BE898873A - Nouveaux derives de l'acide lysergique, leur preparation et leur utilisation comme medicaments - Google Patents
Nouveaux derives de l'acide lysergique, leur preparation et leur utilisation comme medicamentsInfo
- Publication number
- BE898873A BE898873A BE1/10956A BE1010956A BE898873A BE 898873 A BE898873 A BE 898873A BE 1/10956 A BE1/10956 A BE 1/10956A BE 1010956 A BE1010956 A BE 1010956A BE 898873 A BE898873 A BE 898873A
- Authority
- BE
- Belgium
- Prior art keywords
- medicaments
- preparation
- acid derivatives
- lysergic acid
- novel
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- ZAGRKAFMISFKIO-QMTHXVAHSA-N lysergic acid Chemical class C1=CC(C2=C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-QMTHXVAHSA-N 0.000 title 1
- ARTRTLXKTHJPRW-ILZDJORESA-N (6ar,9s,10ar)-9-(diethylsulfamoylamino)-4-ethyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline Chemical compound C1=CC([C@H]2C[C@@H](CN(C)[C@@H]2C2)NS(=O)(=O)N(CC)CC)=C3C2=CN(CC)C3=C1 ARTRTLXKTHJPRW-ILZDJORESA-N 0.000 abstract 1
- VBDRBXHZZQMXPV-FBBABVLZSA-N C1=CC([C@H]2C[C@@H](CN(C)[C@@H]2C2)NS(=O)(=O)N(CC)CC)=C3C2=CN(C(C)C)C3=C1 Chemical compound C1=CC([C@H]2C[C@@H](CN(C)[C@@H]2C2)NS(=O)(=O)N(CC)CC)=C3C2=CN(C(C)C)C3=C1 VBDRBXHZZQMXPV-FBBABVLZSA-N 0.000 abstract 1
- 102000003946 Prolactin Human genes 0.000 abstract 1
- 108010057464 Prolactin Proteins 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 239000000939 antiparkinson agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229940097325 prolactin Drugs 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La présente invention a pour objet 1a N,N-diéthyl-N'- ((8 alpha)-1-éthyl-6-méthyl-ergoline-8-yl)-sulfamide et la N,N-diéthyl-N'-((8 alpha)-1-isopropyl-6-méthyl-ergoline-8-yl)-sulfamide (I). Ces composés peuvent etre utilisés comme médicaments, en particulier comme agents anti-parkinsoniens, comme inhibiteurs de la sécrétion de la prolactine, et comme agents anti-dépresseurs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH86383A CH652720A5 (en) | 1983-02-16 | 1983-02-16 | Ergoline derivatives, their preparation and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE898873A true BE898873A (fr) | 1984-08-10 |
Family
ID=4196935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE1/10956A BE898873A (fr) | 1983-02-16 | 1984-02-10 | Nouveaux derives de l'acide lysergique, leur preparation et leur utilisation comme medicaments |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE898873A (fr) |
| CH (1) | CH652720A5 (fr) |
| LU (1) | LU85212A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2521965A1 (fr) * | 2003-04-11 | 2004-10-28 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Analogues chimeres de la somatostatine-dopamine |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素－多巴胺嵌合體類似物 |
| CN104768565B (zh) | 2012-11-01 | 2017-04-26 | 益普生制药股份有限公司 | 促生长素抑制素类似物及其二聚体 |
-
1983
- 1983-02-16 CH CH86383A patent/CH652720A5/de not_active IP Right Cessation
-
1984
- 1984-02-10 BE BE1/10956A patent/BE898873A/fr unknown
- 1984-02-15 LU LU85212A patent/LU85212A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH652720A5 (en) | 1985-11-29 |
| LU85212A1 (fr) | 1984-11-08 |
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