BG106141A - Заместени бензолактамови съединения - Google Patents

Заместени бензолактамови съединения Download PDF

Info

Publication number: BG106141A
Authority: BG; Bulgaria
Prior art keywords: compound; disorders; disorder; syndrome; methyl
Prior art date: 1999-05-06

Application number

BG106141A

Other languages

Bulgarian (bg)

English (en)

Inventor

Susan SOBOLOV

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-06

Filing date

2001-11-23

Publication date

2002-07-31

2001-11-23 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2002-07-31 Publication of BG106141A publication Critical patent/BG106141A/bg

Links

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150000003839 salts Chemical class 0.000 claims abstract description 47
239000001257 hydrogen Substances 0.000 claims abstract description 38
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 20
229910052799 carbon Inorganic materials 0.000 claims abstract description 19
125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 18
125000001153 fluoro group Chemical group F* 0.000 claims abstract description 16
150000002431 hydrogen Chemical group 0.000 claims abstract description 16
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 16
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Classifications

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- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

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Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
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Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
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Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Physical Education & Sports Medicine (AREA)
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Pulmonology (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
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BG106141A 1999-05-06 2001-11-23 Заместени бензолактамови съединения BG106141A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13285899P	1999-05-06	1999-05-06
PCT/IB2000/000461 WO2000068224A1 (en)	1999-05-06	2000-04-13	Substituted benzolactam compounds

Publications (1)

Publication Number	Publication Date
BG106141A true BG106141A (bg)	2002-07-31

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Application Number	Title	Priority Date	Filing Date
BG106141A BG106141A (bg)	1999-05-06	2001-11-23	Заместени бензолактамови съединения

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EP (1)	EP1175417B1 (is)
JP (1)	JP2002544128A (is)
KR (1)	KR20020015319A (is)
CN (1)	CN1349527A (is)
AP (1)	AP2001002314A0 (is)
AR (1)	AR036320A1 (is)
AT (1)	ATE257478T1 (is)
AU (1)	AU3572800A (is)
BG (1)	BG106141A (is)
BR (1)	BR0010673A (is)
CA (1)	CA2373079A1 (is)
CR (1)	CR6505A (is)
CZ (1)	CZ20013977A3 (is)
DE (1)	DE60007625T2 (is)
DK (1)	DK1175417T3 (is)
DZ (1)	DZ3040A1 (is)
EA (1)	EA200101050A1 (is)
EE (1)	EE200100586A (is)
ES (1)	ES2211520T3 (is)
GE (1)	GEP20043224B (is)
GT (1)	GT200000063A (is)
HK (1)	HK1046144A1 (is)
HR (1)	HRP20010821A2 (is)
HU (1)	HUP0201135A3 (is)
IL (1)	IL145945A0 (is)
IS (1)	IS6122A (is)
MA (1)	MA26731A1 (is)
MY (1)	MY133207A (is)
NO (1)	NO20015395L (is)
NZ (1)	NZ514697A (is)
OA (1)	OA11864A (is)
PA (1)	PA8494901A1 (is)
PE (1)	PE20010119A1 (is)
PL (1)	PL351919A1 (is)
PT (1)	PT1175417E (is)
TN (1)	TNSN00095A1 (is)
TR (1)	TR200103222T2 (is)
UY (1)	UY26135A1 (is)
WO (1)	WO2000068224A1 (is)
ZA (1)	ZA200109116B (is)

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GB0108982D0 (en)	2001-04-10	2001-05-30	Merck Sharp & Dohme	Therapeutic agents
EP1460061A4 (en) *	2001-12-27	2006-05-31	Toray Finechemicals Co Ltd	PROCESS FOR PRODUCING 1-ALCOXYCARBONYL SATURATED NITROGENIC HETEROCYCLIC DERIVATIVE
EP1613348B1 (en)	2003-03-12	2010-06-23	The Arizona Board of Regents on Behalf of the University of Arizona	Methods for modulating angiogenesis with apelin compositions
US7790745B2 (en)	2005-10-21	2010-09-07	Bristol-Myers Squibb Company	Tetrahydroisoquinoline LXR Modulators
WO2009109001A1 (en) *	2008-03-04	2009-09-11	Adelaide Research & Innovation Pty Ltd	Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function
JP6156074B2 (ja) *	2013-11-08	2017-07-05	住友化学株式会社	スクシンイミド化合物及びその用途

