BG100367A - The use of esters of n-alkylated, 1,4-dihydropyrimidinedicarboxylic acids as medicamentous forms - Google Patents

The use of esters of n-alkylated, 1,4-dihydropyrimidinedicarboxylic acids as medicamentous forms

Info

Publication number
BG100367A
BG100367A BG100367A BG10036796A BG100367A BG 100367 A BG100367 A BG 100367A BG 100367 A BG100367 A BG 100367A BG 10036796 A BG10036796 A BG 10036796A BG 100367 A BG100367 A BG 100367A
Authority
BG
Bulgaria
Prior art keywords
esters
alkylated
acids
dihydropyrimidinedicarboxylic
medicamentous forms
Prior art date
Application number
BG100367A
Other languages
Bulgarian (bg)
Inventor
Siegfried Zaiss
Dieter Neuser
Johannes-Peter Stasch
Siegfried Goldmann
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG100367A publication Critical patent/BG100367A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the use of esters of N-alkylated 1,4-dihydropyridinedicarboxylic acids having the general formula some of which are already known. In the formula radicals R1 to R6 have the meanings listed in the description. The esters are used as medicamentous forms for the treatment of atherosclerosis, in particular for the prophylaxy of restenosis after angioplasty and cardiac surgery.
BG100367A 1993-08-27 1996-02-19 The use of esters of n-alkylated, 1,4-dihydropyrimidinedicarboxylic acids as medicamentous forms BG100367A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4328884A DE4328884A1 (en) 1993-08-27 1993-08-27 Use of N-alkylated 1,4-dihydropyridinecarboxylic acid esters as medicaments
PCT/EP1994/002723 WO1995005823A1 (en) 1993-08-27 1994-08-16 Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments

Publications (1)

Publication Number Publication Date
BG100367A true BG100367A (en) 1996-07-31

Family

ID=6496196

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100367A BG100367A (en) 1993-08-27 1996-02-19 The use of esters of n-alkylated, 1,4-dihydropyrimidinedicarboxylic acids as medicamentous forms

Country Status (13)

Country Link
EP (1) EP0714301A1 (en)
JP (1) JPH09501923A (en)
KR (1) KR960703594A (en)
CN (1) CN1129906A (en)
AU (1) AU7613594A (en)
BG (1) BG100367A (en)
CA (1) CA2170285A1 (en)
CZ (1) CZ43896A3 (en)
DE (1) DE4328884A1 (en)
HU (1) HUT75302A (en)
NO (1) NO960777L (en)
PL (1) PL313116A1 (en)
WO (1) WO1995005823A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19741694C2 (en) * 1997-09-18 2002-10-31 Schering Ag Use of complexes whose ligand is a bis-amine oxime derivative or an N¶2¶S¶2¶ derivative and whose central atom is a radionuclide
CA2470813A1 (en) 2001-12-20 2003-07-03 Bayer Healthcare Ag 1,4-dihydro-1,4-diphenylpyridine derivatives
EP2782573B1 (en) * 2011-11-24 2019-10-09 Richter Gedeon Nyrt. 1,4-dihydropyridine derivatives with hsp modulating activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
EP0169009A3 (en) * 1984-07-17 1988-08-31 FISONS plc Novel dihydropyridine derivatives and their production, formulation and use as pharmaceuticals
DE4011695A1 (en) * 1990-04-11 1991-10-17 Bayer Ag USE OF N-ALKYLATED 1,4-DIHYDROPYRIDE INDICARBOXIC ACID ESTERS AS DRUGS, NEW COMPOUNDS AND METHOD FOR THEIR PREPARATION

Also Published As

Publication number Publication date
CA2170285A1 (en) 1995-03-02
WO1995005823A1 (en) 1995-03-02
NO960777D0 (en) 1996-02-26
DE4328884A1 (en) 1995-03-02
HU9600472D0 (en) 1996-04-29
JPH09501923A (en) 1997-02-25
CZ43896A3 (en) 1996-05-15
EP0714301A1 (en) 1996-06-05
HUT75302A (en) 1997-05-28
CN1129906A (en) 1996-08-28
KR960703594A (en) 1996-08-31
AU7613594A (en) 1995-03-21
PL313116A1 (en) 1996-06-10
NO960777L (en) 1996-04-10

Similar Documents

Publication Publication Date Title
ES2114616T5 (en) INSULATED ALIFATIC DICARBOXILIC ACIDS.
UA48946C2 (en) Arylalkyldiazinones, method for their preparation, pharmaceutical composition, method of its preparation and treatment method
EP0335901A4 (en) Methods and compositions for the treatment of non-ige-mediated diseases
EP0625507A3 (en) Urea derivatives and their use as acat inhibitors
ATE237303T1 (en) USE OF COMPOSITIONS CONTAINING BENZOYL PEROXIDE, GLYCOLIC ACID AND ZINC FOR THE TREATMENT OF DERMATOLOGICAL DISEASES
MX9709915A (en) Peptidyl heterocycles useful in the treatment of thrombin related disorders.
DE69826695D1 (en) ARYL URINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY OR IMMUNOMODULATORY DISEASES
DE69434313D1 (en) SUPEROXIDE DISTUTASE MEMETICS
DE69532804D1 (en) USE OF MAILLARD REACTION INHIBITORS FOR TREATING DISEASES AFTER AMYLOIDOSIS
ZA943744B (en) Therapeutic substituted guanidines
MY115211A (en) Novel amino acid derivatives, their preparation and use
NZ332096A (en) Alpha-hydroxylic acid derivatives their production and use in treating conditions requiring endothelin inhibition
DE69405919D1 (en) Compositions for the treatment of keratin fibers
MX9701187A (en) Novel n-substituted naphthofused lactams.
MY109060A (en) New derivatives of b-amino acids
PL346143A1 (en) Tan-1057 derivatives
MY132057A (en) Quinoxalinones, a process for their preparation and their use
EA200000242A1 (en) FANHINONA APPLICATION FOR THE TREATMENT OF ALZHEIMER'S DISEASE
WO1995015161A3 (en) Medicament for treating heart insufficiency
DE69818823D1 (en) DIPOHOSPHONIC ACID SALTS FOR THE TREATMENT OF OSTEOPOROSIS
NO991734L (en) Pyrazolinones for the treatment of potency disorders
PL310655A1 (en) Derivatives of hydroxymethylfurasane carboxylic acid and their application in treating cardiovascular diseases
LV11593A (en) The use of dimethicone in the treatment of constipation
GR3022471T3 (en) Novel cardioprotective agents.
BR9710992A (en) Anticovulsive derivatives useful in the treatment of psoriasis