BG103252A - Използване на бензопираноли за лечение на неврологични смущения - Google Patents

Използване на бензопираноли за лечение на неврологични смущения

Info

Publication number
BG103252A
BG103252A BG103252A BG10325299A BG103252A BG 103252 A BG103252 A BG 103252A BG 103252 A BG103252 A BG 103252A BG 10325299 A BG10325299 A BG 10325299A BG 103252 A BG103252 A BG 103252A
Authority
BG
Bulgaria
Prior art keywords
treatment
pains
benzopyranols
neurological disorders
neuralgia
Prior art date
Application number
BG103252A
Other languages
English (en)
Inventor
Andrew Parsons
Mervyn Thompson
Neil Upton
Johan EVANS
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of BG103252A publication Critical patent/BG103252A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Изобретението се отнася до бензопиранови производни и техни аналози, които се прилагат за лечение и/или профилактика на дегенеративни болести като хорея на Huntington, шизофрения, неврологичен дефицит, свързан със СПИН, смущения в съня (включително смущения в циркадния ритъм, безсъние и нарколепсия), тикове, по-специално синдром на Gilles de la Tourette, мозъчни травми, шум в ушите, невралгия, особено тригеминусова невралгия, невропатични болки,зъбобол, болки при ракови заболявания, моторно-неврологични смущения, атаксия, мускулна ригидност (спазматичност) и временна дисфункция на мандибуларната става.
BG103252A 1996-09-18 1999-03-15 Използване на бензопираноли за лечение на неврологични смущения BG103252A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9619492.3A GB9619492D0 (en) 1996-09-18 1996-09-18 Novel treatment
PCT/EP1997/005168 WO1998011890A1 (en) 1996-09-18 1997-09-15 Use of benzopyranols to treat neurological disorders

Publications (1)

Publication Number Publication Date
BG103252A true BG103252A (bg) 1999-09-30

Family

ID=10800127

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103252A BG103252A (bg) 1996-09-18 1999-03-15 Използване на бензопираноли за лечение на неврологични смущения

Country Status (30)

Country Link
EP (1) EP0939630B1 (bg)
JP (1) JP2001500520A (bg)
KR (1) KR20000036184A (bg)
CN (1) CN1230885A (bg)
AP (1) AP9901473A0 (bg)
AR (1) AR008838A1 (bg)
AT (1) ATE270102T1 (bg)
AU (1) AU730465B2 (bg)
BG (1) BG103252A (bg)
BR (1) BR9712030A (bg)
CA (1) CA2266681A1 (bg)
DE (1) DE69729735T2 (bg)
DZ (1) DZ2311A1 (bg)
EA (1) EA199900306A1 (bg)
ES (1) ES2223075T3 (bg)
GB (1) GB9619492D0 (bg)
HU (1) HUP9904638A3 (bg)
ID (2) ID23175A (bg)
IL (1) IL128786A0 (bg)
MA (1) MA24321A1 (bg)
NO (1) NO991292L (bg)
NZ (1) NZ334271A (bg)
OA (1) OA10998A (bg)
PE (1) PE109898A1 (bg)
PL (1) PL332313A1 (bg)
SK (1) SK35199A3 (bg)
TR (1) TR199900527T2 (bg)
UY (1) UY24717A1 (bg)
WO (1) WO1998011890A1 (bg)
ZA (1) ZA978359B (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US20110319482A1 (en) * 2008-06-05 2011-12-29 Peter Blower Novel treatments
US20130281524A1 (en) * 2008-06-05 2013-10-24 Peter Blower Novel treatments
PT2464645T (pt) 2009-07-27 2017-10-11 Gilead Sciences Inc Compostos heterocíclicos fusionados como moduladores do canal de iões
AU2010325755A1 (en) * 2009-12-03 2012-06-21 Proximagen Ltd Treatment of infectious diseases
WO2011067608A1 (en) * 2009-12-03 2011-06-09 Minster Research Ltd Treatment of allodynia and hyperalgesia
WO2012003392A1 (en) 2010-07-02 2012-01-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
AU2012253653A1 (en) 2011-05-10 2013-05-02 Gilead Sciences, Inc. Fused heterocyclic compounds as sodium channel modulators
NO3175985T3 (bg) 2011-07-01 2018-04-28
TWI622583B (zh) 2011-07-01 2018-05-01 基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
CN106397317B (zh) * 2016-09-26 2019-03-22 天津师范大学 1,2,3,4-四氢喹啉化合物及其合成方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9112721D0 (en) * 1991-06-13 1991-07-31 Smithkline Beecham Plc Novel treatment
US5510375A (en) * 1993-11-19 1996-04-23 Warner-Lambert Company Coumarin derivatives as protease inhibitors and antiviral agents
GB9411635D0 (en) * 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
ATE250052T1 (de) * 1994-06-10 2003-10-15 Smithkline Beecham Plc Benzopyrane und deren verwendung als heilmittel

Also Published As

Publication number Publication date
SK35199A3 (en) 2000-07-11
TR199900527T2 (xx) 1999-06-21
WO1998011890A1 (en) 1998-03-26
ZA978359B (en) 1999-03-17
CN1230885A (zh) 1999-10-06
NZ334271A (en) 2001-03-30
EP0939630A1 (en) 1999-09-08
CA2266681A1 (en) 1998-03-26
HUP9904638A3 (en) 2001-08-28
ES2223075T3 (es) 2005-02-16
AU4704797A (en) 1998-04-14
UY24717A1 (es) 2001-08-27
IL128786A0 (en) 2000-01-31
EP0939630B1 (en) 2004-06-30
AR008838A1 (es) 2000-02-23
NO991292D0 (no) 1999-03-17
DZ2311A1 (fr) 2002-12-28
NO991292L (no) 1999-03-17
HUP9904638A2 (hu) 2001-05-28
KR20000036184A (ko) 2000-06-26
PL332313A1 (en) 1999-08-30
EA199900306A1 (ru) 1999-08-26
MA24321A1 (fr) 1998-04-01
DE69729735T2 (de) 2005-07-14
AP9901473A0 (en) 1999-03-31
JP2001500520A (ja) 2001-01-16
ATE270102T1 (de) 2004-07-15
AU730465B2 (en) 2001-03-08
PE109898A1 (es) 1999-03-21
OA10998A (en) 2003-03-04
ID19542A (id) 1998-07-23
DE69729735D1 (de) 2004-08-05
BR9712030A (pt) 1999-08-24
GB9619492D0 (en) 1996-10-30
ID23175A (id) 2000-03-23

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