BG106221A - Назални фармацевтични препарати съдържащи морфин и методи на приложението им - Google Patents

Назални фармацевтични препарати съдържащи морфин и методи на приложението им

Info

Publication number
BG106221A
BG106221A BG106221A BG10622101A BG106221A BG 106221 A BG106221 A BG 106221A BG 106221 A BG106221 A BG 106221A BG 10622101 A BG10622101 A BG 10622101A BG 106221 A BG106221 A BG 106221A
Authority
BG
Bulgaria
Prior art keywords
morphin
methods
application
pharmaceutical preparations
preparations containing
Prior art date
Application number
BG106221A
Other languages
English (en)
Inventor
Raja ACHARI
Charanjit Behl
Jorge DEMEIRELES
Ramneik Dua
Vincent Romeo
Anthony SILENO
Original Assignee
Nastech Pharmaceutical Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nastech Pharmaceutical Co., Inc. filed Critical Nastech Pharmaceutical Co., Inc.
Publication of BG106221A publication Critical patent/BG106221A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретението се отнася до фармацевтичен препаратза назално приложение, съдържащ морфин или неговафармацевтично приемлива сол, при рН стойност приблизително от 3,0 до 7,0. Такива препарати осигуряват повишена абсорбция на морфина или на неговата фармацевтично приемлива сол. При един вариант се осигурява метод за предизвикване на аналгетичен или анестетичен отговор у бозайник. Методът включва назално приложение на терапевтично ефективно количество морфин или негова фармацевтично приемлива сол при рН приблизително от 3,0 до 7,0.
BG106221A 1999-06-16 2001-12-14 Назални фармацевтични препарати съдържащи морфин и методи на приложението им BG106221A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33453799A 1999-06-16 1999-06-16
PCT/US2000/014157 WO2000076506A1 (en) 1999-06-16 2000-05-23 Pharmaceutical formulations and methods comprising intranasal morphine

Publications (1)

Publication Number Publication Date
BG106221A true BG106221A (bg) 2002-08-30

Family

ID=23307687

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106221A BG106221A (bg) 1999-06-16 2001-12-14 Назални фармацевтични препарати съдържащи морфин и методи на приложението им

Country Status (30)