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ATE194340T1 (de) *	1992-12-10	2000-07-15	Pfizer	Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
US6180647B1 (en) *	1995-07-07	2001-01-30	Pfizer Inc.	Substituted benzolactam compounds as substance P antagonists
TW340842B (en) *	1995-08-24	1998-09-21	Pfizer	Substituted benzylaminopiperidine compounds
EP0780375B1 (en) *	1995-12-21	2002-09-11	Pfizer Inc.	3-((5-substituted benzyl)amino)-2-phenylpiperidines as substance p antagonists
TW426667B (en) *	1997-11-19	2001-03-21	Pfizer	Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

2000
- 2000-04-13 CN CN00807267A patent/CN1349527A/zh active Pending
- 2000-04-13 NZ NZ514697A patent/NZ514697A/en unknown
- 2000-04-13 CA CA002373079A patent/CA2373079A1/en not_active Abandoned
- 2000-04-13 AT AT00914335T patent/ATE257478T1/de not_active IP Right Cessation
- 2000-04-13 DE DE2000607625 patent/DE60007625T2/de not_active Expired - Fee Related
- 2000-04-13 IL IL14594500A patent/IL145945A0/xx unknown
- 2000-04-13 AP APAP/P/2001/002314A patent/AP2001002314A0/en unknown
- 2000-04-13 HR HR20010821A patent/HRP20010821A2/hr not_active Application Discontinuation
- 2000-04-13 PT PT00914335T patent/PT1175417E/pt unknown
- 2000-04-13 HK HK02107807.6A patent/HK1046144A1/zh unknown
- 2000-04-13 JP JP2000616198A patent/JP2002544128A/ja active Pending
- 2000-04-13 GE GEAP20006190A patent/GEP20043224B/en unknown
- 2000-04-13 TR TR2001/03222T patent/TR200103222T2/xx unknown
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- 2000-04-13 OA OA1200100264A patent/OA11864A/en unknown
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- 2000-04-13 HU HU0201135A patent/HUP0201135A3/hu unknown
- 2000-05-03 TN TNTNSN00095A patent/TNSN00095A1/fr unknown
- 2000-05-03 PA PA20008494901A patent/PA8494901A1/es unknown
- 2000-05-03 DZ DZ000082A patent/DZ3040A1/xx active
- 2000-05-03 UY UY26135A patent/UY26135A1/es not_active Application Discontinuation
- 2000-05-03 MA MA25966A patent/MA26731A1/fr unknown
- 2000-05-04 MY MYPI20001922A patent/MY133207A/en unknown
- 2000-05-04 AR ARP000102150A patent/AR036320A1/es unknown
- 2000-05-05 PE PE2000000418A patent/PE20010119A1/es not_active Application Discontinuation
- 2000-05-05 GT GT200000063A patent/GT200000063A/es unknown
2001
- 2001-10-23 IS IS6122A patent/IS6122A/is unknown
- 2001-11-05 ZA ZA200109116A patent/ZA200109116B/en unknown
- 2001-11-05 NO NO20015395A patent/NO20015395L/no not_active Application Discontinuation
- 2001-11-19 CR CR6505A patent/CR6505A/es not_active Application Discontinuation
- 2001-11-23 BG BG106141A patent/BG106141A/bg unknown

