960-02-10	1962-01-23	Wyandotte Chemicals Corp	Process for preparing oxamidines
GB1595291A (en) *	1976-09-21	1981-08-12	Smith Kline French Lab	Pyrimidone and thiopyrimidone derivatives
DK160611C (en) *	1979-09-04	1991-09-16	Bristol Myers Squibb Co	ANALOGY PROCEDURE FOR PREPARING 3,4-DISUBSTITUTED 1,2,5-THIADIAZOL-1-OXIDES AND -1,1-DIOXIDES
EP0040696B1 (en) *	1980-04-30	1986-08-27	Merck & Co. Inc.	Aminothiadiazoles as gastric secretion inhibitors
AU2222083A (en) *	1982-12-14	1984-06-21	Smith Kline & French Laboratories Limited	Pyridine derivatives

1983
- 1983-03-25 ES ES520982A patent/ES8404683A1/en not_active Expired
- 1983-03-25 NL NL8301063A patent/NL8301063A/en not_active Application Discontinuation
- 1983-03-25 ZW ZW76/83A patent/ZW7683A1/en unknown
- 1983-03-25 ZA ZA832154A patent/ZA832154B/en unknown
- 1983-03-25 FR FR838304934A patent/FR2542741B1/en not_active Expired
- 1983-03-28 GB GB08308518A patent/GB2117769B/en not_active Expired
- 1983-03-28 PT PT76459A patent/PT76459B/en not_active IP Right Cessation
- 1983-03-28 SE SE8301725A patent/SE461040B/en not_active IP Right Cessation
- 1983-03-28 IL IL68259A patent/IL68259A0/en not_active IP Right Cessation
- 1983-03-28 IT IT48005/83A patent/IT1164633B/en active
- 1983-03-28 GR GR70903A patent/GR78524B/el unknown
- 1983-03-28 DE DE19833311281 patent/DE3311281A1/en not_active Withdrawn
- 1983-03-28 IE IE686/83A patent/IE55596B1/en not_active IP Right Cessation
- 1983-03-28 SU SU833568849A patent/SU1419518A3/en active
- 1983-03-28 HU HU831040A patent/HU188742B/en not_active IP Right Cessation
- 1983-03-28 BE BE0/210417A patent/BE896291A/en not_active IP Right Cessation
- 1983-03-28 AU AU12907/83A patent/AU557577B2/en not_active Ceased
- 1983-03-28 HU HU854071A patent/HU196386B/en not_active IP Right Cessation
- 1983-03-28 DK DK141383A patent/DK166677B1/en not_active IP Right Cessation
- 1983-03-28 LU LU84716A patent/LU84716A1/en unknown
- 1983-03-28 NO NO831100A patent/NO163055C/en unknown
- 1983-03-28 NZ NZ203726A patent/NZ203726A/en unknown
- 1983-03-29 KR KR1019830001283A patent/KR880002209B1/en not_active Expired
- 1983-03-29 JP JP58051740A patent/JPS58180477A/en active Granted
- 1983-03-29 OA OA57955A patent/OA07356A/en unknown
- 1983-03-29 DD DD83249300A patent/DD210909A5/en not_active IP Right Cessation
- 1983-03-29 AT AT0111083A patent/AT386599B/en not_active IP Right Cessation
- 1983-03-29 YU YU744/83A patent/YU44849B/en unknown
- 1983-03-29 CH CH1749/83A patent/CH655111A5/en not_active IP Right Cessation
- 1983-03-29 CH CH575/86A patent/CH660880A5/en not_active IP Right Cessation
- 1983-03-29 DD DD83260707A patent/DD219768A5/en not_active IP Right Cessation
- 1983-03-29 CS CS841958A patent/CS250240B2/en unknown
- 1983-03-29 CS CS832191A patent/CS250229B2/en unknown
- 1983-11-30 ES ES527686A patent/ES8505978A1/en not_active Expired
- 1983-11-30 ES ES527685A patent/ES527685A0/en active Granted
1984
- 1984-06-08 SU SU843750493A patent/SU1355123A3/en active
- 1984-12-31 GB GB08432809A patent/GB2149406B/en not_active Expired
1986
- 1986-09-30 AU AU63272/86A patent/AU586037B2/en not_active Ceased
1987
- 1987-05-22 FR FR878707197A patent/FR2597867B1/en not_active Expired
- 1987-11-25 SE SE8704689A patent/SE464302B/en not_active IP Right Cessation
- 1987-12-30 MY MY942/87A patent/MY8700942A/en unknown
1992
- 1992-06-18 DK DK92811A patent/DK81192D0/en not_active Application Discontinuation
1993
- 1993-04-16 JP JP5124585A patent/JPH06135925A/en active Pending