Country Link
US (1) US6677346B1 (bg)
EP (2) EP1183027A4 (bg)
JP (1) JP2003501467A (bg)
KR (1) KR20020016831A (bg)
AU (1) AU774175B2 (bg)
BG (1) BG106221A (bg)
BR (1) BR0012082A (bg)
CA (1) CA2374877C (bg)
CZ (1) CZ20014399A3 (bg)
DE (1) DE10084709T1 (bg)
DK (1) DK200101859A (bg)
EE (1) EE200100677A (bg)
ES (1) ES2197792B1 (bg)
FI (1) FI20012462L (bg)
GB (1) GB2367005A (bg)
HR (1) HRP20010926A2 (bg)
HU (1) HUP0201856A3 (bg)
IS (1) IS6202A (bg)
LT (1) LT4976B (bg)
LU (1) LU90859B1 (bg)
LV (1) LV12859B (bg)
MX (1) MXPA01012879A (bg)
NO (1) NO20015931L (bg)
NZ (1) NZ515783A (bg)
PL (1) PL352556A1 (bg)
SE (1) SE0104203D0 (bg)
SI (1) SI20850A (bg)
SK (1) SK18172001A3 (bg)
TR (1) TR200103613T2 (bg)
WO (1) WO2000076506A1 (bg)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924797D0 (en) 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
CA2423354C (en) * 2000-09-20 2009-12-15 Lee Shahinian Jr. Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications
EP1418862A4 (en) * 2001-06-29 2010-06-09 Leon J Lewandowski INDIVIDUALIZED SEARCH THERAPY
GB0210264D0 (en) * 2002-05-03 2002-06-12 Arakis Ltd The treatment of pain and migraine headache
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
DK2486942T3 (en) 2004-11-24 2019-01-28 Meda Pharmaceuticals Inc COMPOSITIONS CONTAINING AZELASTINE AND PROCEDURES FOR USING IT
US9415034B2 (en) * 2005-01-05 2016-08-16 National Defense Medical Center Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B)
ES2277743B2 (es) * 2005-06-02 2008-12-16 Universidade De Santiago De Compostela Nanoparticulas que comprenden quitosano y ciclodextrina.
WO2007025286A2 (en) * 2005-08-26 2007-03-01 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
US20070212307A1 (en) * 2006-02-10 2007-09-13 Daniel Wermeling Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
WO2008077712A1 (en) * 2006-12-22 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of ophthalmic drugs
GB2477545B (en) * 2010-02-05 2011-12-21 Special Products Ltd A liquid morphine composition for buccal administration
DK2706982T4 (da) 2011-05-13 2021-05-10 Euro Celtique Sa Intranasale farmaceutiske dosisformer omfattende naloxon
AU2012386221A1 (en) 2012-07-26 2015-02-26 Wockhardt Limited Pharmaceutical composition comprising diamorphine for intranasal administration
EP3082817A4 (en) * 2013-12-18 2017-06-21 Aegis Therapeutics, LLC Compositions for drug administration
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
US11389473B2 (en) 2015-01-07 2022-07-19 Tonix Pharmaceuticals Holding Corp. Magnesium-containing oxytocin formulations and methods of use
MX2018012351A (es) 2016-04-12 2019-02-07 Trigemina Inc Formulaciones de oxitocina que contienen magnesio y metodos de uso.
AU2017345767A1 (en) * 2016-10-21 2019-05-16 Somniferum Labs LLC Apparatus for controlled delivery of opioid and other medications
MA50394A (fr) * 2017-10-20 2021-04-28 Chiesi Farm Spa Formulations pharmaceutiques comprenant un agoniste de récepteur d'opioïde en tant que substances actives, leurs procédés de fabrication et leurs utilisations thérapeutiques
EA202091615A1 (ru) 2018-12-21 2021-03-05 Аегис Терапьютикс, Ллс Интраназальные составы на основе эпинефрина и способы лечения заболевания
CN115804754A (zh) * 2022-12-16 2023-03-17 广州新济药业科技有限公司 吗啡鼻喷剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464378A (en) 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
US4464376A (en) 1982-07-22 1984-08-07 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
US5202128A (en) 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
GB9202464D0 (en) * 1992-02-05 1992-03-18 Danbiosyst Uk Composition for nasal administration
DE69434304T2 (de) * 1993-03-26 2005-12-29 Merkus, Franciscus Wilhelmus H.M. Pharmazeutische Zusammensetzungen zur intranasalen Verabreichung von Dihydroergotamin
GB9426102D0 (en) 1994-12-23 1995-02-22 Merck Sharp & Dohme Pharmacuetical compositions
US5874450A (en) * 1996-09-27 1999-02-23 Nastech Pharmaceutical Company, Inc. Intranasal formulations for promoting sleep and method of using the same

Also Published As

Publication number Publication date
EP1419774A1 (en) 2004-05-19
LT2001119A (en) 2002-07-25
SE0104203L (sv) 2001-12-14
FI20012462A7 (fi) 2002-01-16
HUP0201856A3 (en) 2004-12-28
GB2367005A (en) 2002-03-27
TR200103613T2 (tr) 2004-08-23
CA2374877C (en) 2004-04-13
HUP0201856A1 (en) 2002-09-28
PL352556A1 (en) 2003-08-25
SE0104203D0 (sv) 2001-12-14
NO20015931L (no) 2002-02-08
DE10084709T1 (de) 2002-09-26
KR20020016831A (ko) 2002-03-06
EP1183027A1 (en) 2002-03-06
SI20850A (sl) 2002-10-31
LU90859B1 (en) 2002-01-24
CZ20014399A3 (cs) 2002-06-12
DK200101859A (da) 2001-12-12
NZ515783A (en) 2004-05-28
BR0012082A (pt) 2002-05-07
JP2003501467A (ja) 2003-01-14
CA2374877A1 (en) 2000-12-21
ES2197792A1 (es) 2004-01-01
ES2197792B1 (es) 2005-05-01
WO2000076506A1 (en) 2000-12-21
AU774175B2 (en) 2004-06-17
IS6202A (is) 2001-12-14
AU5156100A (en) 2001-01-02
NO20015931D0 (no) 2001-12-04
FI20012462L (fi) 2002-01-16
SK18172001A3 (sk) 2002-07-02
LT4976B (lt) 2002-12-30
EP1183027A4 (en) 2003-02-05
EE200100677A (et) 2003-02-17
HRP20010926A2 (en) 2003-04-30
US6677346B1 (en) 2004-01-13
LV12859B (en) 2002-12-20
GB0128383D0 (en) 2002-01-16
MXPA01012879A (es) 2003-06-24

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