BG104692A - Extended release tiagabine formulation - Google Patents

Extended release tiagabine formulation

Info

Publication number: BG104692A
Authority: BG; Bulgaria
Prior art keywords: extended release; formulation; release tiagabine; tiagabine; administered
Prior art date: 1998-01-22

Application number

BG104692A

Other languages

Bulgarian (bg)

English (en)

Inventor

Francisco Alvarez

Russell SLADE

Kathleen APFELBAUM

David Brown

Linda Gustavson

Original Assignee

Abbott Laboratories

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-22

Filing date

2000-08-15

Publication date

2001-05-31

2000-08-15 Application filed by Abbott Laboratories filed Critical Abbott Laboratories

2001-05-31 Publication of BG104692A publication Critical patent/BG104692A/xx

Links

238000013265 extended release Methods 0.000 title abstract 2
238000009472 formulation Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
PBJUNZJWGZTSKL-MRXNPFEDSA-N tiagabine Chemical compound C1=CSC(C(=CCCN2C[C@@H](CCC2)C(O)=O)C2=C(C=CS2)C)=C1C PBJUNZJWGZTSKL-MRXNPFEDSA-N 0.000 title abstract 2
229960001918 tiagabine Drugs 0.000 title abstract 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BG104692A 1998-01-22 2000-08-15 Extended release tiagabine formulation BG104692A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7213098P	1998-01-22	1998-01-22
PCT/US1999/001242 WO1999037302A1 (en)	1998-01-22	1999-01-22	Extended release tiagabine formulations with reduced side-effects

Publications (1)

Publication Number	Publication Date
BG104692A true BG104692A (en)	2001-05-31

Family

ID=22105780

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG104692A BG104692A (en)	1998-01-22	2000-08-15	Extended release tiagabine formulation

Country Status (23)

Country	Link
US (1)	US20070053980A1 (de)
EP (1)	EP1049470B1 (de)
JP (1)	JP2002501022A (de)
KR (1)	KR20010034313A (de)
CN (1)	CN1145484C (de)
AR (1)	AR018041A1 (de)
AT (1)	ATE350035T1 (de)
AU (1)	AU2239599A (de)
BG (1)	BG104692A (de)
CA (1)	CA2318448A1 (de)
CO (1)	CO4970814A1 (de)
DE (1)	DE69934670D1 (de)
HU (1)	HUP0101739A3 (de)
IL (1)	IL137324A0 (de)
NO (1)	NO20003677L (de)
NZ (1)	NZ505725A (de)
PL (1)	PL194595B1 (de)
SA (1)	SA99200204B1 (de)
SK (1)	SK11072000A3 (de)
TR (2)	TR200505223T2 (de)
TW (1)	TW585787B (de)
WO (1)	WO1999037302A1 (de)
ZA (1)	ZA99407B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6872734B2 (en)	2000-10-20	2005-03-29	Abbott Laboratories	Use of tiagabine for treatment of diabetic neuropathy and migraine
KR100510270B1 (ko) *	2002-11-29	2005-08-26	센츄론(주)	펠렛타이저를 이용한 서방성 제제의 제조방법
CN102908327B (zh) *	2011-08-05	2015-03-11	江苏恒瑞医药股份有限公司	伊伐布雷定或其可药用盐的缓释制剂
KR102051132B1 (ko) *	2017-03-17	2019-12-02	주식회사 종근당	미라베그론 또는 이의 염을 포함하는 방출조절용 약제학적 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5009897A (en) *	1988-06-24	1991-04-23	Abbott Laboratories	Pharmaceutical granules and tablets made therefrom
US5126145A (en) *	1989-04-13	1992-06-30	Upsher Smith Laboratories Inc	Controlled release tablet containing water soluble medicament
US5273758A (en) *	1991-03-18	1993-12-28	Sandoz Ltd.	Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms
WO1995005808A1 (en) *	1993-08-24	1995-03-02	Abbott Laboratories	Oil-based tableting method
US5430021A (en) *	1994-03-18	1995-07-04	Pharmavene, Inc.	Hydrophobic drug delivery systems
ZA953078B (en) *	1994-04-28	1996-01-05	Alza Corp	Effective therapy for epilepsies
MX9708394A (es) *	1995-05-05	1998-02-28	Novo Nordisk As	Composicion farmaceutica que contiene clorhidrato de tiagabina y el proceso para su preparacion.
US5783212A (en) *	1996-02-02	1998-07-21	Temple University--of the Commonwealth System of Higher Education	Controlled release drug delivery system
AU8643698A (en) *	1997-08-01	1999-02-22	Elan Corporation, Plc	Controlled release pharmaceutical compositions containing tiagabine
US5843477A (en) *	1997-09-30	1998-12-01	Bayer Corporation	Lubricants for use in tabletting

