BG103820A - Приложение на амиди на фенилциклохексилкарбоксилната киселина като лекарствени средства - Google Patents

Приложение на амиди на фенилциклохексилкарбоксилната киселина като лекарствени средства Download PDF

Info

Publication number: BG103820A
Authority: BG; Bulgaria
Prior art keywords: acid; carbon atoms; formula; general formula; acid amides
Prior art date: 1995-02-01

Application number

BG103820/99A

Other languages

Bulgarian (bg)

English (en)

Inventor

Matthias Mueller-Gliemann

Ulrich Mueller

Martin Beuck

Siegfried Zaiss

Christoph Gerdes

Anke Domdey-Bette

Rudi Gruetzmann

Stefan Lohmer

Stefan Wohlfeil

Uezkan YALKINOGLU

James Elting

Dirk Denzer

Original Assignee

Bayer Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-01

Filing date

1996-01-30

Publication date

2001-09-28

1996-01-30 Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft

2001-09-28 Publication of BG103820A publication Critical patent/BG103820A/bg

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Hematology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG103820/99A 1995-02-01 1996-01-30 Приложение на амиди на фенилциклохексилкарбоксилната киселина като лекарствени средства BG103820A (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19503160A DE19503160A1 (de)	1995-02-01	1995-02-01	Verwendung von Phenylcyclohexylcarbonsäureamiden

Publications (1)

Publication Number	Publication Date
BG103820A true BG103820A (bg)	2001-09-28

Family

ID=7752849

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BG103820/99A BG103820A (bg)	1995-02-01	1996-01-30	Приложение на амиди на фенилциклохексилкарбоксилната киселина като лекарствени средства
BG100326A BG63044B1 (bg)	1995-02-01	1996-01-30	Амиди на фенилциклохексилкарбоксилната киселина, метод за получаването им и тяхната употреба като лекарствени средства

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BG100326A BG63044B1 (bg)	1995-02-01	1996-01-30	Амиди на фенилциклохексилкарбоксилната киселина, метод за получаването им и тяхната употреба като лекарствени средства

Country Status (31)

Country	Link
US (1)	US5935983A (cs)
EP (1)	EP0725064A1 (cs)
JP (1)	JPH08253453A (cs)
KR (1)	KR960031442A (cs)
CN (1)	CN1137380A (cs)
AR (1)	AR002272A1 (cs)
AU (1)	AU710235B2 (cs)
BG (2)	BG103820A (cs)
CA (1)	CA2168317A1 (cs)
CZ (1)	CZ29196A3 (cs)
DE (1)	DE19503160A1 (cs)
DZ (1)	DZ1986A1 (cs)
EE (1)	EE9600023A (cs)
FI (1)	FI960425L (cs)
HR (1)	HRP960017A2 (cs)
HU (1)	HUP9600227A3 (cs)
IL (1)	IL116931A (cs)
MA (1)	MA23794A1 (cs)
NO (1)	NO309841B1 (cs)
NZ (1)	NZ280905A (cs)
PL (1)	PL312546A1 (cs)
RO (1)	RO117256B1 (cs)
RU (1)	RU2158261C2 (cs)
SG (1)	SG42329A1 (cs)
SK (1)	SK13796A3 (cs)
SV (1)	SV1996000008A (cs)
TN (1)	TNSN96016A1 (cs)
TW (1)	TW448176B (cs)
UA (1)	UA35623C2 (cs)
YU (1)	YU5896A (cs)
ZA (1)	ZA96725B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6911462B2 (en) *	1998-05-22	2005-06-28	Avanir Pharmaceuticals	Benzimidazole compounds for regulating IgE
DE19924818A1 (de)	1999-05-29	2000-11-30	Bayer Ag	Substituierte Phenylcyclohexancarbonsäureamide
DE19924819A1 (de) *	1999-05-29	2000-11-30	Bayer Ag	Substituierte Phenylcyclohexancarbonsäurebenzylamid (Adenosinaufnahmeinhibitoren)
CZ20032691A3 (en) *	2001-03-12	2004-04-14	Avanir Pharmaceuticals	Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
DE10150310A1 (de) *	2001-10-11	2003-04-24	Bayer Ag	Substituierte Piperazincyclohexancarbonsäureamide und ihre Verwendung
US6934951B2 (en)	2002-01-17	2005-08-23	Intel Corporation	Parallel processor with functional pipeline providing programming engines by supporting multiple contexts and critical section
TW200304820A (en) *	2002-03-25	2003-10-16	Avanir Pharmaceuticals	Use of benzimidazole analogs in the treatment of cell proliferation
TW200400040A (en) *	2002-05-17	2004-01-01	Wyeth Corp	Hormone replacement therapy
WO2004024655A2 (en)	2002-09-12	2004-03-25	Avanir Pharmaceuticals	Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) *	2002-09-12	2007-03-21	Avanir Pharmaceuticals	Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
FR2852957B1 (fr) *	2003-03-31	2005-06-10	Sod Conseils Rech Applic	Nouveaux derives d'imidazo-pyridine et leur utilisation en tant que medicament
JO2355B1 (en) *	2003-04-15	2006-12-12	ميرك شارب اند دوم كوربوريشن	Hereditary calcitonin polypeptide receptor antagonists
EP1651198A2 (en) *	2003-08-08	2006-05-03	Avanir Pharmaceuticals	Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4224133A1 (de) *	1992-07-22	1994-01-27	Thomae Gmbh Dr K	Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4226109A1 (de) *	1992-08-07	1994-02-10	Bayer Ag	Verwendung von ASS zur Hemmung von Plaquebildung
DE4304455A1 (de) *	1993-02-15	1994-08-18	Bayer Ag	Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate
US5358959A (en) *	1993-02-18	1994-10-25	President And Fellows Of Harvard University	Methods for treating arteriosclerosis
DE4401893A1 (de) *	1994-01-24	1995-07-27	Bayer Ag	Substituierte Arylharnstoffe

