BE905332A - NOVEL ANTIBIOTIC AND ANTITUMOR SUBSTANCES, PROCESS FOR OBTAINING THE SAME AND INSULATION; PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Google Patents

NOVEL ANTIBIOTIC AND ANTITUMOR SUBSTANCES, PROCESS FOR OBTAINING THE SAME AND INSULATION; PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Info

Publication number
BE905332A
BE905332A BE0/217084A BE217084A BE905332A BE 905332 A BE905332 A BE 905332A BE 0/217084 A BE0/217084 A BE 0/217084A BE 217084 A BE217084 A BE 217084A BE 905332 A BE905332 A BE 905332A
Authority
BE
Belgium
Prior art keywords
pharmaceutical compositions
insulation
obtaining
same
compositions containing
Prior art date
Application number
BE0/217084A
Other languages
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE905332A publication Critical patent/BE905332A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

D'après le procédé les substances BBM-1675C et BBM-1675D ont été obtenues par hydrolyse chimique sélective des composants biologiquement actifs BBM-1675A1 (espéramicine A1) ou BBM-1675A2 (espéramicine A2). Le procédé permet notamment la réalisation de compositions pharmaceutiques antimicrobiennes et antitumorales.According to the process the substances BBM-1675C and BBM-1675D were obtained by selective chemical hydrolysis of the biologically active components BBM-1675A1 (Esperamicin A1) or BBM-1675A2 (Esperamicin A2). The method allows in particular the production of antimicrobial and antitumor pharmaceutical compositions.

BE0/217084A 1985-08-27 1986-08-26 NOVEL ANTIBIOTIC AND ANTITUMOR SUBSTANCES, PROCESS FOR OBTAINING THE SAME AND INSULATION; PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. BE905332A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27

Publications (1)

Publication Number Publication Date
BE905332A true BE905332A (en) 1987-02-26

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217084A BE905332A (en) 1985-08-27 1986-08-26 NOVEL ANTIBIOTIC AND ANTITUMOR SUBSTANCES, PROCESS FOR OBTAINING THE SAME AND INSULATION; PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Country Status (26)

Country Link
JP (2) JPH0733393B2 (en)
KR (1) KR920010226B1 (en)
AT (1) AT392971B (en)
AU (1) AU604464B2 (en)
BE (1) BE905332A (en)
CA (1) CA1307256C (en)
CH (1) CH668598A5 (en)
CY (1) CY1676A (en)
DE (1) DE3629052C2 (en)
DK (1) DK170671B1 (en)
ES (1) ES2002728A6 (en)
FI (1) FI83422C (en)
FR (1) FR2586686B1 (en)
GB (1) GB2179649A (en)
GR (1) GR862160B (en)
HK (1) HK793A (en)
HU (1) HU197915B (en)
IE (1) IE59204B1 (en)
IL (1) IL79519A0 (en)
IT (1) IT1229176B (en)
LU (1) LU86562A1 (en)
NL (1) NL8602165A (en)
PT (1) PT83261B (en)
SE (2) SE469632B (en)
SG (1) SG109692G (en)
ZA (1) ZA865796B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0276485B1 (en) * 1987-01-30 2002-06-12 American Cyanamid Company Dihydro derivatives of LL-E33288 antibiotics
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (en) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heating boiler for hot flue gases
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (en) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd Novel antibiotic substance sf-2288 and its preparation
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
GB8620118D0 (en) 1986-10-01
CY1676A (en) 1993-10-10
FI863405A0 (en) 1986-08-22
IT1229176B (en) 1991-07-23
HU197915B (en) 1989-06-28
IE59204B1 (en) 1994-01-26
NL8602165A (en) 1987-03-16
FR2586686B1 (en) 1990-02-02
LU86562A1 (en) 1987-03-06
FI863405L (en) 1987-02-28
KR920010226B1 (en) 1992-11-21
FI83422C (en) 1991-07-10
DE3629052A1 (en) 1987-05-07
IT8621527A0 (en) 1986-08-26
GR862160B (en) 1986-12-31
GB2179649A (en) 1987-03-11
CA1307256C (en) 1992-09-08
ZA865796B (en) 1987-04-29
FR2586686A1 (en) 1987-03-06
KR870002269A (en) 1987-03-30
PT83261B (en) 1989-05-12
AU604464B2 (en) 1990-12-20
JPH0733393B2 (en) 1995-04-12
SE8603597D0 (en) 1986-08-26
AT392971B (en) 1991-07-25
GB2179649B (en) 1989-10-25
SE9200428D0 (en) 1992-02-13
SE469632B (en) 1993-08-09
DK170671B1 (en) 1995-11-27
DE3629052C2 (en) 1995-09-28
FI83422B (en) 1991-03-28
IE862280L (en) 1987-02-27
ES2002728A6 (en) 1988-10-01
DK406086A (en) 1987-02-28
HK793A (en) 1993-01-15
IL79519A0 (en) 1986-10-31
HUT44035A (en) 1988-01-28
PT83261A (en) 1986-09-01
JPH07233186A (en) 1995-09-05
DK406086D0 (en) 1986-08-26
SE9200428L (en) 1993-08-14
JPS62116589A (en) 1987-05-28
ATA231786A (en) 1990-12-15
AU6175186A (en) 1987-03-05
SG109692G (en) 1992-12-24
SE8603597L (en) 1987-02-28
CH668598A5 (en) 1989-01-13

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BRISTOL-MYERS CY

Effective date: 19960831