Also Published As

Publication number	Publication date
MA26731A1 (fr)	2004-12-20
TR200103222T2 (tr)	2002-03-21
IL145945A0 (en)	2002-07-25
NO20015395D0 (no)	2001-11-05
EE200100586A (et)	2003-02-17
WO2000068224A1 (en)	2000-11-16
AU3572800A (en)	2000-11-21
DK1175417T3 (da)	2004-04-05
PL351919A1 (en)	2003-06-30
HUP0201135A3 (en)	2003-05-28
HK1046144A1 (zh)	2002-12-27
NZ514697A (en)	2004-04-30
UY26135A1 (es)	2000-12-29
JP2002544128A (ja)	2002-12-24
KR20020015319A (ko)	2002-02-27
PA8494901A1 (es)	2003-12-10
AP2001002314A0 (en)	2001-12-31
DE60007625D1 (de)	2004-02-12
CA2373079A1 (en)	2000-11-16
BR0010673A (pt)	2002-02-19
NO20015395L (no)	2001-12-11
CZ20013977A3 (cs)	2003-10-15
GEP20043224B (en)	2004-04-26
IS6122A (is)	2001-10-23
TNSN00095A1 (fr)	2005-11-10
DE60007625T2 (de)	2004-11-18
GT200000063A (es)	2001-10-27
CR6505A (es)	2004-03-24
MY133207A (en)	2007-10-31
ZA200109116B (en)	2002-11-05
OA11864A (en)	2006-03-03
PT1175417E (pt)	2004-04-30
ATE257478T1 (de)	2004-01-15
AR036320A1 (es)	2004-09-01
CN1349527A (zh)	2002-05-15
EP1175417A1 (en)	2002-01-30
HUP0201135A2 (en)	2002-09-28
DZ3040A1 (fr)	2004-03-27
ES2211520T3 (es)	2004-07-16
HRP20010821A2 (en)	2002-12-31
PE20010119A1 (es)	2001-02-06
EA200101050A1 (ru)	2002-04-25
EP1175417B1 (en)	2004-01-07

Publication	Publication Date	Title
JP3042894B2 (ja)	2000-05-22	サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
US5652246A (en)	1997-07-29	Piperidine compounds
US7626032B2 (en)	2009-12-01	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US7691893B2 (en)	2010-04-06	Chemical compounds
BG107135A (bg)	2003-06-30	Съединения, съдържащи бензоамидпиперидин и сроднисъединения
KR910007239B1 (ko)	1991-09-24	치환된 옥타하이드로벤조(f)퀴놀린의 제조방법
TW201100082A (en)	2011-01-01	Bicyclic and tricyclic compounds as KAT II inhibitors
US4228169A (en)	1980-10-14	1,9-Dihydroxyoctahydrobenzo[c]quinolines and 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones as antiemetic agents
TW201028398A (en)	2010-08-01	Quinolone compound and pharmaceutical composition
US20030105124A1 (en)	2003-06-05	Substituted benzolactam compounds
JP2005511743A (ja)	2005-04-28	新世代の三重標的化したキラルな広域スペクトラム抗菌性の７位置換ピペリジノ−キノロンカルボン酸誘導体、その調製方法、組成物、および医薬としての使用
US20170224713A1 (en)	2017-08-10	Heterocyclic compounds for treating or preventing disorers caused by reduced neurotransmission of serotonin, norephnephrine or dopamine
TW505645B (en)	2002-10-11	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions
IL101589A (en)	1996-10-31	1-(pyrido [3,4-b]-1,4-oxazin-4-yl)- 1H-indoles a process for their preparation and their use as medicaments
BG106141A (bg)	2002-07-31	Заместени бензолактамови съединения
EP2061461B1 (en)	2009-12-23	3-azabicyclo[4.1.0]heptane derivatives for the treatment of depression
US20100029740A1 (en)	2010-02-04	Azabicyclic compounds as serotonin, dopamine and norepinephrine re-uptake inhibitors
US6288225B1 (en)	2001-09-11	Substituted benzolactam compounds as substance P antagonists
WO2009027293A1 (en)	2009-03-05	Compounds
MXPA01011367A (en)	2002-06-05	Substituted benzolactam compounds
US20020052503A1 (en)	2002-05-02	Substituted benzolactam compounds as substance p antagonists
WO2009027295A1 (en)	2009-03-05	3-azabicyclo (4.1.0) heptane derivatives useful as norepinephrine, serotonin or dopamine reuptake inhibitors
WO1996001260A1 (en)	1996-01-18	Pyridonecarboxylic acid derivative, ester thereof, salt thereof, and intermediate for synthesis of these compounds