1999
- 1999-01-20 ZA ZA9900407A patent/ZA99407B/xx unknown
- 1999-01-21 CO CO99003109A patent/CO4970814A1/es unknown
- 1999-01-22 IL IL13732499A patent/IL137324A0/xx unknown
- 1999-01-22 WO PCT/US1999/001242 patent/WO1999037302A1/en not_active Ceased
- 1999-01-22 CN CNB998040886A patent/CN1145484C/zh not_active Expired - Fee Related
- 1999-01-22 DE DE69934670T patent/DE69934670D1/de not_active Expired - Lifetime
- 1999-01-22 KR KR1020007008031A patent/KR20010034313A/ko not_active Ceased
- 1999-01-22 EP EP99902409A patent/EP1049470B1/de not_active Expired - Lifetime
- 1999-01-22 AU AU22395/99A patent/AU2239599A/en not_active Abandoned
- 1999-01-22 CA CA002318448A patent/CA2318448A1/en not_active Abandoned
- 1999-01-22 HU HU0101739A patent/HUP0101739A3/hu unknown
- 1999-01-22 SK SK1107-2000A patent/SK11072000A3/sk unknown
- 1999-01-22 NZ NZ505725A patent/NZ505725A/xx unknown
- 1999-01-22 JP JP2000528284A patent/JP2002501022A/ja not_active Withdrawn
- 1999-01-22 AR ARP990100254A patent/AR018041A1/es unknown
- 1999-01-22 TR TR2005/05223T patent/TR200505223T2/xx unknown
- 1999-01-22 TR TR2000/02102T patent/TR200002102T2/xx unknown
- 1999-01-22 AT AT99902409T patent/ATE350035T1/de not_active IP Right Cessation
- 1999-01-22 PL PL99342767A patent/PL194595B1/pl unknown
- 1999-03-16 TW TW088100990A patent/TW585787B/zh not_active IP Right Cessation
- 1999-06-01 SA SA99200204A patent/SA99200204B1/ar unknown
2000
- 2000-07-18 NO NO20003677A patent/NO20003677L/no not_active Application Discontinuation
- 2000-08-15 BG BG104692A patent/BG104692A/xx unknown
2006
- 2006-11-03 US US11/592,694 patent/US20070053980A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR20010034313A (ko)	2001-04-25
ATE350035T1 (de)	2007-01-15
EP1049470B1 (de)	2007-01-03
NZ505725A (en)	2003-01-31
DE69934670D1 (de)	2007-02-15
TW585787B (en)	2004-05-01
NO20003677L (no)	2000-09-20
JP2002501022A (ja)	2002-01-15
NO20003677D0 (no)	2000-07-18
TR200002102T2 (tr)	2000-12-21
HUP0101739A2 (hu)	2002-03-28
SA99200204B1 (ar)	2006-10-11
WO1999037302A1 (en)	1999-07-29
CA2318448A1 (en)	1999-07-29
ZA99407B (en)	1999-07-20
SK11072000A3 (sk)	2001-01-18
EP1049470A1 (de)	2000-11-08
AU2239599A (en)	1999-08-09
US20070053980A1 (en)	2007-03-08
PL342767A1 (en)	2001-07-02
PL194595B1 (pl)	2007-06-29
IL137324A0 (en)	2001-07-24
HUP0101739A3 (en)	2002-10-28
CO4970814A1 (es)	2000-11-07
CN1145484C (zh)	2004-04-14
TR200505223T2 (tr)	2006-04-21
AR018041A1 (es)	2001-10-31
CN1293571A (zh)	2001-05-02

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AU2277101A (en)	2001-07-03	Stable extended release oral dosage composition
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