BG105688A - Utilization of compounds for the prophylaxis and therapy of cerbral ischaemia - Google Patents

Utilization of compounds for the prophylaxis and therapy of cerbral ischaemia

Info

Publication number
BG105688A
BG105688A BG105688A BG10568801A BG105688A BG 105688 A BG105688 A BG 105688A BG 105688 A BG105688 A BG 105688A BG 10568801 A BG10568801 A BG 10568801A BG 105688 A BG105688 A BG 105688A
Authority
BG
Bulgaria
Prior art keywords
prophylaxis
therapy
utilization
compounds
ischaemia
Prior art date
Application number
BG105688A
Other languages
Bulgarian (bg)
Inventor
Gerd Steiner
Kurt SCHNELLHAAS
Wilfried Lubisch
Uta Holzenkamp
Dorothea Starck
Laszlo Szabo
Franz Emling
Francisco Garcia-Ladona
Hans-Peter Hofmann
Liliane Unger
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of BG105688A publication Critical patent/BG105688A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to the utilization of compounds of formula wherein the substituents have the meanings given in the description. The invention also relates to the salts thereof comprising pharmacologically compatible acids for producing medicaments for the prophylaxis and therapy of cerebral ischaemia and strokes. 1 claim
BG105688A 1999-01-11 2001-07-10 Utilization of compounds for the prophylaxis and therapy of cerbral ischaemia BG105688A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900544A DE19900544A1 (en) 1999-01-11 1999-01-11 Use of compounds of formula I for the prophylaxis and therapy of cerebral ischemia
PCT/EP1999/010275 WO2000041697A1 (en) 1999-01-11 1999-12-22 Utilisation of 2-substituted 1,2-benzisothiazole derivatives and 3-substituted tetrahydropyridopyrimidinone derivatives for the prophylaxis and therapy of cerebral ischaemia

Publications (1)

Publication Number Publication Date
BG105688A true BG105688A (en) 2002-02-28

Family

ID=7893835

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105688A BG105688A (en) 1999-01-11 2001-07-10 Utilization of compounds for the prophylaxis and therapy of cerbral ischaemia

Country Status (19)

Country Link
EP (1) EP1140099A1 (en)
JP (1) JP2002534467A (en)
KR (1) KR20010101440A (en)
CN (1) CN1333685A (en)
AR (1) AR029741A1 (en)
AU (1) AU2285100A (en)
BG (1) BG105688A (en)
BR (1) BR9916888A (en)
CA (1) CA2359390A1 (en)
DE (1) DE19900544A1 (en)
HU (1) HUP0200520A3 (en)
IL (1) IL144145A0 (en)
MX (1) MXPA01006966A (en)
NO (1) NO20013408L (en)
PL (1) PL348916A1 (en)
SK (1) SK9682001A3 (en)
TR (1) TR200102009T2 (en)
WO (1) WO2000041697A1 (en)
ZA (1) ZA200105473B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1560488B1 (en) 2002-11-05 2010-09-01 Glaxo Group Limited Antibacterial agents
WO2005030130A2 (en) * 2003-09-23 2005-04-07 Merck & Co., Inc. Isoquinoline potassium channel inhibitors
US8097610B2 (en) * 2005-08-26 2012-01-17 Shionogi & Co., Ltd. Derivative having PPAR agonistic activity
EP2195303A4 (en) * 2007-09-20 2011-07-20 Cortex Pharma Inc 3-substituted 1,2,3-triazin-4-one's and 3-substituted 1,3-pyrimidinone's for enhancing glutamatergic synaptic responses
MA41168A (en) 2014-12-17 2017-10-24 Acraf NEW ANTIBACTERIAL COMPOUNDS
CN108484594B (en) * 2018-02-09 2020-08-04 福建医科大学 Alkoxy substituted tetrahydropyridopyrimidine compound or available salt thereof, and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620643A1 (en) * 1985-06-22 1987-01-22 Sandoz Ag Thiazoles, their preparation and use
DE3831888A1 (en) * 1988-09-20 1990-03-29 Troponwerke Gmbh & Co Kg MEDICINES FOR TREATING APOPLEXIA CEREBRI
JP3036789B2 (en) * 1990-06-22 2000-04-24 三井化学株式会社 Novel heterocyclic compounds and pharmaceutical compositions
DE19746612A1 (en) * 1997-10-22 1999-04-29 Basf Ag New 2-substituted 1,2-benzisothiazole derivatives
DE19747063A1 (en) * 1997-10-24 1999-04-29 Basf Ag New 3-substituted tetrahydropyridopyrimidinone derivatives

Also Published As

Publication number Publication date
BR9916888A (en) 2001-11-20
JP2002534467A (en) 2002-10-15
CA2359390A1 (en) 2000-07-20
CN1333685A (en) 2002-01-30
KR20010101440A (en) 2001-11-14
DE19900544A1 (en) 2000-07-13
HUP0200520A2 (en) 2002-07-29
MXPA01006966A (en) 2002-04-10
AU2285100A (en) 2000-08-01
WO2000041697A1 (en) 2000-07-20
EP1140099A1 (en) 2001-10-10
NO20013408L (en) 2001-08-21
AR029741A1 (en) 2003-07-16
HUP0200520A3 (en) 2003-04-28
ZA200105473B (en) 2002-10-03
SK9682001A3 (en) 2002-03-05
TR200102009T2 (en) 2002-01-21
NO20013408D0 (en) 2001-07-10
PL348916A1 (en) 2002-06-17
IL144145A0 (en) 2002-05-23

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