1995
- 1995-02-01 DE DE19503160A patent/DE19503160A1/de not_active Withdrawn
1996
- 1996-01-15 HR HR19503160.1A patent/HRP960017A2/hr not_active Application Discontinuation
- 1996-01-19 EP EP96100760A patent/EP0725064A1/de not_active Withdrawn
- 1996-01-22 TW TW085100684A patent/TW448176B/zh active
- 1996-01-22 AR ARP960101106A patent/AR002272A1/es not_active Application Discontinuation
- 1996-01-26 RO RO96-00152A patent/RO117256B1/ro unknown
- 1996-01-29 CA CA002168317A patent/CA2168317A1/en not_active Abandoned
- 1996-01-29 JP JP8033174A patent/JPH08253453A/ja active Pending
- 1996-01-29 IL IL11693196A patent/IL116931A/xx not_active IP Right Cessation
- 1996-01-29 NZ NZ280905A patent/NZ280905A/en unknown
- 1996-01-30 FI FI960425A patent/FI960425L/fi unknown
- 1996-01-30 BG BG103820/99A patent/BG103820A/bg unknown
- 1996-01-30 BG BG100326A patent/BG63044B1/bg unknown
- 1996-01-30 YU YU5896A patent/YU5896A/sh unknown
- 1996-01-30 AU AU42240/96A patent/AU710235B2/en not_active Ceased
- 1996-01-30 PL PL96312546A patent/PL312546A1/xx unknown
- 1996-01-30 UA UA96010375A patent/UA35623C2/uk unknown
- 1996-01-31 CZ CZ96291A patent/CZ29196A3/cs unknown
- 1996-01-31 NO NO960414A patent/NO309841B1/no not_active IP Right Cessation
- 1996-01-31 DZ DZ960027A patent/DZ1986A1/fr active
- 1996-01-31 KR KR1019960002344A patent/KR960031442A/ko not_active Ceased
- 1996-01-31 SK SK137-96A patent/SK13796A3/sk unknown
- 1996-01-31 EE EE9600023A patent/EE9600023A/xx unknown
- 1996-01-31 ZA ZA96725A patent/ZA96725B/xx unknown
- 1996-01-31 RU RU96101800/04A patent/RU2158261C2/ru active
- 1996-02-01 HU HU9600227A patent/HUP9600227A3/hu unknown
- 1996-02-01 CN CN96102574A patent/CN1137380A/zh active Pending
- 1996-02-01 TN TNTNSN96016A patent/TNSN96016A1/fr unknown
- 1996-02-01 SV SV1996000008A patent/SV1996000008A/es unknown
- 1996-02-01 MA MA24149A patent/MA23794A1/fr unknown
- 1996-02-01 SG SG1996000776A patent/SG42329A1/en unknown
1997
- 1997-10-24 US US08/960,075 patent/US5935983A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EE9600023A (et)	1996-08-15
AR002272A1 (es)	1998-03-11
DZ1986A1 (fr)	2002-10-15
YU5896A (sh)	1998-12-23
AU710235B2 (en)	1999-09-16
MA23794A1 (fr)	1996-10-01
NO309841B1 (no)	2001-04-09
EP0725064A1 (de)	1996-08-07
TNSN96016A1 (fr)	2005-03-15
SK13796A3 (en)	1996-10-02
HRP960017A2 (en)	1997-12-31
TW448176B (en)	2001-08-01
PL312546A1 (en)	1996-08-05
RO117256B1 (ro)	2001-12-28
FI960425A7 (fi)	1996-08-02
FI960425A0 (fi)	1996-01-30
BG63044B1 (bg)	2001-02-28
NO960414D0 (no)	1996-01-31
CZ29196A3 (en)	1996-08-14
US5935983A (en)	1999-08-10
JPH08253453A (ja)	1996-10-01
ZA96725B (en)	1996-08-20
NZ280905A (en)	1996-12-20
HUP9600227A2 (en)	1996-12-30
FI960425L (fi)	1996-08-02
SG42329A1 (en)	1997-08-15
HU9600227D0 (en)	1996-03-28
NO960414L (no)	1996-08-02
CN1137380A (zh)	1996-12-11
DE19503160A1 (de)	1996-08-08
IL116931A (en)	2000-06-01
HUP9600227A3 (en)	2000-03-28
RU2158261C2 (ru)	2000-10-27
SV1996000008A (es)	1996-11-04
IL116931A0 (en)	1996-05-14
UA35623C2 (uk)	2001-04-16
BG100326A (bg)	1996-08-30
CA2168317A1 (en)	1996-08-02
KR960031442A (ko)	1996-09-17
AU4224096A (en)	1996-08-08

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