BE903041A - PHENETHANOLAMINE DERIVATIVES AND THEIR PREPARATION PROCESS. - Google Patents
PHENETHANOLAMINE DERIVATIVES AND THEIR PREPARATION PROCESS.Info
- Publication number
- BE903041A BE903041A BE0/215451A BE215451A BE903041A BE 903041 A BE903041 A BE 903041A BE 0/215451 A BE0/215451 A BE 0/215451A BE 215451 A BE215451 A BE 215451A BE 903041 A BE903041 A BE 903041A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation process
- phenethanolamine derivatives
- derivatives
- phenethanol
- solvates
- Prior art date
Links
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical class NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Dérivés de la phénéthanol-amine de formule générale I, dans laquelle R est un atome d'hydrogène ou un radical alkyle en C1 à C3 à chaine droite et n egal à 1 ou 2, ainsi que leurs sels d'addition d'acides physiologiquement acceptables, leurs produits de solvatation et esters métaboliquement labiles et l'utilisation de ces composés dans le traitement de l'insuffisance cardiaque et d'autres affections analogues.Phenethanol-amine derivatives of general formula I, in which R is a hydrogen atom or a straight chain C1 to C3 alkyl radical and equal to 1 or 2, as well as their physiologically acid addition salts acceptable, their solvates and metabolically labile esters and the use of these compounds in the treatment of heart failure and other similar conditions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848420303A GB8420303D0 (en) | 1984-08-09 | 1984-08-09 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE903041A true BE903041A (en) | 1986-02-10 |
Family
ID=10565130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/215451A BE903041A (en) | 1984-08-09 | 1985-08-09 | PHENETHANOLAMINE DERIVATIVES AND THEIR PREPARATION PROCESS. |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS6183154A (en) |
| KR (1) | KR860001783A (en) |
| AU (1) | AU4590885A (en) |
| BE (1) | BE903041A (en) |
| CH (1) | CH667870A5 (en) |
| DE (1) | DE3528700A1 (en) |
| DK (1) | DK364185A (en) |
| ES (5) | ES8703829A1 (en) |
| FI (1) | FI853057A7 (en) |
| FR (1) | FR2568874B1 (en) |
| GB (2) | GB8420303D0 (en) |
| GR (1) | GR851949B (en) |
| HU (1) | HU196171B (en) |
| IL (1) | IL76062A (en) |
| IT (1) | IT1184685B (en) |
| LU (1) | LU86038A1 (en) |
| MY (1) | MY102187A (en) |
| NL (1) | NL8502212A (en) |
| NO (1) | NO853151L (en) |
| NZ (1) | NZ213055A (en) |
| PH (1) | PH21664A (en) |
| PT (1) | PT80936B (en) |
| SE (1) | SE8503763L (en) |
| ZA (1) | ZA856021B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1165845A (en) * | 1955-05-28 | 1958-10-29 | Philips Nv | Secondary amines bearing substituents and their preparation |
| ATE1899T1 (en) * | 1979-06-16 | 1982-12-15 | Beecham Group Plc | SECONDARY AMINES, THEIR PRODUCTION AND USE IN PHARMACEUTICAL COMPOSITIONS. |
-
1984
- 1984-08-09 GB GB848420303A patent/GB8420303D0/en active Pending
-
1985
- 1985-08-08 GR GR851949A patent/GR851949B/el unknown
- 1985-08-08 AU AU45908/85A patent/AU4590885A/en not_active Abandoned
- 1985-08-08 ES ES546010A patent/ES8703829A1/en not_active Expired
- 1985-08-09 IT IT48467/85A patent/IT1184685B/en active
- 1985-08-09 KR KR1019850005741A patent/KR860001783A/en not_active Withdrawn
- 1985-08-09 CH CH3433/85A patent/CH667870A5/en not_active IP Right Cessation
- 1985-08-09 GB GB08520111A patent/GB2162845B/en not_active Expired
- 1985-08-09 NZ NZ213055A patent/NZ213055A/en unknown
- 1985-08-09 JP JP60174406A patent/JPS6183154A/en active Pending
- 1985-08-09 BE BE0/215451A patent/BE903041A/en not_active IP Right Cessation
- 1985-08-09 FR FR8512245A patent/FR2568874B1/en not_active Expired
- 1985-08-09 IL IL76062A patent/IL76062A/en unknown
- 1985-08-09 SE SE8503763A patent/SE8503763L/en not_active Application Discontinuation
- 1985-08-09 FI FI853057A patent/FI853057A7/en not_active Application Discontinuation
- 1985-08-09 DE DE19853528700 patent/DE3528700A1/en not_active Withdrawn
- 1985-08-09 NO NO853151A patent/NO853151L/en unknown
- 1985-08-09 PH PH32623A patent/PH21664A/en unknown
- 1985-08-09 ZA ZA856021A patent/ZA856021B/en unknown
- 1985-08-09 LU LU86038A patent/LU86038A1/en unknown
- 1985-08-09 PT PT80936A patent/PT80936B/en unknown
- 1985-08-09 NL NL8502212A patent/NL8502212A/en not_active Application Discontinuation
- 1985-08-09 DK DK364185A patent/DK364185A/en not_active Application Discontinuation
- 1985-08-09 HU HU853082A patent/HU196171B/en unknown
-
1986
- 1986-02-17 ES ES552097A patent/ES8801783A1/en not_active Expired
-
1987
- 1987-02-16 ES ES557416A patent/ES8801784A1/en not_active Expired
- 1987-02-16 ES ES557414A patent/ES8802487A1/en not_active Expired
- 1987-02-16 ES ES557415A patent/ES8802488A1/en not_active Expired
- 1987-10-01 MY MYPI87002763A patent/MY102187A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: GLAXO GROUP LTD Effective date: 19900831 |