Also Published As

Publication number	Publication date
DD219768A5 (en)	1985-03-13
NO831100L (en)	1983-09-30
SE8301725L (en)	1983-11-25
KR880002209B1 (en)	1988-10-18
PT76459A (en)	1983-04-01
ZA832154B (en)	1983-12-28
DK166677B1 (en)	1993-06-28
ES527686A0 (en)	1985-06-16
HU188742B (en)	1986-05-28
SE8301725D0 (en)	1983-03-28
GR78524B (en)	1984-09-27
ES8505978A1 (en)	1985-06-16
SU1419518A3 (en)	1988-08-23
CS250229B2 (en)	1987-04-16
SE464302B (en)	1991-04-08
NO163055B (en)	1989-12-18
CH655111A5 (en)	1986-03-27
ES520982A0 (en)	1984-05-16
SE461040B (en)	1989-12-18
PT76459B (en)	1986-03-11
DK81192A (en)	1992-06-18
GB8308518D0 (en)	1983-05-05
AU6327286A (en)	1987-01-08
YU44849B (en)	1991-04-30
JPH06135925A (en)	1994-05-17
GB8432809D0 (en)	1985-02-06
IL68259A0 (en)	1983-06-15
YU74483A (en)	1986-02-28
LU84716A1 (en)	1983-12-05
ES8505977A1 (en)	1985-06-16
AU586037B2 (en)	1989-06-29
ATA111083A (en)	1988-02-15
FR2597867A1 (en)	1987-10-30
GB2117769A (en)	1983-10-19
ZW7683A1 (en)	1984-01-04
CS250240B2 (en)	1987-04-16
FR2542741B1 (en)	1989-12-08
GB2117769B (en)	1985-08-29
SU1355123A3 (en)	1987-11-23
SE8704689D0 (en)	1987-11-25
SE8704689L (en)	1987-11-25
HU196386B (en)	1988-11-28
NZ203726A (en)	1986-05-09
AT386599B (en)	1988-09-12
ES8404683A1 (en)	1984-05-16
DE3311281A1 (en)	1983-11-24
JPH0568472B2 (en)	1993-09-29
GB2149406B (en)	1986-01-02
NL8301063A (en)	1983-10-17
GB2149406A (en)	1985-06-12
DK141383D0 (en)	1983-03-28
ES527685A0 (en)	1985-06-16
IT1164633B (en)	1987-04-15
OA07356A (en)	1984-08-31
IE55596B1 (en)	1990-11-21
FR2597867B1 (en)	1989-12-08
IT8348005A0 (en)	1983-03-28
CH660880A5 (en)	1987-05-29
IE830686L (en)	1983-09-29
JPS58180477A (en)	1983-10-21
DK81192D0 (en)	1992-06-18
NO163055C (en)	1990-03-28
AU1290783A (en)	1983-10-06
AU557577B2 (en)	1986-12-24
KR840004095A (en)	1984-10-06
DD210909A5 (en)	1984-06-27
DK141383A (en)	1983-09-30
MY8700942A (en)	1987-12-31
FR2542741A1 (en)	1984-09-21

Legal Events

Date

Code

Title

Description

1995-09-30

RE

Patent lapsed

Owner name: BRISTOL-MYERS CY

Effective date: 19950331

Publication	Publication Date	Title
ATE52495T1 (en)	1990-05-15	2-(2'-NITROBENZOYL)-1,3-CYCLOHEXANDIONES.
ATE40361T1 (en)	1989-02-15	2,2'-IMINOBISAETHANOL DERIVATIVES.
TR22585A (en)	1987-12-07	SOME 2- (2'-ALKILBENZOIL) -1,3-SIKLOHEKSANDIONS
SU1179924A3 (en)	1985-09-15	"CПOCOБ ПОЛУЧEHИЯ ПЛИЗЗДХЫX ИМИДАЗОЛА ИЛИ ИТУТОМОО, КЛИКИКОКОВО-АДДИТИХЫЫЛ"
FI820856L (en)	1982-09-17	2-PHENOXIALKYL-1,2,4-TRIAZOL-3-ON ANTIDEPRESSIVER
FR2569144B1 (en)	1989-09-08	DEVICE FOR ADJUSTING A SUSPENSION
FR2561595B1 (en)	1990-02-09	ADJUSTING DEVICE FOR SEAT
ES265752Y (en)	1983-07-01	"SEAT BELT ARRANGEMENT".
DE3475713D1 (en)	1989-01-26	3, 3 ", 4" TRI-O-ACYL SPIRAMYCIN I
FR2542741B1 (en)	1989-12-08	3,4-DIAMINO-1,2,5-THIADIAZOLES SUBSTITUTED HAVING HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY
FI845095A7 (en)	1984-12-21	Aminoimidazolone derivatives as histamine H2 antagonists.
FI863349L (en)	1986-08-19	DISPERSING AGENTS SALTS.
FR2566406B1 (en)	1988-01-29	SUBSTITUTED 3,4-DIAMINO-1,2,5-THIADIAZOLES WITH HISTAMINE H2 RECEPTOR ANTAGONIST ACTIVITY
IT8422192A0 (en)	1984-08-02	PART PROTECTED FROM WEAR.
FI822999A0 (en)	1982-08-30	3'-SUBSTITUTE 5 '- (2-AMINO-4-PYRIDYL) -1', 2 ', 4'-TRIAZOLER
FI861041A7 (en)	1986-03-13	FIBERDUK ERHAOLEN'S GENOM IN-SITU FIBERBILDNING.
IT8422744A1 (en)	1986-03-20	4 (3H) -PYRIMIDONS 2,5-SUBSTITUTED HAVING ACTIVITIES! ANTAGONIST OF HISTAMINE H2 RECEPTORS
ES266710Y (en)	1983-10-16	"BUCKET FEEDER".
ES264760Y (en)	1983-05-16	"BALIZATION MILESTONE".
ES267903Y (en)	1984-11-01	"COPYING TOOL".
ES265398Y (en)	1983-07-01	DETACHABLE HINGE.
ES264448Y (en)	1985-12-01	"IMPROVED ANTI-THEFT".
IT8304829A0 (en)	1983-07-22	ADVANCE MACHINE FOR THE CONSTRUCTION OF TUNNELS.
ES262782Y (en)	1983-05-01	"IMPROVED MOUSE PAD".
IT8319120V0 (en)	1983-08-09	WRITING AT 15 ', AT 30', AT 45 '