BG105175A - Методи и трансдермални състави за облекчаване на болка - Google Patents
Методи и трансдермални състави за облекчаване на болка Download PDFInfo
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- BG105175A BG105175A BG105175A BG10517501A BG105175A BG 105175 A BG105175 A BG 105175A BG 105175 A BG105175 A BG 105175A BG 10517501 A BG10517501 A BG 10517501A BG 105175 A BG105175 A BG 105175A
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- compound
- amine
- composition
- patient
- pain
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- 229910001415 sodium ion Inorganic materials 0.000 description 1
- AEQFSUDEHCCHBT-UHFFFAOYSA-M sodium valproate Chemical compound [Na+].CCCC(C([O-])=O)CCC AEQFSUDEHCCHBT-UHFFFAOYSA-M 0.000 description 1
- KSRLIXGNPXAZHD-HAZZGOGXSA-M sodium;3-[(e)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-5-oxo-4h-imidazol-2-olate Chemical compound [Na+].[O-]C1=NC(=O)CN1\N=C\C1=CC=C(C=2C=CC(=CC=2)[N+]([O-])=O)O1 KSRLIXGNPXAZHD-HAZZGOGXSA-M 0.000 description 1
- 230000001148 spastic effect Effects 0.000 description 1
- 208000020431 spinal cord injury Diseases 0.000 description 1
- 210000003594 spinal ganglia Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 201000009032 substance abuse Diseases 0.000 description 1
- 231100000736 substance abuse Toxicity 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 150000003445 sucroses Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 208000012271 tenesmus Diseases 0.000 description 1
- 229960000351 terfenadine Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
- 229940102566 valproate Drugs 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- QYRYFNHXARDNFZ-UHFFFAOYSA-N venlafaxine hydrochloride Chemical compound [H+].[Cl-].C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 QYRYFNHXARDNFZ-UHFFFAOYSA-N 0.000 description 1
- 229960002416 venlafaxine hydrochloride Drugs 0.000 description 1
- 229940094720 viagra Drugs 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 229940039925 zyprexa Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/106,684 US6290986B1 (en) | 1996-10-24 | 1998-06-29 | Method and composition for transdermal administration of pharmacologic agents |
| US12290399P | 1999-03-05 | 1999-03-05 | |
| PCT/US1999/014653 WO2000000120A1 (fr) | 1998-06-29 | 1999-06-29 | Compositions antalgiques transdermiques et leurs methodes d'administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105175A true BG105175A (bg) | 2001-11-30 |
Family
ID=26803907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105175A BG105175A (bg) | 1998-06-29 | 2001-01-24 | Методи и трансдермални състави за облекчаване на болка |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1093348A4 (fr) |
| JP (1) | JP2002519310A (fr) |
| KR (1) | KR20010078754A (fr) |
| CN (1) | CN1331576A (fr) |
| AU (1) | AU4841599A (fr) |
| BG (1) | BG105175A (fr) |
| BR (1) | BR9912508A (fr) |
| CA (1) | CA2335837A1 (fr) |
| HR (1) | HRP20000905A2 (fr) |
| HU (1) | HUP0102728A3 (fr) |
| ID (1) | ID28213A (fr) |
| IL (1) | IL140420A0 (fr) |
| MX (1) | MXPA00012767A (fr) |
| NO (1) | NO20006604L (fr) |
| PL (1) | PL345216A1 (fr) |
| SK (1) | SK20012000A3 (fr) |
| TR (1) | TR200003801T2 (fr) |
| WO (1) | WO2000000120A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6572880B2 (en) * | 1996-10-24 | 2003-06-03 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| NZ500590A (en) | 1997-04-22 | 2001-11-30 | Cocensys Inc | Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof |
| EP1632235A3 (fr) * | 1999-07-01 | 2006-06-14 | Pharmacia & Upjohn Company LLC | utilisation d' inhibiteurs de recaptage de noradrenaline hautement selectifs pour traiter les maladies mentales |
| DE60022692T2 (de) | 1999-07-01 | 2006-06-22 | Pharmacia & Upjohn Co. Llc, Kalamazoo | (S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen |
| CA2325106A1 (fr) * | 1999-12-06 | 2001-06-06 | Stanley L. Gore | Compositions et methodes permettant de liberer des agents actifs dans le cerveau |
| IN191512B (fr) * | 2000-01-21 | 2003-12-06 | Panacea Biotech | |
| DE10032132A1 (de) * | 2000-07-01 | 2002-01-17 | Lohmann Therapie Syst Lts | Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung |
| EP1303265B1 (fr) * | 2000-07-20 | 2007-07-11 | Lauras AS | Utilisation d'inhibiteurs de cox-2 en tant qu'immunostimulants dans le traitement du vih ou du sida |
| DE10042412B4 (de) * | 2000-08-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Abgabe von Venlafaxin, und seine Verwendung |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| ATE482695T1 (de) | 2002-12-13 | 2010-10-15 | Durect Corp | Orale darreichungsform mit flüssigen hochviskosen trägersystemen |
| JP2005154368A (ja) * | 2003-11-27 | 2005-06-16 | Teikoku Seiyaku Co Ltd | ジソピラミド含有神経因性疼痛の鎮痛剤 |
| JP4807721B2 (ja) * | 2004-01-29 | 2011-11-02 | 株式会社 メドレックス | 消炎鎮痛外用剤 |
| AU2005287175B2 (en) | 2004-09-17 | 2011-12-01 | Durect Corporation | Sustained local anesthetic composition containing preferably a sugar ester such as SAIB |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| JP2007308403A (ja) * | 2006-05-17 | 2007-11-29 | Kenji Yoshida | 皮膚外用剤 |
| KR100880748B1 (ko) * | 2006-08-29 | 2009-02-02 | 정헌택 | 디메톡시커큐민을 함유하는 혈관재협착 방지용 조성물 |
| US8337883B2 (en) | 2006-11-03 | 2012-12-25 | Durect Corporation | Transdermal delivery systems |
| US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
| EP2219622A1 (fr) | 2007-12-06 | 2010-08-25 | Durect Corporation | Procédés utiles dans le traitement de la douleur, d'états rhumatismaux ou d'inflammations associées à un état chronique |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| KR101237927B1 (ko) * | 2009-05-07 | 2013-03-04 | (주)문엔제이 | 신경손상 및 신경질환 예방 또는 치료용 약학조성물 |
| US8491927B2 (en) | 2009-12-02 | 2013-07-23 | Nimble Epitech, Llc | Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor |
| TW201521769A (zh) | 2013-03-15 | 2015-06-16 | Durect Corp | 具有流變改質劑以減少溶解變異性之組成物 |
| AU2015217309A1 (en) * | 2014-02-11 | 2016-08-25 | Dr. Reddy's Laboratories Ltd. | Parenteral compositions of celecoxib |
| SG11201811760VA (en) | 2016-07-06 | 2019-01-30 | Durect Corp | Oral dosage form with drug composition, barrier layer and drug layer |
| AU2019365255B2 (en) | 2018-10-26 | 2025-06-12 | Viramal Limited | Mucoadhesive gel composition |
| EP3659583B1 (fr) | 2018-11-30 | 2023-06-07 | Viramal Limited | Procédé de préparation d'un agent coagulant, agent coagulant ainsi obtenu et utilisation de cet agent coagulant |
| CN115666621A (zh) | 2020-01-13 | 2023-01-31 | 度勒科特公司 | 具有减少的杂质的持续释放药物递送系统及相关方法 |
| FR3108841B1 (fr) * | 2020-04-06 | 2023-11-03 | Algotherapeutix | Composition pharmaceutique topique sous forme de gel aqueux comprenant au moins de l’amitriptyline |
| CA3203561A1 (fr) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Systemes d'administration de medicament a liberation prolongee et procedes associes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4395420A (en) * | 1981-12-09 | 1983-07-26 | Bernstein Joel E | Method and composition for treating pruritis |
| SI9300468A (en) * | 1992-10-14 | 1994-06-30 | Hoffmann La Roche | Injectable composition for the sustained release of biologically active compounds |
| GB9315856D0 (en) * | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| US5654337A (en) * | 1995-03-24 | 1997-08-05 | II William Scott Snyder | Topical formulation for local delivery of a pharmaceutically active agent |
| US5837289A (en) * | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
| US5885597A (en) * | 1997-10-01 | 1999-03-23 | Medical Research Industries,Inc. | Topical composition for the relief of pain |
-
1999
- 1999-06-29 SK SK2001-2000A patent/SK20012000A3/sk unknown
- 1999-06-29 BR BR9912508-0A patent/BR9912508A/pt not_active Application Discontinuation
- 1999-06-29 HU HU0102728A patent/HUP0102728A3/hu unknown
- 1999-06-29 AU AU48415/99A patent/AU4841599A/en not_active Abandoned
- 1999-06-29 CN CN99810055A patent/CN1331576A/zh active Pending
- 1999-06-29 KR KR1020007014985A patent/KR20010078754A/ko not_active Withdrawn
- 1999-06-29 WO PCT/US1999/014653 patent/WO2000000120A1/fr not_active Ceased
- 1999-06-29 EP EP99932017A patent/EP1093348A4/fr not_active Withdrawn
- 1999-06-29 ID IDW20010231A patent/ID28213A/id unknown
- 1999-06-29 JP JP2000556706A patent/JP2002519310A/ja active Pending
- 1999-06-29 TR TR2000/03801T patent/TR200003801T2/xx unknown
- 1999-06-29 CA CA002335837A patent/CA2335837A1/fr not_active Abandoned
- 1999-06-29 IL IL14042099A patent/IL140420A0/xx unknown
- 1999-06-29 MX MXPA00012767A patent/MXPA00012767A/es unknown
- 1999-06-29 PL PL99345216A patent/PL345216A1/xx unknown
- 1999-06-29 HR HR20000905A patent/HRP20000905A2/hr not_active Application Discontinuation
-
2000
- 2000-12-22 NO NO20006604A patent/NO20006604L/no not_active Application Discontinuation
-
2001
- 2001-01-24 BG BG105175A patent/BG105175A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000000120A9 (fr) | 2000-03-30 |
| EP1093348A4 (fr) | 2003-07-16 |
| CA2335837A1 (fr) | 2000-01-06 |
| CN1331576A (zh) | 2002-01-16 |
| HUP0102728A3 (en) | 2002-12-28 |
| AU4841599A (en) | 2000-01-17 |
| TR200003801T2 (tr) | 2001-06-21 |
| PL345216A1 (en) | 2001-12-03 |
| SK20012000A3 (sk) | 2001-08-06 |
| BR9912508A (pt) | 2001-05-02 |
| ID28213A (id) | 2001-05-10 |
| IL140420A0 (en) | 2002-02-10 |
| JP2002519310A (ja) | 2002-07-02 |
| WO2000000120A1 (fr) | 2000-01-06 |
| NO20006604L (no) | 2001-02-28 |
| HUP0102728A2 (hu) | 2002-03-28 |
| HRP20000905A2 (en) | 2001-08-31 |
| MXPA00012767A (es) | 2002-08-09 |
| NO20006604D0 (no) | 2000-12-22 |
| EP1093348A1 (fr) | 2001-04-25 |
| KR20010078754A (ko) | 2001-08-21 |
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